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5-Fluorouracil (5-FU) inibitore della timidilato sintasi
N. Cat.S1209
Struttura chimica
Peso molecolare: 130.08
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Purezza:
99.97%
99.97
| Target correlati | HDAC PARP ATM/ATR DNA-PK WRN Topoisomerase PPAR Sirtuin Casein Kinase eIF |
|---|---|
| Altro DNA/RNA Synthesis Inibitori | CX-5461 (Pidnarulex) B02 SCR7 Favipiravir (T-705) EED226 RK-33 BMH-21 Triapine (3-AP) Carmofur YK-4-279 |
Coltura cellulare, trattamento e concentrazione di lavoro
| Linee cellulari | Tipo di saggio | Concentrazione | Tempo di incubazione | Formulazione | Descrizione dellattività | PMID |
|---|---|---|---|---|---|---|
| NCI-H292 | Growth Inhibition Assay | 72 h | IC50> 25 μg/mL | 24095176 | ||
| HL-60 | Growth Inhibition Assay | 72 h | IC50=8.601 μg/mL | 24095176 | ||
| HT-29 | Growth Inhibition Assay | 72 h | IC50> 25 μg/mL | 24095176 | ||
| MCF-7 | Growth Inhibition Assay | 72 h | IC50=20 μg/mL | 24095176 | ||
| L1210/0 | Function assay | Effect on L1210/0 cells in culture, IC50 = 0.3 μM. | 2362278 | |||
| CCRF-CEM | Function assay | Effect on CCRF-CEM cells in culture, IC50 = 2 μM. | 2362278 | |||
| P388 | Antiproliferative assay | 48 hrs | Antiproliferative activity against mouse P388 cells after 48 hrs by MTT assay, IC50 = 0.609 μM. | 2778449 | ||
| HT-29 | Antiproliferative assay | 96 hrs | Antiproliferative activity against human HT-29 cells after 96 hrs by MTT assay, IC50 = 0.69 μM. | 2778449 | ||
| L1210 | Growth inhibition assay | Inhibition of cell growth of L1210 mouse Leukemia cells, IC50 = 0.3 μM. | 2967375 | |||
| L1210 | Growth inhibition assay | Concentration required for the 50% inhibition of growth of L1210 mouse leukemia cells in culture, IC50 = 0.5 μM. | 7120290 | |||
| CCRF-CEM | Growth inhibition assay | Concentration required for the 50% inhibition of growth of CCRF-CEM human leukemia cells in culture, IC50 = 5 μM. | 7120290 | |||
| L1210 | Growth inhibition assay | 48 hrs | In vitro growth inhibition of L1210 cells 48 hours after administration of compound, IC50 = 0.12 μM. | 7629806 | ||
| L1210 | Growth inhibition assay | 24 hrs | In vitro growth inhibition of L1210 cells 24 hours after administration of compound, IC50 = 0.22 μM. | 7629806 | ||
| L1210 | Growth inhibition assay | 8 hrs | In vitro growth inhibition of L1210 cells 8 hours after administration of compound, IC50 = 0.63 μM. | 7629806 | ||
| L1210 | Growth inhibition assay | 2 hrs | In vitro growth inhibition of L1210 cells 2 hours after administration of compound, IC50 = 2.2 μM. | 7629806 | ||
| CHO | Growth inhibition assay | Growth inhibitory activity against CHO cells in culture., IC50 = 5 μM. | 7853342 | |||
| SCLC | Cytotoxicity assay | Cytotoxicity against human SCLC cells resistant to cisplatin (SCLC/CDDP), IC50 = 8.4 μM. | 8258835 | |||
| T-24 | Cytotoxicity assay | Tested for cytotoxicity against antigen negative T-24 bladder carcinoma cells having only 3-5% antigen expression, IC50 = 4.1 μM. | 8496926 | |||
| 791T | Cytotoxicity assay | Tested for cytotoxicity against antigen positive 791T osteosarcoma cells having only 3-5% antigen expression, IC50 = 5.5 μM. | 8496926 | |||
| 9L | Anticancer assay | Tested in vitro for anticancer activity against 9L cells, IC50 = 1 μM. | 10072683 | |||
| SK-MEL-28 | Anticancer assay | Tested in vitro for anticancer activity against SK-MEL-28 cells, IC50 = 4.5 μM. | 10072683 | |||
| PBM | Cytotoxicity assay | Tested in vitro for cytotoxicity against PBM cells, IC50 = 5 μM. | 10072683 | |||
| Vero | Cytotoxicity assay | Tested in vitro for cytotoxicity against Vero cells, IC50 = 6.81 μM. | 10072683 | |||
| SK-MES-1 | Anticancer assay | Tested in vitro for anticancer activity against SK-MES-1 cells, IC50 = 13.1 μM. | 10072683 | |||
| HepG2 | Anticancer assay | Tested in vitro for anticancer activity against HepG2 cells, IC50 = 37.9 μM. | 10072683 | |||
| MCF-7 | Anticancer assay | Tested in vitro for anticancer activity against MCF-7 cells, IC50 = 41 μM. | 10072683 | |||
| L1210 | Cytotoxicity assay | In vitro cytotoxicity against murine Leukemia L1210 cells., IC50 = 0.62 μM. | 10229634 | |||
| KB | Cytotoxicity assay | In vitro cytotoxicity against human oral epidermoid carcinoma KB cells., IC50 = 2.3 μM. | 10229634 | |||
| L1210 | Growth inhibition assay | Concentration required to inhibit 50% of cell growth on murine L1210 cells., IC50 = 0.28 μM. | 11052798 | |||
| P388 D1 | Growth inhibition assay | Concentration required to inhibit 50% of cell growth on murine P388 D1 cells., IC50 = 0.49 μM. | 11052798 | |||
| Molt 4/C8 | Growth inhibition assay | Concentration required to inhibit 50% of cell growth on human Molt 4/C8 cells., IC50 = 23 μM. | 11052798 | |||
| L1210 | Growth inhibition assay | 48 hrs | Growth inhibition in L1210 mouse Leukemia cells for a treatment time of 48 hr, IC50 = 0.125 μM. | 11063625 | ||
| L1210 | Growth inhibition assay | 24 hrs | Growth inhibition in L1210 mouse Leukemia cells for a treatment time of 24 hr, IC50 = 0.22 μM. | 11063625 | ||
| L1210 | Growth inhibition assay | 8 hrs | Growth inhibition in L1210 mouse Leukemia cells for a treatment time of 8 hr, IC50 = 0.63 μM. | 11063625 | ||
| L1210 | Growth inhibition assay | 2 hrs | Growth inhibition in L1210 mouse Leukemia cells for a treatment time of 2 hr, IC50 = 2.2 μM. | 11063625 | ||
| Colon 26-L5 | Antiproliferative assay | 72 hrs | Antiproliferative activity against mouse Colon 26-L5 cells assessed as cell viability after 72 hrs by MTT assay, IC50 = 0.5 μM. | 11575942 | ||
| B16-BL6 | Antiproliferative assay | 72 hrs | Antiproliferative activity against mouse B16-BL6 cells assessed as cell viability after 72 hrs by MTT assay, IC50 = 0.6 μM. | 11575942 | ||
| HT1080 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human HT1080 cells assessed as cell viability after 72 hrs by MTT assay, IC50 = 1.5 μM. | 11575942 | ||
| L1210 | Growth inhibition assay | 48 hrs | Growth inhibition in L1210 mouse leukemia cells after 48 hr treatment, IC50 = 0.2 μM. | 11728193 | ||
| L1210 | Growth inhibition assay | 24 hrs | Growth inhibition in L1210 mouse leukemia cells after 24 h treatment, IC50 = 0.36 μM. | 11728193 | ||
| L1210 | Growth inhibition assay | 8 hrs | Growth inhibition in L1210 mouse leukemia cells after 8 h treatment, IC50 = 1.01 μM. | 11728193 | ||
| L1210 | Growth inhibition assay | 2 hrs | Growth inhibition in L1210 mouse leukemia cells after 2 hr treatment, IC50 = 2.5 μM. | 11728193 | ||
| HL60 | Function assay | In vitro inhibitory concentration against proliferation of HL60 cells, IC50 = 1.5 μM. | 12877593 | |||
| HT1080 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human HT1080 cells after 72 hrs by MTT assay, IC50 = 3.7 μM. | 14640513 | ||
| HCT116 | Cytotoxicity assay | 96 hrs | Cytotoxicity against human HCT116 cells after 96 hrs by MTT assay, IC50 = 4.93 μM. | 15387639 | ||
| DLD1 | Cytotoxicity assay | 96 hrs | Cytotoxicity against human DLD1 cells after 96 hrs by MTT assay, IC50 = 7.38 μM. | 15387639 | ||
| HeLaS3 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human HeLaS3 cells after 72 hrs by WST1 assay, IC50 = 5.4 μM. | 15387656 | ||
| HeLaS3 | Cytotoxicity assay | Cytotoxicity against human HeLaS3 cells by WST1 assay, IC50 = 5.4 μM. | 15568771 | |||
| MCF-7 | Antiproliferative assay | Antiproliferative activity in MCF-7 human breast cancer cells, IC50 = 4.8 μM. | 15658875 | |||
| MDA-MB 231 | Antiproliferative assay | Antiproliferative activity in MDA-MB 231 human breast cancer cells, IC50 = 9.6 μM. | 15658875 | |||
| A549 | Cytotoxicity assay | 96 hrs | Cytotoxicity against human A549 cells after 96 hrs by MTT assay, IC50 = 1.4 μM. | 16499317 | ||
| HCT8 | Cytotoxicity assay | 96 hrs | Cytotoxicity against human HCT8 cells after 96 hrs by MTT assay, IC50 = 4.2 μM. | 16499317 | ||
| BEL-7402 | Cytotoxicity assay | 96 hrs | Cytotoxicity against human BEL-7402 cells after 96 hrs by MTT assay, IC50 = 4.2 μM. | 16499317 | ||
| A2780 | Cytotoxicity assay | 96 hrs | Cytotoxicity against human A2780 cells after 96 hrs by MTT assay, IC50 = 5 μM. | 16499317 | ||
| BGC823 | Cytotoxicity assay | 96 hrs | Cytotoxicity against human BGC823 cells after 96 hrs by MTT assay, IC50 = 5.4 μM. | 16499317 | ||
| HCT116 | Cytotoxicity assay | Cytotoxicity against human HCT116 cells, IC50 = 2.04 μM. | 16996657 | |||
| COLO205 | Cytotoxicity assay | Cytotoxicity against human COLO205 cells, IC50 = 3.39 μM. | 16996657 | |||
| RPMI8226 | Cytotoxicity assay | Cytotoxicity against human RPMI8226 cells, IC50 = 3.55 μM. | 16996657 | |||
| HCC2998 | Cytotoxicity assay | Cytotoxicity against human HCC2998 cells, IC50 = 5.75 μM. | 16996657 | |||
| HCT15 | Cytotoxicity assay | Cytotoxicity against human HCT15 cells, IC50 = 6.61 μM. | 16996657 | |||
| KM12 | Cytotoxicity assay | Cytotoxicity against human KM12 cells, IC50 = 7.94 μM. | 16996657 | |||
| SW620 | Cytotoxicity assay | Cytotoxicity against human SW620 cells, IC50 = 18.6 μM. | 16996657 | |||
| KB | Cytotoxicity assay | 48 hrs | Cytotoxicity against human KB cells after 48 hrs, IC50 = 13.4 μM. | 17000031 | ||
| HT29 | Antiproliferative assay | Antiproliferative activity against HT29 cells, IC50 = 7.3 μM. | 17110105 | |||
| Vero | Cytotoxicity assay | Cytotoxicity against Vero cells, IC50 = 0.2 μM. | 17234303 | |||
| SW1116 | Cytotoxicity assay | Cytotoxicity against SW1116 cells by MTT colometric method, IC50 = 37 μM. | 17253861 | |||
| HL60 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human HL60 cells after 48 hrs by MTT assay, IC50 = 0.16 μM. | 17291040 | ||
| Bel7402 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human Bel7402 cells after 48 hrs by MTT assay, IC50 = 23.21 μM. | 17291040 | ||
| BGC823 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human BGC823 cells after 48 hrs by MTT assay, IC50 = 31.16 μM. | 17291040 | ||
| HT29 | Cytotoxicity assay | Cytotoxicity against human HT29 cells by MTT microassay, IC50 = 0.6 μM. | 17320246 | |||
| Hep 3B | Cytotoxicity assay | Cytotoxicity against human Hep 3B cells by MTT microassay, IC50 = 0.6 μM. | 17320246 | |||
| MCF7 | Cytotoxicity assay | Cytotoxicity against human MCF7 cells by MTT microassay, IC50 = 1.5 μM. | 17320246 | |||
| A549 | Cytotoxicity assay | Cytotoxicity against human A549 cells by MTT microassay, IC50 = 3.1 μM. | 17320246 | |||
| MCF7 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human MCF7 cells after 72 hrs, IC50 = 4.8 μM. | 17336074 | ||
| MDA-MB-231 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human MDA-MB-231 cells after 72 hrs, IC50 = 9.6 μM. | 17336074 | ||
| Caco-2 | Growth inhibition assay | 10 days | Growth inhibition of human Caco-2 cells after 10 days, IC50 = 1.5 μM. | 17337193 | ||
| L1210/0 | Cytotoxicity assay | 48 hrs | Cytotoxicity against mouse L1210/0 cells after 48 hrs, IC50 = 0.31 μM. | 17341060 | ||
| HCT116 | Antitumor assay | Antitumor activity against human HCT116 cells, GI50 = 0.39811 μM. | 17446077 | |||
| NCI-H460 | Antitumor assay | Antitumor activity against human NCI-H460 cells, GI50 = 1 μM. | 17446077 | |||
| SF539 | Antitumor assay | Antitumor activity against human SF539 cells, GI50 = 1.25893 μM. | 17446077 | |||
| MCF7 | Antitumor assay | Antitumor activity against human MCF7 cells, GI50 = 1.58489 μM. | 17446077 | |||
| HCC2998 | Antitumor assay | Antitumor activity against human HCC2998 cells, GI50 = 1.58489 μM. | 17446077 | |||
| A549 | Antitumor assay | Antitumor activity against human A549 cells, GI50 = 1.99526 μM. | 17446077 | |||
| CAKI-1 | Antitumor assay | Antitumor activity against human CAKI-1 cells, GI50 = 3.98107 μM. | 17446077 | |||
| SR | Antitumor assay | Antitumor activity against human SR cells, GI50 = 3.98107 μM. | 17446077 | |||
| UO31 | Antitumor assay | Antitumor activity against human UO31 cells, GI50 = 5.01187 μM. | 17446077 | |||
| RPMI8226 | Antitumor assay | Antitumor activity against human RPMI8226 cells, GI50 = 5.01187 μM. | 17446077 | |||
| HCT15 | Antitumor assay | Antitumor activity against human HCT15 cells, GI50 = 6.30957 μM. | 17446077 | |||
| HT29 | Antitumor assay | Antitumor activity against human HT29 cells, GI50 = 6.30957 μM. | 17446077 | |||
| LOX IMVI | Antitumor assay | Antitumor activity against human LOX IMVI cells, GI50 = 6.30957 μM. | 17446077 | |||
| COLO205 | Antitumor assay | Antitumor activity against human COLO205 cells, GI50 = 6.30957 μM. | 17446077 | |||
| KM12 | Antitumor assay | Antitumor activity against human KM12 cells, GI50 = 10 μM. | 17446077 | |||
| ACHN | Antitumor assay | Antitumor activity against human ACHN cells, GI50 = 10 μM. | 17446077 | |||
| DU145 | Antitumor assay | Antitumor activity against human DU145 cells, GI50 = 10 μM. | 17446077 | |||
| A498 | Antitumor assay | Antitumor activity against human A498 cells, GI50 = 10 μM. | 17446077 | |||
| MDA-MB-435 | Antitumor assay | Antitumor activity against human MDA-MB-435 cells, GI50 = 10 μM. | 17446077 | |||
| MOLT4 | Antitumor assay | Antitumor activity against human MOLT4 cells, GI50 = 12.5892 μM. | 17446077 | |||
| NCI-H23 | Antitumor assay | Antitumor activity against human NCI-H23 cells, GI50 = 12.5892 μM. | 17446077 | |||
| IGROV1 | Antitumor assay | Antitumor activity against human IGROV1 cells, GI50 = 12.5892 μM. | 17446077 | |||
| UACC62 | Antitumor assay | Antitumor activity against human UACC62 cells, GI50 = 12.5892 μM. | 17446077 | |||
| SK-MEL-5 | Antitumor assay | Antitumor activity against human SK-MEL-5 cells, GI50 = 12.5892 μM. | 17446077 | |||
| 786-0 | Antitumor assay | Antitumor activity against human 786-0 cells, GI50 = 12.5892 μM. | 17446077 | |||
| K562 | Antitumor assay | Antitumor activity against human K562 cells, GI50 = 19.9526 μM. | 17446077 | |||
| HOP62 | Antitumor assay | Antitumor activity against human HOP62 cells, GI50 = 19.9526 μM. | 17446077 | |||
| MALME-3M | Antitumor assay | Antitumor activity against human MALME-3M cells, GI50 = 19.9526 μM. | 17446077 | |||
| OVCAR8 | Antitumor assay | Antitumor activity against human OVCAR8 cells, GI50 = 19.9526 μM. | 17446077 | |||
| HL60 (TB) | Antitumor assay | Antitumor activity against human HL60 (TB) cells, GI50 = 19.9526 μM. | 17446077 | |||
| NCI-H322 | Antitumor assay | Antitumor activity against human NCI-H322 cells, GI50 = 19.9526 μM. | 17446077 | |||
| SN12C | Antitumor assay | Antitumor activity against human SN12C cells, GI50 = 25.1189 μM. | 17446077 | |||
| OVCAR-3 | Antitumor assay | Antitumor activity against human OVCAR-3 cells, GI50 = 25.1189 μM. | 17446077 | |||
| SW620 | Antitumor assay | Antitumor activity against human SW620 cells, GI50 = 25.1189 μM. | 17446077 | |||
| CCRF-CEM | Antitumor assay | Antitumor activity against human CCRF-CEM cells, GI50 = 31.6228 μM. | 17446077 | |||
| U251 | Antitumor assay | Antitumor activity against human U251 cells, GI50 = 39.8107 μM. | 17446077 | |||
| NCI-H522 | Antitumor assay | Antitumor activity against human NCI-H522 cells, GI50 = 39.8107 μM. | 17446077 | |||
| NCI/ADR-RES | Antitumor assay | Antitumor activity against human NCI/ADR-RES cells, GI50 = 39.8107 μM. | 17446077 | |||
| SW480 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human SW480 cells after 72 hrs by MTT method, IC50 = 8.1 μM. | 17524655 | ||
| MDA-MB-435S | Antiproliferative assay | 72 hrs | Antiproliferative activity against human MDA-MB-435S cells after 72 hrs by MTT method, IC50 = 14.5 μM. | 17524655 | ||
| HCCLM7 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human HCCLM7 cells after 72 hrs by MTT method, IC50 = 18.6 μM. | 17524655 | ||
| Caco-2 | Growth inhibition assay | Growth inhibition of human Caco-2 cells, IC50 = 1.5 μM. | 17548129 | |||
| MCF7 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human MCF7 cells after 72 hrs, IC50 = 0.3 μM. | 17548198 | ||
| HCT116 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human HCT116 cells after 72 hrs, IC50 = 2.8 μM. | 17548198 | ||
| SW480 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human SW480 cells after 72 hrs, IC50 = 3.5 μM. | 17548198 | ||
| SW48 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human SW48 cells after 72 hrs, IC50 = 5.3 μM. | 17548198 | ||
| DLD1 | Growth inhibition assay | Growth inhibition of human DLD1 cells, IC50 = 4.5 μM. | 17553685 | |||
| Caco-2 | Growth inhibition assay | 10 days | Growth inhibition of human Caco-2 cells after 10 days, IC50 = 1.5 μM. | 17555969 | ||
| colon cancer cell | Cytotoxicity assay | Cytotoxicity against human colon cancer cells, GI50 = 5.75 μM. | 17562365 | |||
| A549 | Cytotoxicity assay | 48 hrs | Cytotoxicity against A549 cells after 48 hrs by MTT assay, IC50 = 9.2 μM. | 17604394 | ||
| L1210 | Cytostatic activity assay | Cytostatic activity against mouse L1210 cells, IC50 = 0.28 μM. | 17931862 | |||
| CEM | Cytostatic activity assay | Cytostatic activity against human CEM cells, IC50 = 9 μM. | 17931862 | |||
| Molt4/C8 | Cytostatic activity assay | Cytostatic activity against human Molt4/C8 cells, IC50 = 23 μM. | 17931862 | |||
| Caco-2 | Growth inhibition assay | 10 days | Growth inhibition of human Caco-2 cells after 10 days, IC50 = 1.5 μM. | 18037195 | ||
| MCF7 | Antiproliferative assay | 3 days | Antiproliferative activity against human MCF7 cells after 3 days by SRB assay, IC50 = 4.32 μM. | 18069093 | ||
| MCF7 | Antiproliferative assay | Antiproliferative activity against human MCF7 cells, IC50 = 4.32 μM. | 18194866 | |||
| embryonic cell | Function assay | Induction of cleavage arrest in embryonic cells of stage 8 Xenopus laevis blastulae, IC50 = 26.8 μM. | 18271558 | |||
| HepG2 | Cytotoxicity assay | Cytotoxicity against human HepG2 cells, IC50 = 18.7 μM. | 18302336 | |||
| L1210 | Antiproliferative assay | 2 days | Antiproliferative activity against mouse L1210 cells after 2 days by MTT assay, IC50 = 0.69 μM. | 18424155 | ||
| MCF7 | Antiproliferative assay | 3 days | Antiproliferative activity against human MCF7 cells after 3 days by MTT assay, IC50 = 4.5 μM. | 18424155 | ||
| MiaPaCa2 | Antiproliferative assay | 3 days | Antiproliferative activity against human MiaPaCa2 cells after 3 days by MTT assay, IC50 = 6.5 μM. | 18424155 | ||
| SW620 | Antiproliferative assay | 3 days | Antiproliferative activity against human SW620 cells after 3 days by MTT assay, IC50 = 8.7 μM. | 18424155 | ||
| HepG2 | Antiproliferative assay | 3 days | Antiproliferative activity against human HepG2 cells after 3 days by MTT assay, IC50 = 9.2 μM. | 18424155 | ||
| CEM | Antiproliferative assay | 3 days | Antiproliferative activity against human CEM cells after 3 days by MTT assay, IC50 = 9.23 μM. | 18424155 | ||
| WI38 | Cytotoxicity assay | 3 days | Cytotoxicity against human WI38 cells after 3 days by MTT assay, IC50 = 10 μM. | 18424155 | ||
| HeLa | Antiproliferative assay | 3 days | Antiproliferative activity against human HeLa cells after 3 days by MTT assay, IC50 = 16 μM. | 18424155 | ||
| Molt4/C8 | Antiproliferative assay | 3 days | Antiproliferative activity against human Molt4/C8 cells after 3 days by MTT assay, IC50 = 20 μM. | 18424155 | ||
| colon 26-L5 | Cytotoxicity assay | 72 hrs | Cytotoxicity against mouse colon 26-L5 cells after 72 hrs by MTT assay, IC50 = 0.46 μM. | 18440233 | ||
| HeLa | Cytotoxicity assay | 72 hrs | Cytotoxicity against human HeLa cells after 72 hrs by MTT assay, IC50 = 0.77 μM. | 18440233 | ||
| LLC | Cytotoxicity assay | 72 hrs | Cytotoxicity against mouse LLC cells after 72 hrs by MTT assay, IC50 = 2.59 μM. | 18440233 | ||
| B16-BL6 | Cytotoxicity assay | 72 hrs | Cytotoxicity against mouse B16-BL6 cells after 72 hrs by MTT assay, IC50 = 5.78 μM. | 18440233 | ||
| A549 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human A549 cells after 72 hrs by MTT assay, IC50 = 9.19 μM. | 18440233 | ||
| HT1080 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human HT1080 cells after 72 hrs by MTT assay, IC50 = 9.45 μM. | 18440233 | ||
| HCT116 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human HCT116 cells expressing p53 gene after 72 hrs by proliferative assay, IC50 = 6.36 μM. | 18469809 | ||
| A2780 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human A2780 cells expressing p53 gene after 72 hrs by proliferative assay, IC50 = 7.21 μM. | 18469809 | ||
| COLO205 | Antiproliferative assay | 72 hrs | Antiproliferative activity against p53 deficient human COLO205 cells after 72 hrs, IC50 = 11.63 μM. | 18469809 | ||
| U2OS | Antiproliferative assay | 72 hrs | Antiproliferative activity against human U2OS cells expressing p53 gene after 72 hrs by proliferative assay, IC50 = 13.18 μM. | 18469809 | ||
| PC3 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human PC3 cells expressing p53 gene after 72 hrs by proliferative assay, IC50 = 13.77 μM. | 18469809 | ||
| HCT15 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human HCT15 cells expressing p53 gene after 72 hrs by proliferative assay, IC50 = 18.24 μM. | 18469809 | ||
| SW480 | Antiproliferative assay | 72 hrs | Antiproliferative activity against p53 deficient human SW480 cells after 72 hrs by proliferative assay, IC50 = 26.26 μM. | 18469809 | ||
| MCF7 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human MCF7 cells expressing p53 gene after 72 hrs by proliferative assay, IC50 = 26.67 μM. | 18469809 | ||
| HCT116/E6 | Antiproliferative assay | 72 hrs | Antiproliferative activity against p53 deficient human HCT116/E6 cells after 72 hrs by proliferative assay, IC50 = 28.91 μM. | 18469809 | ||
| A2780/E6 | Antiproliferative assay | 72 hrs | Antiproliferative activity against p53 deficient human A2780/E6 cells after 72 hrs by proliferative assay, IC50 = 38.67 μM. | 18469809 | ||
| HL60 | Antiproliferative assay | 3 days | Antiproliferative activity against human HL60 cells after 3 days by trypan blue staining, GI50 = 3.8 μM. | 18491866 | ||
| HT29 | Cytotoxicity assay | Cytotoxicity against human HT29 cells by MTT assay, IC50 = 0.6 μM. | 18606546 | |||
| Hep3B | Cytotoxicity assay | Cytotoxicity against human Hep3B cells by MTT assay, IC50 = 0.6 μM. | 18606546 | |||
| MCF7 | Cytotoxicity assay | Cytotoxicity against human MCF7 cells by MTT assay, IC50 = 1.5 μM. | 18606546 | |||
| A549 | Cytotoxicity assay | Cytotoxicity against human A549 cells by MTT assay, IC50 = 3.1 μM. | 18606546 | |||
| HaCaT | Growth inhibition assay | 72 hrs | Growth inhibition of human HaCaT cells after 72 hrs by MTT assay, IC50 = 0.4 μM. | 18640746 | ||
| H460 | Growth inhibition assay | 72 hrs | Growth inhibition of human H460 cells after 72 hrs by MTT assay, IC50 = 2 μM. | 18640746 | ||
| HeLa | Growth inhibition assay | 72 hrs | Growth inhibition of human HeLa cells after 72 hrs by MTT assay, IC50 = 4 μM. | 18640746 | ||
| SW620 | Growth inhibition assay | 72 hrs | Growth inhibition of human SW620 cells after 72 hrs by MTT assay, IC50 = 9 μM. | 18640746 | ||
| MIAPaCa2 | Growth inhibition assay | 72 hrs | Growth inhibition of human MIAPaCa2 cells after 72 hrs by MTT assay, IC50 = 10 μM. | 18640746 | ||
| MCF7 | Growth inhibition assay | 72 hrs | Growth inhibition of human MCF7 cells after 72 hrs by MTT assay, IC50 = 15 μM. | 18640746 | ||
| B16 | Cytotoxicity assay | Cytotoxicity against mouse B16 cells by MTT assay, IC50 = 8.73 μM. | 18644718 | |||
| A549 | Cytotoxicity assay | Cytotoxicity against human A549 cells by MTT assay, IC50 = 10.85 μM. | 18644718 | |||
| SW480 | Cytotoxicity assay | Cytotoxicity against human SW480 cells by MTT assay, IC50 = 13.16 μM. | 18644718 | |||
| BEL-7402 | Cytotoxicity assay | Cytotoxicity against human BEL-7402 cells by MTT assay, IC50 = 14.41 μM. | 18644718 | |||
| BGC-7901 | Cytotoxicity assay | Cytotoxicity against human BGC-7901 cells by MTT assay, IC50 = 16.35 μM. | 18644718 | |||
| HL60 | Cytotoxicity assay | Cytotoxicity against human HL60 cells by MTT assay, IC50 = 21.38 μM. | 18644718 | |||
| 3T3 | Cytotoxicity assay | 48 hrs | Cytotoxicity against BALB mouse 3T3 cells after 48 hrs, GI50 = 1.54 μM. | 18798609 | ||
| H460 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human H460 cells after 48 hrs, GI50 = 4.1 μM. | 18798609 | ||
| MCF7 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human MCF7 cells after 48 hrs, GI50 = 6.5 μM. | 18798609 | ||
| HT29 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human HT29 cells after 48 hrs, GI50 = 8.9 μM. | 18798609 | ||
| PC3 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human PC3 cells after 48 hrs, GI50 = 14.6 μM. | 18798609 | ||
| DU145 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human DU145 cells after 48 hrs, GI50 = 15.4 μM. | 18798609 | ||
| K562 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human K562 cells after 48 hrs, GI50 = 16.7 μM. | 18798609 | ||
| M14 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human M14 cells after 48 hrs, GI50 = 22.4 μM. | 18798609 | ||
| colon cancer cell | Growth inhibition assay | 48 hrs | Growth inhibition of human Colon cancer cells after 48 hrs, GI50 = 8.37 μM. | 18950904 | ||
| leukemia cell | Growth inhibition assay | 48 hrs | Growth inhibition of human leukemia cells after 48 hrs, GI50 = 15.09 μM. | 18950904 | ||
| prostate cancer cell | Growth inhibition assay | 48 hrs | Growth inhibition of human prostate cancer cells after 48 hrs, GI50 = 22.7 μM. | 18950904 | ||
| renal cancer cell | Growth inhibition assay | 48 hrs | Growth inhibition of human renal cancer cells after 48 hrs, GI50 = 45.6 μM. | 18950904 | ||
| KB | Cytotoxicity assay | Cytotoxicity against human KB cells by MTT assay, IC50 = 0.00446 μM. | 19345581 | |||
| NCI60 | Growth inhibition assay | Growth inhibition of human NCI60 cells, GI50 = 17.7 μM. | 19398334 | |||
| A549 | Cytotoxicity assay | Cytotoxicity against human A549 cells by SRB method, IC50 = 20.8 μM. | 19422203 | |||
| PC3 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay, IC50 = 0.016 μM. | 19423198 | ||
| A431 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human A431 cells after 48 hrs by MTT assay, IC50 = 0.018 μM. | 19423198 | ||
| MCF7 | Antiproliferative assay | 24 hrs | Antiproliferative activity against human MCF7 cells after 24 hrs by MTT assay, IC50 = 4.3 μM. | 19560842 | ||
| Bel7402 | Antiproliferative assay | 24 hrs | Antiproliferative activity against human Bel7402 cells after 24 hrs by MTT assay, IC50 = 4.7 μM. | 19560842 | ||
| HeLa | Cytotoxicity assay | 48 hrs | Cytotoxicity against human HeLa cells after 48 hrs by MTT assay, GI50 = 10 μM. | 19572613 | ||
| MCF7 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay, GI50 = 15 μM. | 19572613 | ||
| HeLa | Cytotoxicity assay | 48 hrs | Cytotoxicity against human HeLa cells after 48 hrs by MTT assay, IC50 = 10 μM. | 19618920 | ||
| MCF7 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay, IC50 = 15 μM. | 19618920 | ||
| SW1573 | Growth inhibition assay | 48 hrs | Growth inhibition of human SW1573 cells after 48 hrs by sulforhodamine B assay, GI50 = 4.1 μM. | 19664930 | ||
| A2780 | Growth inhibition assay | 48 hrs | Growth inhibition of human A2780 cells after 48 hrs by sulforhodamine B assay, GI50 = 4.4 μM. | 19664930 | ||
| HBL100 | Growth inhibition assay | 48 hrs | Growth inhibition of human HBL100 cells after 48 hrs by sulforhodamine B assay, GI50 = 5.5 μM. | 19664930 | ||
| HeLa | Growth inhibition assay | 48 hrs | Growth inhibition of human HeLa cells after 48 hrs by sulforhodamine B assay, GI50 = 19 μM. | 19664930 | ||
| T47D | Growth inhibition assay | 48 hrs | Growth inhibition of human T47D cells after 48 hrs by sulforhodamine B assay, GI50 = 29 μM. | 19664930 | ||
| Colon 26-L5 | Cytotoxicity assay | 72 hrs | Cytotoxicity against mouse Colon 26-L5 cells after 72 hrs by MTT assay, IC50 = 0.41 μM. | 19689125 | ||
| HeLa | Cytotoxicity assay | 72 hrs | Cytotoxicity against human HeLa cells after 72 hrs by MTT assay, IC50 = 0.44 μM. | 19689125 | ||
| A549 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human A549 cells after 72 hrs by MTT assay, IC50 = 5.91 μM. | 19689125 | ||
| B16-BL6 | Cytotoxicity assay | 72 hrs | Cytotoxicity against mouse B16-BL6 cells after 72 hrs by MTT assay, IC50 = 7.39 μM. | 19689125 | ||
| HT1080 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human HT1080 cells after 72 hrs by MTT assay, IC50 = 8.58 μM. | 19689125 | ||
| OVCAR-3 | Anticancer assay | 48 hrs | Anticancer activity against human OVCAR-3 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.01585 μM. | 19740574 | ||
| SR | Anticancer assay | 48 hrs | Anticancer activity against human SR cells after 48 hrs by sulforhodamine B assay, GI50 = 0.02399 μM. | 19740574 | ||
| RPMI8266 | Anticancer assay | 48 hrs | Anticancer activity against human RPMI8266 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.04467 μM. | 19740574 | ||
| MALME-3M | Anticancer assay | 48 hrs | Anticancer activity against human MALME-3M cells after 48 hrs by sulforhodamine B assay, GI50 = 0.05129 μM. | 19740574 | ||
| HCC2998 | Anticancer assay | 48 hrs | Anticancer activity against human HCC2998 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.05248 μM. | 19740574 | ||
| NCI-H460 | Anticancer assay | 48 hrs | Anticancer activity against human NCI-H460 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.05623 μM. | 19740574 | ||
| SF539 | Anticancer assay | 48 hrs | Anticancer activity against human SF539 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.0631 μM. | 19740574 | ||
| Caki1 | Anticancer assay | 48 hrs | Anticancer activity against human Caki1 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.07244 μM. | 19740574 | ||
| MDA-MB-435 | Anticancer assay | 48 hrs | Anticancer activity against human MDA-MB-435 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.07244 μM. | 19740574 | ||
| MCF7 | Anticancer assay | 48 hrs | Anticancer activity against human MCF7 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.07943 μM. | 19740574 | ||
| HCT15 | Anticancer assay | 48 hrs | Anticancer activity against human HCT15 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.10965 μM. | 19740574 | ||
| COLO205 | Anticancer assay | 48 hrs | Anticancer activity against human COLO205 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.15849 μM. | 19740574 | ||
| NCI-H322M | Anticancer assay | 48 hrs | Anticancer activity against human NCI-H322M cells after 48 hrs by sulforhodamine B assay, GI50 = 0.17783 μM. | 19740574 | ||
| HT-29 | Anticancer assay | 48 hrs | Anticancer activity against human HT-29 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.17783 μM. | 19740574 | ||
| A549 | Anticancer assay | 48 hrs | Anticancer activity against human A549 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.19055 μM. | 19740574 | ||
| KM12 | Anticancer assay | 48 hrs | Anticancer activity against human KM12 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.2138 μM. | 19740574 | ||
| HCT116 | Anticancer assay | 48 hrs | Anticancer activity against human HCT116 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.22909 μM. | 19740574 | ||
| SF295 | Anticancer assay | 48 hrs | Anticancer activity against human SF295 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.22909 μM. | 19740574 | ||
| LOXIMVI | Anticancer assay | 48 hrs | Anticancer activity against human LOXIMVI cells after 48 hrs by sulforhodamine B assay, GI50 = 0.24547 μM. | 19740574 | ||
| ACHN | Anticancer assay | 48 hrs | Anticancer activity against human ACHN cells after 48 hrs by sulforhodamine B assay, GI50 = 0.29512 μM. | 19740574 | ||
| NCI/ADR-RES | Anticancer assay | 48 hrs | Anticancer activity against human NCI/ADR-RES cells after 48 hrs by sulforhodamine B assay, GI50 = 0.31623 μM. | 19740574 | ||
| NCI-H23 | Anticancer assay | 48 hrs | Anticancer activity against human NCI-H23 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.33113 μM. | 19740574 | ||
| MOLT4 | Anticancer assay | 48 hrs | Anticancer activity against human MOLT4 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.35481 μM. | 19740574 | ||
| DU145 | Anticancer assay | 48 hrs | Anticancer activity against human DU145 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.36308 μM. | 19740574 | ||
| HOP62 | Anticancer assay | 48 hrs | Anticancer activity against human HOP62 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.39811 μM. | 19740574 | ||
| A498 | Anticancer assay | 48 hrs | Anticancer activity against human A498 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.39811 μM. | 19740574 | ||
| SK-MEL-5 | Anticancer assay | 48 hrs | Anticancer activity against human SK-MEL-5 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.46774 μM. | 19740574 | ||
| SN12C | Anticancer assay | 48 hrs | Anticancer activity against human SN12C cells after 48 hrs by sulforhodamine B assay, GI50 = 0.50119 μM. | 19740574 | ||
| UACC62 | Anticancer assay | 48 hrs | Anticancer activity against human UACC62 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.52481 μM. | 19740574 | ||
| 786-0 | Anticancer assay | 48 hrs | Anticancer activity against human 786-0 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.72444 μM. | 19740574 | ||
| U251 | Anticancer assay | 48 hrs | Anticancer activity against human U251 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.91201 μM. | 19740574 | ||
| SW620 | Anticancer assay | 48 hrs | Anticancer activity against human SW620 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.93325 μM. | 19740574 | ||
| M14 | Anticancer assay | 48 hrs | Anticancer activity against human M14 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.97724 μM. | 19740574 | ||
| SK-MEL-28 | Anticancer assay | 48 hrs | Anticancer activity against human SK-MEL-28 cells after 48 hrs by sulforhodamine B assay, GI50 = 1.02329 μM. | 19740574 | ||
| TK10 | Anticancer assay | 48 hrs | Anticancer activity against human TK10 cells after 48 hrs by sulforhodamine B assay, GI50 = 1.12202 μM. | 19740574 | ||
| IGROV1 | Anticancer assay | 48 hrs | Anticancer activity against human IGROV1 cells after 48 hrs by sulforhodamine B assay, GI50 = 1.23027 μM. | 19740574 | ||
| UO31 | Anticancer assay | 48 hrs | Anticancer activity against human UO31 cells after 48 hrs by sulforhodamine B assay, GI50 = 1.41254 μM. | 19740574 | ||
| SF268 | Anticancer assay | 48 hrs | Anticancer activity against human SF268 cells after 48 hrs by sulforhodamine B assay, GI50 = 1.58489 μM. | 19740574 | ||
| OVCAR8 | Anticancer assay | 48 hrs | Anticancer activity against human OVCAR8 cells after 48 hrs by sulforhodamine B assay, GI50 = 1.7378 μM. | 19740574 | ||
| HL-60(TB) | Anticancer assay | 48 hrs | Anticancer activity against human HL-60(TB) cells after 48 hrs by sulforhodamine B assay, GI50 = 2.29087 μM. | 19740574 | ||
| PC3 | Anticancer assay | 48 hrs | Anticancer activity against human PC3 cells after 48 hrs by sulforhodamine B assay, GI50 = 2.34423 μM. | 19740574 | ||
| RXF393 | Anticancer assay | 48 hrs | Anticancer activity against human RXF393 cells after 48 hrs by sulforhodamine B assay, GI50 = 2.63027 μM. | 19740574 | ||
| K562 | Anticancer assay | 48 hrs | Anticancer activity against human K562 cells after 48 hrs by sulforhodamine B assay, GI50 = 3.54813 μM. | 19740574 | ||
| UACC257 | Anticancer assay | 48 hrs | Anticancer activity against human UACC257 cells after 48 hrs by sulforhodamine B assay, GI50 = 3.54813 μM. | 19740574 | ||
| SNB19 | Anticancer assay | 48 hrs | Anticancer activity against human SNB19 cells after 48 hrs by sulforhodamine B assay, GI50 = 3.80189 μM. | 19740574 | ||
| OVCAR4 | Anticancer assay | 48 hrs | Anticancer activity against human OVCAR4 cells after 48 hrs by sulforhodamine B assay, GI50 = 4.46684 μM. | 19740574 | ||
| MDA-MB-231 | Anticancer assay | 48 hrs | Anticancer activity against human MDA-MB-231 cells after 48 hrs by sulforhodamine B assay, GI50 = 6.60693 μM. | 19740574 | ||
| NCI-H522 | Anticancer assay | 48 hrs | Anticancer activity against human NCI-H522 cells after 48 hrs by sulforhodamine B assay, GI50 = 7.24436 μM. | 19740574 | ||
| T47D | Anticancer assay | 48 hrs | Anticancer activity against human T47D cells after 48 hrs by sulforhodamine B assay, GI50 = 8.12831 μM. | 19740574 | ||
| CCRF-CEM | Anticancer assay | 48 hrs | Anticancer activity against human CCRF-CEM cells after 48 hrs by sulforhodamine B assay, GI50 = 9.77237 μM. | 19740574 | ||
| Hs 578T | Anticancer assay | 48 hrs | Anticancer activity against human Hs 578T cells after 48 hrs by sulforhodamine B assay, GI50 = 9.77237 μM. | 19740574 | ||
| BT549 | Anticancer assay | 48 hrs | Anticancer activity against human BT549 cells after 48 hrs by sulforhodamine B assay, GI50 = 10.7152 μM. | 19740574 | ||
| OVCAR5 | Anticancer assay | 48 hrs | Anticancer activity against human OVCAR5 cells after 48 hrs by sulforhodamine B assay, GI50 = 10.9648 μM. | 19740574 | ||
| SKOV3 | Anticancer assay | 48 hrs | Anticancer activity against human SKOV3 cells after 48 hrs by sulforhodamine B assay, GI50 = 21.8776 μM. | 19740574 | ||
| MCF7 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay, IC50 = 0.3 μM. | 19743863 | ||
| T47D | Antiproliferative assay | 72 hrs | Antiproliferative activity against human T47D cells after 72 hrs by MTT assay, IC50 = 0.6 μM. | 19743863 | ||
| MES-SA | Antiproliferative assay | 72 hrs | Antiproliferative activity against human MES-SA cells after 72 hrs by MTT assay, IC50 = 1.1 μM. | 19743863 | ||
| SW480 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human SW480 cells after 72 hrs by MTT assay, IC50 = 2.1 μM. | 19743863 | ||
| HCT116 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay, IC50 = 2.6 μM. | 19743863 | ||
| UACC-812 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human UACC-812 cells after 72 hrs by MTT assay, IC50 = 3.1 μM. | 19743863 | ||
| RL | Antiproliferative assay | 72 hrs | Antiproliferative activity against human RL cells after 72 hrs by MTT assay, IC50 = 3.2 μM. | 19743863 | ||
| SW48 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human SW48 cells after 72 hrs by MTT assay, IC50 = 4.4 μM. | 19743863 | ||
| HeLa | Cytotoxicity assay | 48 hrs | Cytotoxicity against human HeLa cells after 48 hrs by MTT assay, IC50 = 10 μM. | 19795843 | ||
| MCF7 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay, IC50 = 15 μM. | 19795843 | ||
| KB | Cytotoxicity assay | 72 hrs | Cytotoxicity against human KB cells after 72 hrs MTT assay, IC50 = 12.5 μM. | 19846302 | ||
| HT1080 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human HT1080 cells after 72 hrs by MTT assay, IC50 = 5.2 μM. | 19919052 | ||
| HeLa | Cytotoxicity assay | 48 hrs | Cytotoxicity against human HeLa cells after 48 hrs by MTT assay, IC50 = 10 μM. | 19919065 | ||
| MCF7 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay, IC50 = 15 μM. | 19919065 | ||
| COLO205 | Growth inhibition assay | 48 hrs | Growth inhibition of human COLO205 cells after 48 hrs by sulforhodamine B assay, IC50 = 21 μM. | 19939522 | ||
| HCT116 | Cytotoxicity assay | 24 hrs | Cytotoxicity against human HCT116 cells after 24 hrs by trypan blue exclusion assay, IC50 = 3.03 μM. | 20163895 | ||
| MOLT4 | Antitumor assay | 24 hrs | Antitumor activity against human MOLT4 cells after 24 hrs by MTT assay, IC50 = 0.03 μM. | 20211564 | ||
| H460 | Antitumor assay | 24 hrs | Antitumor activity against human H460 cells after 24 hrs by MTT assay, IC50 = 2 μM. | 20211564 | ||
| HCT116 | Antitumor assay | 24 hrs | Antitumor activity against human HCT116 cells after 24 hrs by MTT assay, IC50 = 4 μM. | 20211564 | ||
| SW620 | Antitumor assay | 24 hrs | Antitumor activity against human SW620 cells after 24 hrs by MTT assay, IC50 = 9 μM. | 20211564 | ||
| MCF7 | Antitumor assay | 24 hrs | Antitumor activity against human MCF7 cells after 24 hrs by MTT assay, IC50 = 15 μM. | 20211564 | ||
| colon cancer | Antitumor assay | 48 hrs | Antitumor activity against human colon cancer cells after 48 hrs by SRB assay, GI50 = 8.4 μM. | 20350811 | ||
| leukemia | Antitumor assay | 48 hrs | Antitumor activity against human leukemia cells after 48 hrs by SRB assay, GI50 = 15.1 μM. | 20350811 | ||
| prostate cancer | Antitumor assay | 48 hrs | Antitumor activity against human prostate cancer cells after 48 hrs by SRB assay, GI50 = 22.7 μM. | 20350811 | ||
| renal cancer | Antitumor assay | 48 hrs | Antitumor activity against human renal cancer cells after 48 hrs by SRB assay, GI50 = 45.6 μM. | 20350811 | ||
| KB | Cytotoxicity assay | 3 days | Cytotoxicity against human KB cells after 3 days by MTT assay, IC50 = 4.46 μM. | 20356655 | ||
| NCI-H460 | Cytotoxicity assay | Cytotoxicity against human NCI-H460 cells, GI50 = 2.3 μM. | 20356752 | |||
| 3T3 | Cytotoxicity assay | Cytotoxicity against BALB mouse 3T3 cells, GI50 = 3 μM. | 20356752 | |||
| MCF7 | Cytotoxicity assay | Cytotoxicity against human MCF7 cells, GI50 = 4.5 μM. | 20356752 | |||
| DU145 | Cytotoxicity assay | Cytotoxicity against human DU145 cells, GI50 = 5.3 μM. | 20356752 | |||
| HT-29 | Cytotoxicity assay | Cytotoxicity against human HT-29 cells, GI50 = 14.9 μM. | 20356752 | |||
| M14 | Cytotoxicity assay | Cytotoxicity against human M14 cells, GI50 = 32.4 μM. | 20356752 | |||
| SFME | Antiproliferative assay | 24 hrs | Antiproliferative activity against mouse SFME cells after 24 hrs by MTT assay, IC50 = 3.2 μM. | 20398972 | ||
| r/m HM-SFME-1 | Antiproliferative assay | 24 hrs | Antiproliferative activity against mouse r/m HM-SFME-1 cells after 24 hrs by MTT assay, IC50 = 48.5 μM. | 20398972 | ||
| H460 | Antiproliferative assay | 24 hrs | Antiproliferative activity against human H460 cells after 24 hrs by trypan blue exclusion assay, IC50 = 2.7 μM. | 20403701 | ||
| MDA231 | Antiproliferative assay | 24 hrs | Antiproliferative activity against human MDA231 cells after 24 hrs by trypan blue exclusion assay, IC50 = 3.5 μM. | 20403701 | ||
| A549 | Antiproliferative assay | 24 hrs | Antiproliferative activity against human A549 cells after 24 hrs by trypan blue exclusion assay, IC50 = 5.4 μM. | 20403701 | ||
| MCF7 | Antiproliferative assay | 24 hrs | Antiproliferative activity against human MCF7 cells after 24 hrs by trypan blue exclusion assay, IC50 = 15.2 μM. | 20403701 | ||
| HeLa | Cytotoxicity assay | 48 hrs | Cytotoxicity against human HeLa cells after 48 hrs by MTT assay, IC50 = 10 μM. | 20405881 | ||
| SKBR3 | Antiproliferative assay | 48 hrs | Antiproliferative activity against estrogen receptor deficient human SKBR3 cells after 48 hrs by SRB assay, GI50 = 3 μM. | 20438092 | ||
| MCF7/BUS | Antiproliferative assay | 48 hrs | Antiproliferative activity against human MCF7/BUS cells expressing estrogen receptor after 48 hrs by SRB assay, GI50 = 6.2 μM. | 20438092 | ||
| MCF7 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human MCF7 cells expressing estrogen receptor after 48 hrs by SRB assay, GI50 = 8.3 μM. | 20438092 | ||
| T47D | Antiproliferative assay | 48 hrs | Antiproliferative activity against human T47D cells expressing estrogen receptor after 48 hrs by SRB assay, GI50 = 47 μM. | 20438092 | ||
| HCT116 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human HCT116 cells after 72 hrs by MTT assay, IC50 = 1.93 μM. | 20494492 | ||
| DU145 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human DU145 cells after 72 hrs by MTT assay, IC50 = 2.19 μM. | 20494492 | ||
| SGC7901 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human SGC7901 cells after 72 hrs by MTT assay, IC50 = 2.95 μM. | 20494492 | ||
| HeLa | Cytotoxicity assay | 72 hrs | Cytotoxicity against human HeLa cells after 72 hrs by MTT assay, IC50 = 9.7 μM. | 20494492 | ||
| K562 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human K562 cells after 72 hrs by MTT assay, IC50 = 45.4 μM. | 20494492 | ||
| OVCAR-3 | Growth inhibition assay | 48 hrs | Growth inhibition of human OVCAR-3 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.01585 μM. | 20850204 | ||
| SR | Growth inhibition assay | 48 hrs | Growth inhibition of human SR cells after 48 hrs by sulforhodamine B assay, GI50 = 0.02399 μM. | 20850204 | ||
| RPMI8266 | Growth inhibition assay | 48 hrs | Growth inhibition of human RPMI8266 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.04467 μM. | 20850204 | ||
| MALME-3M | Growth inhibition assay | 48 hrs | Growth inhibition of human MALME-3M cells after 48 hrs by sulforhodamine B assay, GI50 = 0.05129 μM. | 20850204 | ||
| HCC2998 | Growth inhibition assay | 48 hrs | Growth inhibition of human HCC2998 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.05248 μM. | 20850204 | ||
| NCI-H460 | Growth inhibition assay | 48 hrs | Growth inhibition of human NCI-H460 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.05623 μM. | 20850204 | ||
| SF539 | Growth inhibition assay | 48 hrs | Growth inhibition of human SF539 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.0631 μM. | 20850204 | ||
| Caki1 | Growth inhibition assay | 48 hrs | Growth inhibition of human Caki1 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.07244 μM. | 20850204 | ||
| MDA-MB-435 | Growth inhibition assay | 48 hrs | Growth inhibition of human MDA-MB-435 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.07244 μM. | 20850204 | ||
| MCF7 | Growth inhibition assay | 48 hrs | Growth inhibition of human MCF7 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.07943 μM. | 20850204 | ||
| HCT15 | Growth inhibition assay | 48 hrs | Growth inhibition of human HCT15 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.10965 μM. | 20850204 | ||
| COLO205 | Growth inhibition assay | 48 hrs | Growth inhibition of human COLO205 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.15849 μM. | 20850204 | ||
| HT-29 | Growth inhibition assay | 48 hrs | Growth inhibition of human HT-29 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.17783 μM. | 20850204 | ||
| NCI-H322M | Growth inhibition assay | 48 hrs | Growth inhibition of human NCI-H322M cells after 48 hrs by sulforhodamine B assay, GI50 = 0.17783 μM. | 20850204 | ||
| A549 | Growth inhibition assay | 48 hrs | Growth inhibition of human A549 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.19055 μM. | 20850204 | ||
| KM12 | Growth inhibition assay | 48 hrs | Growth inhibition of human KM12 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.2138 μM. | 20850204 | ||
| HCT116 | Growth inhibition assay | 48 hrs | Growth inhibition of human HCT116 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.22909 μM. | 20850204 | ||
| SF295 | Growth inhibition assay | 48 hrs | Growth inhibition of human SF295 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.22909 μM. | 20850204 | ||
| LOXIMVI | Growth inhibition assay | 48 hrs | Growth inhibition of human LOXIMVI cells after 48 hrs by sulforhodamine B assay, GI50 = 0.24547 μM. | 20850204 | ||
| ACHN | Growth inhibition assay | 48 hrs | Growth inhibition of human ACHN cells after 48 hrs by sulforhodamine B assay, GI50 = 0.29512 μM. | 20850204 | ||
| NCI/ADR-RES | Growth inhibition assay | 48 hrs | Growth inhibition of human NCI/ADR-RES cells after 48 hrs by sulforhodamine B assay, GI50 = 0.31623 μM. | 20850204 | ||
| NCI-H23 | Growth inhibition assay | 48 hrs | Growth inhibition of human NCI-H23 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.33113 μM. | 20850204 | ||
| MOLT4 | Growth inhibition assay | 48 hrs | Growth inhibition of human MOLT4 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.35481 μM. | 20850204 | ||
| DU145 | Growth inhibition assay | 48 hrs | Growth inhibition of human DU145 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.36308 μM. | 20850204 | ||
| HOP62 | Growth inhibition assay | 48 hrs | Growth inhibition of human HOP62 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.39811 μM. | 20850204 | ||
| A498 | Growth inhibition assay | 48 hrs | Growth inhibition of human A498 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.39811 μM. | 20850204 | ||
| SK-MEL-5 | Growth inhibition assay | 48 hrs | Growth inhibition of human SK-MEL-5 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.46774 μM. | 20850204 | ||
| SN12C | Growth inhibition assay | 48 hrs | Growth inhibition of human SN12C cells after 48 hrs by sulforhodamine B assay, GI50 = 0.50119 μM. | 20850204 | ||
| UACC62 | Growth inhibition assay | 48 hrs | Growth inhibition of human UACC62 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.52481 μM. | 20850204 | ||
| 786-0 | Growth inhibition assay | 48 hrs | Growth inhibition of human 786-0 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.72444 μM. | 20850204 | ||
| U251 | Growth inhibition assay | 48 hrs | Growth inhibition of human U251 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.91201 μM. | 20850204 | ||
| SW620 | Growth inhibition assay | 48 hrs | Growth inhibition of human SW620 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.93325 μM. | 20850204 | ||
| M14 | Growth inhibition assay | 48 hrs | Growth inhibition of human M14 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.97724 μM. | 20850204 | ||
| SK-MEL-28 | Growth inhibition assay | 48 hrs | Growth inhibition of human SK-MEL-28 cells after 48 hrs by sulforhodamine B assay, GI50 = 1.02329 μM. | 20850204 | ||
| TK10 | Growth inhibition assay | 48 hrs | Growth inhibition of human TK10 cells after 48 hrs by sulforhodamine B assay, GI50 = 1.12202 μM. | 20850204 | ||
| IGROV1 | Growth inhibition assay | 48 hrs | Growth inhibition of human IGROV1 cells after 48 hrs by sulforhodamine B assay, GI50 = 1.23027 μM. | 20850204 | ||
| UO31 | Growth inhibition assay | 48 hrs | Growth inhibition of human UO31 cells after 48 hrs by sulforhodamine B assay, GI50 = 1.41254 μM. | 20850204 | ||
| SF268 | Growth inhibition assay | 48 hrs | Growth inhibition of human SF268 cells after 48 hrs by sulforhodamine B assay, GI50 = 1.58489 μM. | 20850204 | ||
| OVCAR8 | Growth inhibition assay | 48 hrs | Growth inhibition of human OVCAR8 cells after 48 hrs by sulforhodamine B assay, GI50 = 1.7378 μM. | 20850204 | ||
| HL-60(TB) | Growth inhibition assay | 48 hrs | Growth inhibition of human HL-60(TB) cells after 48 hrs by sulforhodamine B assay, GI50 = 2.29087 μM. | 20850204 | ||
| PC3 | Growth inhibition assay | 48 hrs | Growth inhibition of human PC3 cells after 48 hrs by sulforhodamine B assay, GI50 = 2.34423 μM. | 20850204 | ||
| RXF393 | Growth inhibition assay | 48 hrs | Growth inhibition of human RXF393 cells after 48 hrs by sulforhodamine B assay, GI50 = 2.63027 μM. | 20850204 | ||
| K562 | Growth inhibition assay | 48 hrs | Growth inhibition of human K562 cells after 48 hrs by sulforhodamine B assay, GI50 = 3.54813 μM. | 20850204 | ||
| UACC257 | Growth inhibition assay | 48 hrs | Growth inhibition of human UACC257 cells after 48 hrs by sulforhodamine B assay, GI50 = 3.54813 μM. | 20850204 | ||
| SNB19 | Growth inhibition assay | 48 hrs | Growth inhibition of human SNB19 cells after 48 hrs by sulforhodamine B assay, GI50 = 3.80189 μM. | 20850204 | ||
| OVCAR4 | Growth inhibition assay | 48 hrs | Growth inhibition of human OVCAR4 cells after 48 hrs by sulforhodamine B assay, GI50 = 4.46684 μM. | 20850204 | ||
| MDA-MB-231 | Growth inhibition assay | 48 hrs | Growth inhibition of human MDA-MB-231 cells after 48 hrs by sulforhodamine B assay, GI50 = 6.60693 μM. | 20850204 | ||
| NCI-H522 | Growth inhibition assay | 48 hrs | Growth inhibition of human NCI-H522 cells after 48 hrs by sulforhodamine B assay, GI50 = 7.24436 μM. | 20850204 | ||
| T47D | Growth inhibition assay | 48 hrs | Growth inhibition of human T47D cells after 48 hrs by sulforhodamine B assay, GI50 = 8.12831 μM. | 20850204 | ||
| CCRF-CEM | Growth inhibition assay | 48 hrs | Growth inhibition of human CCRF-CEM cells after 48 hrs by sulforhodamine B assay, GI50 = 9.77237 μM. | 20850204 | ||
| Hs 578T | Growth inhibition assay | 48 hrs | Growth inhibition of human Hs 578T cells after 48 hrs by sulforhodamine B assay, GI50 = 9.77237 μM. | 20850204 | ||
| BT549 | Growth inhibition assay | 48 hrs | Growth inhibition of human BT549 cells after 48 hrs by sulforhodamine B assay, GI50 = 10.7152 μM. | 20850204 | ||
| OVCAR5 | Growth inhibition assay | 48 hrs | Growth inhibition of human OVCAR5 cells after 48 hrs by sulforhodamine B assay, GI50 = 10.9648 μM. | 20850204 | ||
| SKOV3 | Growth inhibition assay | 48 hrs | Growth inhibition of human SKOV3 cells after 48 hrs by sulforhodamine B assay, GI50 = 21.8776 μM. | 20850204 | ||
| HCT116 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human HCT116 cells expressing p53 after 72 hrs by celltiter-glo assay, IC50 = 12 μM. | 20873740 | ||
| A2780 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human A2780 cells expressing p53 after 72 hrs by celltiter-glo assay, IC50 = 14 μM. | 20873740 | ||
| U2OS | Antiproliferative assay | 72 hrs | Antiproliferative activity against human U2OS cells expressing p53 after 72 hrs by celltiter-glo assay, IC50 = 16 μM. | 20873740 | ||
| p53 deficient PC3 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human p53 deficient PC3 cells after 72 hrs by celltiter-glo assay, IC50 = 30 μM. | 20873740 | ||
| SF539 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human SF539 cells expressing p53 after 72 hrs by celltiter-glo assay, IC50 = 43 μM. | 20873740 | ||
| HCT15 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human HCT15 cells expressing p53 after 72 hrs by celltiter-glo assay, IC50 = 48 μM. | 20873740 | ||
| T3M4 | Cytotoxicity assay | Cytotoxicity against human T3M4 cells by crystal violet staining, IC50 = 0.33 μM. | 20930123 | |||
| Colo-357 | Cytotoxicity assay | Cytotoxicity against human Colo-357 cells by crystal violet staining, IC50 = 2.05 μM. | 20930123 | |||
| Patu-T | Cytotoxicity assay | Cytotoxicity against human Patu-T cells by crystal violet staining, IC50 = 2.08 μM. | 20930123 | |||
| Patu-S | Cytotoxicity assay | Cytotoxicity against human Patu-S cells by crystal violet staining, IC50 = 2.93 μM. | 20930123 | |||
| Aspc-1 | Cytotoxicity assay | Cytotoxicity against human Aspc-1 cells by crystal violet staining, IC50 = 2.97 μM. | 20930123 | |||
| PANC1 | Cytotoxicity assay | Cytotoxicity against human PANC1 cells by crystal violet staining, IC50 = 3.94 μM. | 20930123 | |||
| Patu-02 | Cytotoxicity assay | Cytotoxicity against human Patu-02 cells by crystal violet staining, IC50 = 3.95 μM. | 20930123 | |||
| DAN-G | Cytotoxicity assay | Cytotoxicity against human DAN-G cells by crystal violet staining, IC50 = 4.38 μM. | 20930123 | |||
| Patu-T | Cytotoxicity assay | Cytotoxicity against human 5-FU-resistant Patu-T cells by crystal violet staining, IC50 = 33.2 μM. | 20930123 | |||
| Hep2 | Anticancer assay | 48 hrs | Anticancer activity against human Hep2 cells assessed as cell viability after 48 hrs by SRB assay, IC50 = 0.3 μM. | 21074444 | ||
| A549 | Anticancer assay | 48 hrs | Anticancer activity against human A549 cells assessed as cell viability after 48 hrs by SRB assay, IC50 = 2.4 μM. | 21074444 | ||
| HCT15 | Anticancer assay | 48 hrs | Anticancer activity against human HCT15 cells assessed as cell viability after 48 hrs by SRB assay, IC50 = 3.6 μM. | 21074444 | ||
| 502713 | Anticancer assay | 48 hrs | Anticancer activity against human 502713 cells assessed as cell viability after 48 hrs by SRB assay, IC50 = 4.6 μM. | 21074444 | ||
| DU145 | Anticancer assay | 48 hrs | Anticancer activity against human DU145 cells assessed as cell viability after 48 hrs by SRB assay, IC50 = 4.8 μM. | 21074444 | ||
| PC3 | Anticancer assay | 48 hrs | Anticancer activity against human PC3 cells assessed as cell viability after 48 hrs by SRB assay, IC50 = 12 μM. | 21074444 | ||
| IMR32 | Anticancer assay | 48 hrs | Anticancer activity against human IMR32 cells assessed as cell viability after 48 hrs by SRB assay, IC50 = 18 μM. | 21074444 | ||
| MCF7 | Cytotoxicity assay | 3 days | Cytotoxicity against human MCF7 cells expressing wild type p53 and ras mutant after 3 days by SRB assay, IC50 = 4.32 μM. | 21126804 | ||
| KB | Cytotoxicity assay | 48 hrs | Cytotoxicity against human KB cells after 48 hrs by MTT assay, IC50 = 2.16 μM. | 21131104 | ||
| HepG2 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay, IC50 = 2.78 μM. | 21131104 | ||
| K562 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human K562 cells after 48 hrs by MTT assay, IC50 = 38 μM. | 21131104 | ||
| KB | Cytotoxicity assay | 3 days | Cytotoxicity against human KB cells after 3 days by MTT assay, IC50 = 11.9 μM. | 21144621 | ||
| MGC803 | Cytotoxicity assay | 3 days | Cytotoxicity against human MGC803 cells after 3 days by MTT assay, IC50 = 12.6 μM. | 21144621 | ||
| CNE2 | Cytotoxicity assay | 3 days | Cytotoxicity against human CNE2 cells after 3 days by MTT assay, IC50 = 13.1 μM. | 21144621 | ||
| MCF7 | Cytotoxicity assay | 3 days | Cytotoxicity against human MCF7 cells after 3 days by MTT assay, IC50 = 15.2 μM. | 21144621 | ||
| L1210 | Cytotoxicity assay | 2 days | Cytotoxicity against mouse L1210 cells after 2 days by coulter counter analysis, IC50 = 0.56 μM. | 21232828 | ||
| HeLa | Cytotoxicity assay | 4 days | Cytotoxicity against human HeLa cells after 4 days by coulter counter analysis, IC50 = 0.57 μM. | 21232828 | ||
| CEM | Cytotoxicity assay | 3 days | Cytotoxicity against human CEM cells after 3 days by coulter counter analysis, IC50 = 14 μM. | 21232828 | ||
| HL60 | Cytotoxicity assay | 48 hrs | Cytotoxicity in human HL60 cells assessed as cell viability after 48 hrs by MTT assay, IC50 = 9.5 μM. | 21250700 | ||
| A549 | Cytotoxicity assay | 48 hrs | Cytotoxicity in human A549 cells assessed as cell viability after 48 hrs by MTT assay, IC50 = 11.3 μM. | 21250700 | ||
| KB | Cytotoxicity assay | 72 hrs | Cytotoxicity against human KB cells after 72 hrs by MTT assay, IC50 = 15.9 μM. | 21273072 | ||
| MDA-MB-231 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human MDA-MB-231 cells assessed as growth inhibition after 72 hrs, IC50 = 4.7 μM. | 21295381 | ||
| MCF7 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human MCF7 cells assessed as growth inhibition after 72 hrs, IC50 = 9.6 μM. | 21295381 | ||
| L1210 | Function assay | 24 hrs | Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxyuridine after preincubation for 24 hrs by liquid scintillation counting, IC50 = 0.02 μM. | 21330014 | ||
| L1210 | Function assay | 24 hrs | Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxycytidine after preincubation for 24 hrs by liquid scintillation counting, IC50 = 0.06 μM. | 21330014 | ||
| FM3A | Cytostatic activity assay | 2 days | Cytostatic activity against mouse FM3A cells after 2 days by coulter counting analysis, IC50 = 0.18 μM. | 21330014 | ||
| HeLa | Cytostatic activity assay | Cytostatic activity against human HeLa cells in presence of 20 uM 2'-deoxyuridine, IC50 = 0.18 μM. | 21330014 | |||
| L1210 | Function assay | 4 hrs | Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxyuridine after preincubation for 4 hrs by liquid scintillation counting, IC50 = 0.22 μM. | 21330014 | ||
| L1210 | Function assay | 24 hrs | Inhibition of DNA synthesis in mouse L1210 cells assessed as [6-3H]2'-deoxyuridine incorporation in to DNA preincubated for 24 hrs by liquid scintillation counting, IC50 = 0.37 μM. | 21330014 | ||
| HeLa | Cytostatic activity assay | 3 days | Cytostatic activity against human HeLa cells after 3 days by coulter counting analysis, IC50 = 0.45 μM. | 21330014 | ||
| L1210 | Cytostatic activity assay | Cytostatic activity against mouse L1210 cells in presence of 500 uM uracil, IC50 = 0.47 μM. | 21330014 | |||
| L1210 | Cytostatic activity assay | 2 days | Cytostatic activity against mouse L1210 cells after 2 days by coulter counting analysis, IC50 = 0.56 μM. | 21330014 | ||
| L1210 | Function assay | 4 hrs | Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxycytidine after preincubation for 4 hrs by liquid scintillation counting, IC50 = 0.6 μM. | 21330014 | ||
| L1210 | Cytostatic activity assay | Cytostatic activity against mouse L1210 cells in presence of 500 uM uridine, IC50 = 0.62 μM. | 21330014 | |||
| L1210 | Function assay | Inhibition of DNA synthesis in mouse L1210 cells assessed as [6-3H]2'-deoxyuridine incorporation in to DNA by liquid scintillation counting, IC50 = 0.97 μM. | 21330014 | |||
| HeLa | Cytostatic activity assay | Cytostatic activity against human HeLa cells in presence of 500 uM uracil, IC50 = 1 μM. | 21330014 | |||
| HeLa | Cytostatic activity assay | Cytostatic activity against human HeLa cells in presence of 500 uM uridine, IC50 = 1.1 μM. | 21330014 | |||
| L1210 | Cytostatic activity assay | Cytostatic activity against mouse L1210 cells in presence of 20 uM 2'-deoxyuridine, IC50 = 1.3 μM. | 21330014 | |||
| HeLa | Cytostatic activity assay | Cytostatic activity against human HeLa cells in presence of 20 uM thymidine, IC50 = 1.5 μM. | 21330014 | |||
| L1210 | Function assay | 24 hrs | Inhibition of RNA synthesis in mouse L1210 cells assessed as [5-3H]uridine incorporation in to RNA preincubated for 24 hrs by liquid scintillation counting, IC50 = 4.9 μM. | 21330014 | ||
| L1210 | Function assay | 15 mins | Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxyuridine after preincubation for 15 mins by liquid scintillation counting, IC50 = 7 μM. | 21330014 | ||
| CEM | Cytostatic activity assay | 3 days | Cytostatic activity against human CEM cells after 3 days by coulter counting analysis, IC50 = 14 μM. | 21330014 | ||
| L1210 | Cytostatic activity assay | Cytostatic activity against mouse L1210 cells in presence of 20 uM thymidine, IC50 = 21 μM. | 21330014 | |||
| HL60 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human HL60 cells assessed as cell viability after 48 hrs by MTT assay, IC50 = 9.1 μM. | 21381696 | ||
| CEM | Cytotoxicity assay | 72 hrs | Cytotoxicity against human CEM cells after 72 hrs by trypan blue assay, IC50 = 8 μM. | 21439690 | ||
| CEM | Cytotoxicity assay | 48 hrs | Cytotoxicity against human CEM cells after 48 hrs by trypan blue assay, IC50 = 15 μM. | 21439690 | ||
| CEM | Cytotoxicity assay | 72 hrs | Cytotoxicity against human CEM cells after 72 hrs by MTT assay, IC50 = 30 μM. | 21439690 | ||
| CEM | Cytotoxicity assay | 48 hrs | Cytotoxicity against human CEM cells after 48 hrs by MTT assay, IC50 = 40 μM. | 21439690 | ||
| K562 | Anticancer assay | Anticancer activity against human K562 cells, IC50 = 2.4 μM. | 21449610 | |||
| COLO205 | Anticancer assay | Anticancer activity against human COLO205 cells, IC50 = 4.17 μM. | 21449610 | |||
| KM12 | Anticancer assay | Anticancer activity against human KM12 cells, IC50 = 8.32 μM. | 21449610 | |||
| HCT116 | Anticancer assay | Anticancer activity against human HCT116 cells, IC50 = 8.51 μM. | 21449610 | |||
| HCT15 | Anticancer assay | Anticancer activity against human HCT15 cells, IC50 = 9.71 μM. | 21449610 | |||
| HT-29 | Anticancer assay | Anticancer activity against human HT-29 cells, IC50 = 10.2 μM. | 21449610 | |||
| HCC2998 | Anticancer assay | Anticancer activity against human HCC2998 cells, IC50 = 13.5 μM. | 21449610 | |||
| CCRF-CEM | Anticancer assay | Anticancer activity against human CCRF-CEM cells, IC50 = 33.1 μM. | 21449610 | |||
| MIAPaCa2 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human MIAPaCa2 cells after 72 hrs, IC50 = 7.4 μM. | 21458113 | ||
| COLO320 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human COLO320 cells after 72 hrs, IC50 = 8.7 μM. | 21458113 | ||
| COLO320 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human COLO320 cells after 48 hrs, IC50 = 10 μM. | 21458113 | ||
| MIAPaCa2 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human MIAPaCa2 cells after 48 hrs, IC50 = 14 μM. | 21458113 | ||
| MCF7 | Antitumor assay | 72 hrs | Antitumor activity against human MCF7 cells after 72 hrs by MTT assay, IC50 = 7.54 μM. | 21486694 | ||
| EC9706 | Antitumor assay | 72 hrs | Antitumor activity against human EC9706 cells after 72 hrs by MTT assay, IC50 = 20.3 μM. | 21486694 | ||
| SPC-A1 | Antitumor assay | 72 hrs | Antitumor activity against human SPC-A1 cells after 72 hrs by MTT assay, IC50 = 26.92 μM. | 21486694 | ||
| PC3 | Antitumor assay | 72 hrs | Antitumor activity against human PC3 cells after 72 hrs by MTT assay, IC50 = 29.3 μM. | 21486694 | ||
| HeLa | Antitumor assay | 72 hrs | Antitumor activity against human HeLa cells after 72 hrs by MTT assay, IC50 = 41.46 μM. | 21486694 | ||
| ZR-75-1 | Growth inhibition assay | 48 hrs | Growth inhibition of human ZR-75-1 cells after 48 hrs by sulforhodamine B assay, GI50 = 2.3 μM. | 21489802 | ||
| A549 | Growth inhibition assay | 48 hrs | Growth inhibition of human A549 cells after 48 hrs by sulforhodamine B assay, GI50 = 2.4 μM. | 21489802 | ||
| COLO205 | Growth inhibition assay | 48 hrs | Growth inhibition of human COLO205 cells after 48 hrs by sulforhodamine B assay, GI50 = 2.8 μM. | 21489802 | ||
| MCF7 | Growth inhibition assay | 48 hrs | Growth inhibition of human MCF7 cells after 48 hrs by sulforhodamine B assay, GI50 = 2.8 μM. | 21489802 | ||
| Gurav | Growth inhibition assay | 48 hrs | Growth inhibition of human Gurav cells after 48 hrs by sulforhodamine B assay, GI50 = 3.1 μM. | 21489802 | ||
| A2780 | Growth inhibition assay | 48 hrs | Growth inhibition of human A2780 cells after 48 hrs by sulforhodamine B assay, GI50 = 3.5 μM. | 21489802 | ||
| HOP62 | Growth inhibition assay | 48 hrs | Growth inhibition of human HOP62 cells after 48 hrs by sulforhodamine B assay, GI50 = 4.1 μM. | 21489802 | ||
| KB | Growth inhibition assay | 48 hrs | Growth inhibition of human KB cells after 48 hrs by sulforhodamine B assay, GI50 = 5.2 μM. | 21489802 | ||
| DWD | Growth inhibition assay | 48 hrs | Growth inhibition of human DWD cells after 48 hrs by sulforhodamine B assay, GI50 = 6.1 μM. | 21489802 | ||
| SiHa | Growth inhibition assay | 48 hrs | Growth inhibition of human SiHa cells after 48 hrs by sulforhodamine B assay, GI50 = 6.3 μM. | 21489802 | ||
| PC3 | Growth inhibition assay | 48 hrs | Growth inhibition of human PC3 cells after 48 hrs by sulforhodamine B assay, GI50 = 12 μM. | 21489802 | ||
| SMMC7721 | Cytotoxicity assay | Cytotoxicity against human SMMC7721 cells, IC50 = 13 μM. | 21495659 | |||
| A549 | Cytotoxicity assay | Cytotoxicity against human A549 cells, IC50 = 13.7 μM. | 21495659 | |||
| Bel7402 | Cytotoxicity assay | Cytotoxicity against human Bel7402 cells, IC50 = 21.8 μM. | 21495659 | |||
| A549 | Cytotoxicity assay | Cytotoxicity against human A549 cells by MTT assay, IC50 = 5.6 μM. | 21515044 | |||
| QGY | Cytotoxicity assay | Cytotoxicity against human QGY cells by MTT assay, IC50 = 14.1 μM. | 21515044 | |||
| HeLa | Cytotoxicity assay | Cytotoxicity against human HeLa cells by MTT assay, IC50 = 16.1 μM. | 21515044 | |||
| SW620 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human SW620 cells after 72 hrs by MTT assay, IC50 = 3.38 μM. | 21524829 | ||
| HeLa | Antiproliferative assay | 72 hrs | Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay, IC50 = 10.31 μM. | 21524829 | ||
| MIAPaCa2 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human MIAPaCa2 cells after 72 hrs by MTT assay, IC50 = 11.45 μM. | 21524829 | ||
| WI38 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human WI38 cells after 72 hrs by MTT assay, IC50 = 18.5 μM. | 21524829 | ||
| SKBR3 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human SKBR3 cells after 72 hrs by MTT assay, IC50 = 38.25 μM. | 21524829 | ||
| MCF7 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay, IC50 = 42.01 μM. | 21524829 | ||
| PA1 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human PA1 cells after 48 hrs by resazurin reduction test, IC50 = 5 μM. | 21530016 | ||
| MCF7 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human MCF7 cells after 48 hrs by resazurin reduction test, IC50 = 15 μM. | 21530016 | ||
| HeLa | Cytotoxicity assay | 3 days | Cytotoxicity against human HeLa cells after 3 days by MTT assay, IC50 = 4 μM. | 21612935 | ||
| MG63 | Cytotoxicity assay | 3 days | Cytotoxicity against human MG63 cells after 3 days by MTT assay, IC50 = 8 μM. | 21612935 | ||
| L1210 | Cytotoxicity assay | 72 hrs | Cytotoxicity against mouse L1210 cells after 72 hrs by MTT assay, IC50 = 0.0000011 μM. | 21640594 | ||
| P388 | Cytotoxicity assay | 72 hrs | Cytotoxicity against mouse P388 cells after 72 hrs by MTT assay, IC50 = 0.0000017 μM. | 21640594 | ||
| HL60 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human HL60 cells after 72 hrs by MTT assay, IC50 = 0.0000027 μM. | 21640594 | ||
| KB | Cytotoxicity assay | 72 hrs | Cytotoxicity against human KB cells after 72 hrs by MTT assay, IC50 = 0.0000077 μM. | 21640594 | ||
| IEC-6 | Cytotoxicity assay | 6 days | Cytotoxicity against rat IEC-6 cells after 6 days by SRB colorimetric assay, IC50 = 0.66 μM. | 21684047 | ||
| MCF10A | Cytotoxicity assay | 6 days | Cytotoxicity against human MCF10A cells after 6 days by SRB colorimetric assay, IC50 = 0.73 μM. | 21684047 | ||
| HT-29 | Cytotoxicity assay | 6 days | Cytotoxicity against human HT-29 cells after 6 days by SRB colorimetric assay, IC50 = 1.08 μM. | 21684047 | ||
| MCF7 | Cytotoxicity assay | 6 days | Cytotoxicity against human MCF7 cells after 6 days by SRB colorimetric assay, IC50 = 4.32 μM. | 21684047 | ||
| DU145 | Cytotoxicity assay | Cytotoxicity against human DU145 cells, IC50 = 3.3 μM. | 21774474 | |||
| NCI-H460 | Cytotoxicity assay | Cytotoxicity against human NCI-H460 cells, IC50 = 8.5 μM. | 21774474 | |||
| MCF7 | Cytotoxicity assay | Cytotoxicity against human MCF7 cells, IC50 = 31 μM. | 21774474 | |||
| KB | Cytotoxicity assay | 3 days | Cytotoxicity against human KB cells after 3 days by MTT assay, IC50 = 12.5 μM. | 21843939 | ||
| HeLa | Cytostatic activity assay | 72 hrs | Cytostatic activity against thymidine-kinase deficient human HeLa cells after 72 hrs by cell counting, IC50 = 0.23 μM. | 21892829 | ||
| L1210 | Cytostatic activity assay | 48 hrs | Cytostatic activity against thymidine-kinase deficient mouse L1210 cells after 48 hrs by cell counting, IC50 = 0.32 μM. | 21892829 | ||
| HeLa | Cytostatic activity assay | 72 hrs | Cytostatic activity against human HeLa cells after 72 hrs by cell counting, IC50 = 0.54 μM. | 21892829 | ||
| CEM | Cytostatic activity assay | 72 hrs | Cytostatic activity against thymidine-kinase deficient human CEM cells after 72 hrs by cell counting, IC50 = 12 μM. | 21892829 | ||
| CEM/0 | Cytostatic activity assay | 72 hrs | Cytostatic activity against human CEM/0 cells after 72 hrs by cell counting, IC50 = 18 μM. | 21892829 | ||
| L1210 | Cytostatic activity assay | Cytostatic activity against mouse L1210 cells, IC50 = 0.49 μM. | 21917363 | |||
| HeLa | Cytostatic activity assay | Cytostatic activity against human HeLa cells, IC50 = 0.54 μM. | 21917363 | |||
| CEM | Cytostatic activity assay | Cytostatic activity against human CEM cells, IC50 = 18 μM. | 21917363 | |||
| A549 | Cytotoxicity assay | 3 days | Cytotoxicity against human A549 cells after 3 days by MTT assay, IC50 = 0.42 μM. | 22000925 | ||
| HepG2 | Cytotoxicity assay | 3 days | Cytotoxicity against human HepG2 cells after 3 days by MTT assay, IC50 = 2.7 μM. | 22000925 | ||
| BCG823 | Cytotoxicity assay | 3 days | Cytotoxicity against human BCG823 cells after 3 days by MTT assay, IC50 = 6.15 μM. | 22000925 | ||
| colon cancer cell | Cytotoxicity assay | 48 hrs | Cytotoxicity against human colon cancer cells after 48 hrs by coulter counting, GI50 = 8.4 μM. | 22056277 | ||
| leukemia cell | Cytotoxicity assay | 48 hrs | Cytotoxicity against human leukemia cells after 48 hrs by coulter counting, GI50 = 15.1 μM. | 22056277 | ||
| prostate cancer cell | Cytotoxicity assay | 48 hrs | Cytotoxicity against human prostate cancer cells after 48 hrs by coulter counting, GI50 = 22.7 μM. | 22056277 | ||
| renal cancer cell | Cytotoxicity assay | 48 hrs | Cytotoxicity against human renal cancer cells after 48 hrs by coulter counting, GI50 = 45.6 μM. | 22056277 | ||
| MCF7 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay, IC50 = 9.67 μM. | 22079378 | ||
| KB | Antiproliferative assay | 72 hrs | Antiproliferative activity against human KB cells after 72 hrs by MTT assay, IC50 = 9.85 μM. | 22079378 | ||
| GLC82 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human GLC82 cells after 72 hrs by MTT assay, IC50 = 15.5 μM. | 22079378 | ||
| MGC803 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay, IC50 = 16.6 μM. | 22079378 | ||
| CNE2 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human CNE2 cells after 72 hrs by MTT assay, IC50 = 17.2 μM. | 22079378 | ||
| HEK293 | Cytotoxicity assay | 2 days | Cytotoxicity against human HEK293 cells after 2 days by alamar blue assay, IC50 = 42.9 μM. | 22093761 | ||
| colon cancer cell | Growth inhibition assay | 48 hrs | Growth inhibition of human colon cancer cells after 48 hrs by coulter counter method, GI50 = 8.4 μM. | 22119151 | ||
| leukemia cell | Growth inhibition assay | 48 hrs | Growth inhibition of human leukemia cells after 48 hrs by coulter counter method, GI50 = 15.1 μM. | 22119151 | ||
| prostate cancer cell | Growth inhibition assay | 48 hrs | Growth inhibition of human prostate cancer cells after 48 hrs by coulter counter method, GI50 = 22.7 μM. | 22119151 | ||
| renal cancer cell | Growth inhibition assay | 48 hrs | Growth inhibition of human renal cancer cells after 48 hrs by coulter counter method, GI50 = 45.6 μM. | 22119151 | ||
| H460 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human H460 cells after 72 hrs by MTT assay, IC50 = 3 μM. | 22130132 | ||
| HCT116 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human HCT116 cells after 72 hrs by MTT assay, IC50 = 4 μM. | 22130132 | ||
| MCF7 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay, IC50 = 14 μM. | 22130132 | ||
| A549 | Cytotoxicity assay | 24 hrs | Cytotoxicity against human A549 cells after 24 hrs by MTT assay, IC50 = 5.64 μM. | 22182926 | ||
| QGY7701 | Cytotoxicity assay | 24 hrs | Cytotoxicity against human QGY7701 cells after 24 hrs by MTT assay, IC50 = 14.3 μM. | 22182926 | ||
| SW480 | Cytotoxicity assay | 24 hrs | Cytotoxicity against human SW480 cells after 24 hrs by MTT assay, IC50 = 15.71 μM. | 22182926 | ||
| HeLa | Cytotoxicity assay | 24 hrs | Cytotoxicity against human HeLa cells after 24 hrs by MTT assay, IC50 = 16.32 μM. | 22182926 | ||
| KB | Cytotoxicity assay | 72 hrs | Cytotoxicity against human KB cells after 72 hrs ny MTT assay, IC50 = 9 μM. | 22200404 | ||
| CNE2 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human CNE2 cells after 72 hrs ny MTT assay, IC50 = 13.5 μM. | 22200404 | ||
| HepG2 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay, IC50 = 15.92 μM. | 22209486 | ||
| NCI-H460 | Cytotoxicity assay | Cytotoxicity against human NCI-H460 cells, IC50 = 8 μM. | 22283451 | |||
| SMMC7721 | Cytotoxicity assay | Cytotoxicity against human SMMC7721 cells, IC50 = 15 μM. | 22283451 | |||
| MCF7 | Cytotoxicity assay | Cytotoxicity against human MCF7 cells, IC50 = 31 μM. | 22283451 | |||
| NCI-H460 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human NCI-H460 cells after 48 hrs by MTT assay, IC50 = 29 μM. | 22304344 | ||
| B16 | Cytotoxicity assay | 48 hrs | Cytotoxicity against mouse B16 cells after 48 hrs by MTT assay, IC50 = 33 μM. | 22304344 | ||
| HepG2 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay, IC50 = 34 μM. | 22304344 | ||
| MCF7 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay, IC50 = 35 μM. | 22304344 | ||
| HeLa | Cytotoxicity assay | 48 hrs | Cytotoxicity against human HeLa cells after 48 hrs by MTT assay, IC50 = 43 μM. | 22304344 | ||
| SW1990 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human SW1990 cells after 48 hrs by MTT assay, IC50 = 45 μM. | 22304344 | ||
| SR | Cytotoxicity assay | 48 hrs | Cytotoxicity against human SR cells after 48 hrs by SRB assay, GI50 = 0.0238 μM. | 22305543 | ||
| NCI-H522 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human NCI-H522 cells after 48 hrs by SRB assay, GI50 = 7.28 μM. | 22305543 | ||
| WHCO1 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human WHCO1 cells after 48 hrs by MTT assay, IC50 = 7.9 μM. | 22381354 | ||
| HaCaT | Cytostatic activity assay | 72 hrs | Cytostatic activity against human HaCaT cells after 72 hrs by MTT assay, IC50 = 0.3 μM. | 22405290 | ||
| L1210 | Cytostatic activity assay | 2 days | Cytostatic activity against mouse L1210 cells after 2 days by coulter counter analysis, IC50 = 0.49 μM. | 22405290 | ||
| HeLa | Cytostatic activity assay | 3 days | Cytostatic activity against human HeLa cells after 3 days by coulter counter analysis, IC50 = 0.54 μM. | 22405290 | ||
| NCI-H460 | Cytostatic activity assay | 72 hrs | Cytostatic activity against human NCI-H460 cells after 72 hrs by MTT assay, IC50 = 3 μM. | 22405290 | ||
| HCT116 | Cytostatic activity assay | 72 hrs | Cytostatic activity against human HCT116 cells after 72 hrs by MTT assay, IC50 = 4 μM. | 22405290 | ||
| MCF7 | Cytostatic activity assay | 72 hrs | Cytostatic activity against human MCF7 cells after 72 hrs by MTT assay, IC50 = 15 μM. | 22405290 | ||
| CEM | Cytostatic activity assay | 3 days | Cytostatic activity against human CEM cells after 3 days by coulter counter analysis, IC50 = 18 μM. | 22405290 | ||
| MGC803 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human MGC803 cells after 48 hrs by MTT assay, IC50 = 3.42 μM. | 22405648 | ||
| Bcap37 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human Bcap37 cells after 48 hrs by MTT assay, IC50 = 5.33 μM. | 22405648 | ||
| SGC7901 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human SGC7901 cells after 48 hrs by MTT assay, IC50 = 7.11 μM. | 22405648 | ||
| MCF7 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human MCF7 cells after 72 hrs by SRB assay, IC50 = 3.5 μM. | 22409771 | ||
| HepG2 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human HepG2 cells after 72 hrs by SRB assay, IC50 = 5 μM. | 22409771 | ||
| HCT116 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human HCT116 cells after 72 hrs by SRB assay, IC50 = 6 μM. | 22409771 | ||
| FOCUS | Cytotoxicity assay | 72 hrs | Cytotoxicity against human FOCUS cells after 72 hrs by SRB assay, IC50 = 7.6 μM. | 22409771 | ||
| Mahlavu | Cytotoxicity assay | 72 hrs | Cytotoxicity against human Mahlavu cells after 72 hrs by SRB assay, IC50 = 10 μM. | 22409771 | ||
| HuH7 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human HuH7 cells after 72 hrs by SRB assay, IC50 = 30.7 μM. | 22409771 | ||
| K562 | Cytotoxicity assay | Cytotoxicity against human K562 cells, IC50 = 2.4 μM. | 22409967 | |||
| COLO205 | Cytotoxicity assay | Cytotoxicity against human COLO205 cells, IC50 = 4.17 μM. | 22409967 | |||
| KM12 | Cytotoxicity assay | Cytotoxicity against human KM12 cells, IC50 = 8.32 μM. | 22409967 | |||
| HCT116 | Cytotoxicity assay | Cytotoxicity against human HCT116 cells, IC50 = 8.51 μM. | 22409967 | |||
| HCT15 | Cytotoxicity assay | Cytotoxicity against human HCT15 cells, IC50 = 9.71 μM. | 22409967 | |||
| HT-29 | Cytotoxicity assay | Cytotoxicity against human HT-29 cells, IC50 = 10.2 μM. | 22409967 | |||
| HCC2998 | Cytotoxicity assay | Cytotoxicity against human HCC2998 cells, IC50 = 13.5 μM. | 22409967 | |||
| PC3 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human PC3 cells after 48 hrs by sulforhodamine B assay, IC50 = 2.1 μM. | 22424614 | ||
| MOLT4 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human MOLT4 cells after 48 hrs by sulforhodamine B assay, IC50 = 3.2 μM. | 22424614 | ||
| MCF7 | Antiproliferative assay | 144 hrs | Antiproliferative activity against human MCF7 cells assessed as growth inhibition after 144 hrs by crystal violet staining method, IC50 = 4.7 μM. | 22450132 | ||
| HT-29 | Antiproliferative assay | 144 hrs | Antiproliferative activity against human HT-29 cells assessed as growth inhibition after 144 hrs by crystal violet staining method, IC50 = 7.3 μM. | 22450132 | ||
| MDA-MB-231 | Antiproliferative assay | 144 hrs | Antiproliferative activity against human MDA-MB-231 cells assessed as growth inhibition after 144 hrs by crystal violet staining method, IC50 = 9.6 μM. | 22450132 | ||
| PC9 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human PC9 cells after 48 hrs by MTT assay, IC50 = 23.47 μM. | 22483608 | ||
| HCT116 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human HCT116 cells after 48 hrs by MTT assay, IC50 = 31.72 μM. | 22483608 | ||
| A549 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human A549 cells after 48 hrs by MTT assay, IC50 = 35.05 μM. | 22483608 | ||
| HepG2 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay, IC50 = 46.31 μM. | 22483608 | ||
| A375 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human A375 cells after 48 hrs by MTT assay, IC50 = 46.55 μM. | 22483608 | ||
| SKHEP1 | Growth inhibition assay | 48 hrs | Growth inhibition of human SKHEP1 cells after 48 hrs by SRB assay, GI50 = 6.3 μM. | 22512908 | ||
| NCI-H460 | Growth inhibition assay | 48 hrs | Growth inhibition of human NCI-H460 cells after 48 hrs by SRB assay, GI50 = 6.5 μM. | 22512908 | ||
| BxPC3 | Growth inhibition assay | 48 hrs | Growth inhibition of human BxPC3 cells after 48 hrs by SRB assay, GI50 = 8.2 μM. | 22512908 | ||
| MSC | Growth inhibition assay | 48 hrs | Growth inhibition of human MSC cells after 48 hrs by SRB assay, GI50 = 8.92 μM. | 22512908 | ||
| IGROV1 | Growth inhibition assay | 48 hrs | Growth inhibition of human IGROV1 cells after 48 hrs by SRB assay, GI50 = 9.1 μM. | 22512908 | ||
| DU145 | Growth inhibition assay | 48 hrs | Growth inhibition of human DU145 cells after 48 hrs by SRB assay, GI50 = 9.37 μM. | 22512908 | ||
| HUVEC | Growth inhibition assay | 48 hrs | Growth inhibition of HUVEC cells after 48 hrs by SRB assay, GI50 = 9.72 μM. | 22512908 | ||
| HCT116 | Growth inhibition assay | 48 hrs | Growth inhibition of human HCT116 cells after 48 hrs by SRB assay, GI50 = 9.9 μM. | 22512908 | ||
| MCF7 | Growth inhibition assay | 48 hrs | Growth inhibition of human MCF7 cells after 48 hrs by SRB assay, GI50 = 9.9 μM. | 22512908 | ||
| OVCAR5 | Growth inhibition assay | 48 hrs | Growth inhibition of human OVCAR5 cells after 48 hrs by SRB assay, GI50 = 20 μM. | 22512908 | ||
| HCT15 | Growth inhibition assay | 48 hrs | Growth inhibition of human HCT15 cells after 48 hrs by SRB assay, GI50 = 21 μM. | 22512908 | ||
| PC3 | Growth inhibition assay | 48 hrs | Growth inhibition of human PC3 cells after 48 hrs by SRB assay, GI50 = 21 μM. | 22512908 | ||
| MIAPaCa2 | Growth inhibition assay | 48 hrs | Growth inhibition of human MIAPaCa2 cells after 48 hrs by SRB assay, GI50 = 30 μM. | 22512908 | ||
| K562 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human K562 cells after 48 hrs by MTT assay, IC50 = 2.1 μM. | 22537362 | ||
| KB | Cytotoxicity assay | 48 hrs | Cytotoxicity against human KB cells after 48 hrs by MTT assay, IC50 = 6.8 μM. | 22537362 | ||
| KB/VCR | Cytotoxicity assay | 48 hrs | Cytotoxicity against human KB/VCR cells after 48 hrs by MTT assay, IC50 = 33.4 μM. | 22537362 | ||
| SW620 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human SW620 cells after 72 hrs by MTT assay, IC50 = 6.68 μM. | 22555152 | ||
| MIAPaCa2 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human MIAPaCa2 cells after 72 hrs by MTT assay, IC50 = 11.67 μM. | 22555152 | ||
| HeLa | Antiproliferative assay | 72 hrs | Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay, IC50 = 14.93 μM. | 22555152 | ||
| WI38 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human WI38 cells after 72 hrs by MTT assay, IC50 = 24.66 μM. | 22555152 | ||
| A549 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human A549 cells by after 48 hrs by MTT assay, IC50 = 5.64 μM. | 22579780 | ||
| SGC7901 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human SGC7901 cells by after 48 hrs by MTT assay, IC50 = 6.04 μM. | 22579780 | ||
| MDA-MB-231 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human MDA-MB-231 cells by after 48 hrs by MTT assay, IC50 = 13.65 μM. | 22579780 | ||
| QGY7701 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human QGY7701 cells by after 48 hrs by MTT assay, IC50 = 14.3 μM. | 22579780 | ||
| SW480 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human SW480 cells by after 48 hrs by MTT assay, IC50 = 15.71 μM. | 22579780 | ||
| HeLa | Cytotoxicity assay | 48 hrs | Cytotoxicity against human HeLa cells by after 48 hrs by MTT assay, IC50 = 16.32 μM. | 22579780 | ||
| L02 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human L02 cells by after 48 hrs by MTT assay, IC50 = 46.57 μM. | 22579780 | ||
| SH-SY5Y | Cytotoxicity assay | 72 hrs | Cytotoxicity against human SH-SY5Y cells after 72 hrs by MTT assay, IC50 = 1.09 μM. | 22687745 | ||
| L929 | Cytotoxicity assay | 72 hrs | Cytotoxicity against mouse L929 cells after 72 hrs by MTT assay, IC50 = 1.38 μM. | 22687745 | ||
| A549 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human A549 cells after 72 hrs by MTT assay, IC50 = 8.83 μM. | 22687745 | ||
| DU145 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human DU145 cells after 72 hrs by MTT assay, IC50 = 12.32 μM. | 22687745 | ||
| SGC7901 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human SGC7901 cells after 72 hrs by MTT assay, IC50 = 14.49 μM. | 22687745 | ||
| HeLa | Cytotoxicity assay | 72 hrs | Cytotoxicity against human HeLa cells after 72 hrs by MTT assay, IC50 = 15.99 μM. | 22687745 | ||
| HepG2 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay, IC50 = 32.22 μM. | 22687745 | ||
| NCI-H460 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human NCI-H460 cells after 72 hrs by MTT assay, IC50 = 2.4 μM. | 22727445 | ||
| BGC823 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human BGC823 cells after 72 hrs by MTT assay, IC50 = 4.5 μM. | 22727445 | ||
| HepG2 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay, IC50 = 4.8 μM. | 22727445 | ||
| SGC7901 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human SGC7901 cells after 72 hrs by MTT assay, IC50 = 6.3 μM. | 22727445 | ||
| MCF7 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay, IC50 = 12.5 μM. | 22727445 | ||
| KB | Cytotoxicity assay | 72 hrs | Cytotoxicity against human KB cells after 72 hrs by MTT assay, IC50 = 8.28 μM. | 22749192 | ||
| MCF7 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay, IC50 = 14.2 μM. | 22749192 | ||
| CNE2 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human CNE2 cells after 72 hrs by MTT assay, IC50 = 15.1 μM. | 22749192 | ||
| GLC82 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human GLC82 cells after 72 hrs by MTT assay, IC50 = 17.4 μM. | 22749192 | ||
| MGC803 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human MGC803 cells after 72 hrs by MTT assay, IC50 = 18.5 μM. | 22749192 | ||
| MCF7 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human MCF7 cells after 72 hrs by crystal violet staining method, IC50 = 4.7 μM. | 22765897 | ||
| HT-29 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human HT-29 cells after 72 hrs by crystal violet staining method, IC50 = 7.3 μM. | 22765897 | ||
| MDA-MB-231 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by crystal violet staining method, IC50 = 9.6 μM. | 22765897 | ||
| HT1080 | Cytotoxicity assay | Cytotoxicity against human HT1080 cells by MTT assay, IC50 = 3.06 μM. | 22801644 | |||
| A375-S2 | Cytotoxicity assay | Cytotoxicity against human A375-S2 cells by MTT assay, IC50 = 9.92 μM. | 22801644 | |||
| HeLa | Cytotoxicity assay | Cytotoxicity against human HeLa cells by MTT assay, IC50 = 10.36 μM. | 22801644 | |||
| HepG2 | Cytotoxicity assay | Cytotoxicity against human HepG2 cells by MTT assay, IC50 = 10.45 μM. | 22801644 | |||
| BGC823 | Cytotoxicity assay | Cytotoxicity against human BGC823 cells by MTT assay, IC50 = 15.65 μM. | 22801644 | |||
| Hep2 | Cytotoxicity assay | Cytotoxicity against human Hep2 cells by MTT assay, IC50 = 24.58 μM. | 22801644 | |||
| MCF7 | Cytotoxicity assay | Cytotoxicity against human MCF7 cells by MTT assay, IC50 = 24.58 μM. | 22801644 | |||
| A549 | Cytotoxicity assay | Cytotoxicity against human A549 cells by MTT assay, IC50 = 31.52 μM. | 22801644 | |||
| MDA231 | Cytotoxicity assay | Cytotoxicity against human MDA231 cells by MTT assay, IC50 = 31.57 μM. | 22801644 | |||
| PC3 | Cytotoxicity assay | Cytotoxicity against human PC3 cells by MTT assay, IC50 = 35.75 μM. | 22801644 | |||
| PC3M | Cytotoxicity assay | 48 hrs | Cytotoxicity against human PC3M cells after 48 hrs by MTT assay, IC50 = 22.63 μM. | 22809558 | ||
| A549 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human A549 cells after 48 hrs by MTT assay, IC50 = 35.41 μM. | 22809558 | ||
| MKN45 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human MKN45 cells after 48 hrs by MTT assay, IC50 = 41.73 μM. | 22809558 | ||
| HepG2 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay, IC50 = 46.83 μM. | 22809558 | ||
| LoVo | Antiproliferative assay | 48 hrs | Antiproliferative activity against human LoVo cells after 48 hrs by MTT assay, IC50 = 3.3 μM. | 22840493 | ||
| A549 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human A549 cells after 48 hrs by MTT assay, IC50 = 12.8 μM. | 22840493 | ||
| MCF7 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay, IC50 = 16.2 μM. | 22840493 | ||
| IOSE-144 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human IOSE-144 cells after 48 hrs by MTT assay, IC50 = 25.6 μM. | 22840493 | ||
| CAMA1 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human CAMA1 cells incubated for 72 hrs by SRB assay, IC50 = 1.28 μM. | 22867707 | ||
| MCF7 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human MCF7 cells incubated for 72 hrs by SRB assay, IC50 = 3.5 μM. | 22867707 | ||
| HepG2 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human HepG2 cells incubated for 72 hrs by SRB assay, IC50 = 5.7 μM. | 22867707 | ||
| FOCUS | Cytotoxicity assay | 72 hrs | Cytotoxicity against human FOCUS cells incubated for 72 hrs by SRB assay, IC50 = 7.69 μM. | 22867707 | ||
| T47D | Cytotoxicity assay | 72 hrs | Cytotoxicity against human T47D cells incubated for 72 hrs by SRB assay, IC50 = 8.91 μM. | 22867707 | ||
| MV | Cytotoxicity assay | 72 hrs | Cytotoxicity against human MV cells incubated for 72 hrs by SRB assay, IC50 = 9.97 μM. | 22867707 | ||
| HCT116 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human HCT116 cells incubated for 72 hrs by SRB assay, IC50 = 18.7 μM. | 22867707 | ||
| MFE296 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human MFE296 cells incubated for 72 hrs by SRB assay, IC50 = 30.68 μM. | 22867707 | ||
| HuH7 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human HuH7 cells incubated for 72 hrs by SRB assay, IC50 = 30.7 μM. | 22867707 | ||
| BT20 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human BT20 cells incubated for 72 hrs by SRB assay, IC50 = 47.3 μM. | 22867707 | ||
| COLO320 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human COLO320 cells assessed as cell viability after 72 hrs by WST-1 assay, IC50 = 12.5 μM. | 22955095 | ||
| MCF7 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human MCF7 cells after 72 hrs by crystal violet staining, IC50 = 4.7 μM. | 22959205 | ||
| HT-29 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human HT-29 cells after 72 hrs by crystal violet staining, IC50 = 7.3 μM. | 22959205 | ||
| MDA-MB-231 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human MDA-MB-231 cells after 72 hrs by crystal violet staining, IC50 = 9.6 μM. | 22959205 | ||
| HL60 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human HL60 cells after 72 hrs by MTT assay, IC50 = 0.06 μM. | 22959518 | ||
| HeLa | Cytotoxicity assay | 72 hrs | Cytotoxicity against human HeLa cells after 72 hrs by MTT assay, IC50 = 0.28 μM. | 22959518 | ||
| U937 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human U937 cells after 72 hrs by MTT assay, IC50 = 1.07 μM. | 22959518 | ||
| colon cancer | Antiproliferative assay | 48 hrs | Antiproliferative activity against human colon cancer cells after 48 hrs by cell counting analysis, GI50 = 8.4 μM. | 22995621 | ||
| leukemia | Antiproliferative assay | 48 hrs | Antiproliferative activity against human leukemia cells after 48 hrs by cell counting analysis, GI50 = 15.1 μM. | 22995621 | ||
| prostate cancer | Antiproliferative assay | 48 hrs | Antiproliferative activity against human prostate cancer cells after 48 hrs by cell counting analysis, GI50 = 22.7 μM. | 22995621 | ||
| renal cancer | Antiproliferative assay | 48 hrs | Antiproliferative activity against human renal cancer cells after 48 hrs by cell counting analysis, GI50 = 45.6 μM. | 22995621 | ||
| HeLa | Cytotoxicity assay | 48 hrs | Cytotoxicity against human HeLa cells after 48 hrs by MTT assay, IC50 = 9.5 μM. | 23002924 | ||
| MNK45 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human MNK45 cells after 48 hrs by MTT assay, IC50 = 12 μM. | 23002924 | ||
| HepG2 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human HepG2 cells after 48 hrs by MTT method, IC50 = 1.3 μM. | 23018096 | ||
| BGC823 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human BGC823 cells after 48 hrs by MTT method, IC50 = 1.52 μM. | 23018096 | ||
| SW1116 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human SW1116 cells after 48 hrs by MTT method, IC50 = 2.41 μM. | 23018096 | ||
| HeLa | Antiproliferative assay | 48 hrs | Antiproliferative activity against human HeLa cells after 48 hrs by MTT method, IC50 = 3.25 μM. | 23018096 | ||
| A549 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human A549 cells assessed cell viability after 48 hrs by SRB assay, IC50 = 4.21 μM. | 23044370 | ||
| HT1080 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human HT1080 cells after 48 hrs by MTT assay, IC50 = 15.2 μM. | 23067549 | ||
| HCT116 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human HCT116 cells after 48 hrs by MTT assay, IC50 = 36.4 μM. | 23067549 | ||
| 2008 | Growth inhibition assay | Growth inhibition of human 2008 cells by crystal violet assay, IC50 = 4.2 μM. | 23075414 | |||
| Vero | Growth inhibition assay | Growth inhibition of african green monkey Vero cells by crystal violet assay, IC50 = 4.5 μM. | 23075414 | |||
| A2780 | Growth inhibition assay | Growth inhibition of human A2780 cells by crystal violet assay, IC50 = 5.1 μM. | 23075414 | |||
| C13 | Growth inhibition assay | Growth inhibition of cDDP-resistant human C13 cells by crystal violet assay, IC50 = 8.5 μM. | 23075414 | |||
| A2780/CP70 | Growth inhibition assay | Growth inhibition of cDDP-resistant human A2780/CP70 cells by crystal violet assay, IC50 = 12.3 μM. | 23075414 | |||
| MSC | Growth inhibition assay | 48 hrs | Growth inhibition of human MSC cells after 48 hrs by SRB assay, GI50 = 0.001 μM. | 23094992 | ||
| MSC | Growth inhibition assay | 48 hrs | Growth inhibition of human MSC cells after 48 hrs by SRB assay, TGI = 0.001 μM. | 23094992 | ||
| BxPC3 | Growth inhibition assay | 48 hrs | Growth inhibition of human BxPC3 cells after 48 hrs by SRB assay, GI50 = 0.0029 μM. | 23094992 | ||
| HUVEC | Growth inhibition assay | 48 hrs | Growth inhibition of human HUVEC cells after 48 hrs by SRB assay, GI50 = 0.0036 μM. | 23094992 | ||
| SKHEP1 | Growth inhibition assay | 48 hrs | Growth inhibition of human SKHEP1 cells after 48 hrs by SRB assay, GI50 = 0.0076 μM. | 23094992 | ||
| IGROV1 | Growth inhibition assay | 48 hrs | Growth inhibition of human IGROV1 cells after 48 hrs by SRB assay, GI50 = 0.00812 μM. | 23094992 | ||
| BxPC3 | Growth inhibition assay | 48 hrs | Growth inhibition of human BxPC3 cells after 48 hrs by SRB assay, TGI = 0.0084 μM. | 23094992 | ||
| HCT116 | Growth inhibition assay | 48 hrs | Growth inhibition of human HCT116 cells after 48 hrs by SRB assay, GI50 = 0.0088 μM. | 23094992 | ||
| PC3 | Growth inhibition assay | 48 hrs | Growth inhibition of human PC3 cells after 48 hrs by SRB assay, GI50 = 0.01045 μM. | 23094992 | ||
| MCF7 | Growth inhibition assay | 48 hrs | Growth inhibition of human MCF7 cells after 48 hrs by SRB assay, GI50 = 0.0145 μM. | 23094992 | ||
| DU145 | Growth inhibition assay | 48 hrs | Growth inhibition of human DU145 cells after 48 hrs by SRB assay, GI50 = 0.02 μM. | 23094992 | ||
| HCT15 | Growth inhibition assay | 48 hrs | Growth inhibition of human HCT15 cells after 48 hrs by SRB assay, GI50 = 0.0211 μM. | 23094992 | ||
| OVCAR5 | Growth inhibition assay | 48 hrs | Growth inhibition of human OVCAR5 cells after 48 hrs by SRB assay, GI50 = 0.0264 μM. | 23094992 | ||
| MIAPaCa2 | Growth inhibition assay | 48 hrs | Growth inhibition of human MIAPaCa2 cells after 48 hrs by SRB assay, GI50 = 0.0306 μM. | 23094992 | ||
| NHDF | Growth inhibition assay | 48 hrs | Growth inhibition of human NHDF cells after 48 hrs by SRB assay, GI50 = 0.06202 μM. | 23094992 | ||
| U251 | Growth inhibition assay | 48 hrs | Growth inhibition of human U251 cells after 48 hrs by SRB assay, GI50 = 0.0696 μM. | 23094992 | ||
| NHDF | Growth inhibition assay | 48 hrs | Growth inhibition of human NHDF cells after 48 hrs by SRB assay, TGI = 0.1 μM. | 23094992 | ||
| MIAPaCa2 | Growth inhibition assay | 48 hrs | Growth inhibition of human MIAPaCa2 cells after 48 hrs by SRB assay, TGI = 0.1 μM. | 23094992 | ||
| HUVEC | Growth inhibition assay | 48 hrs | Growth inhibition of human HUVEC cells after 48 hrs by SRB assay, TGI = 0.1 μM. | 23094992 | ||
| OVCAR5 | Growth inhibition assay | 48 hrs | Growth inhibition of human OVCAR5 cells after 48 hrs by SRB assay, TGI = 0.1 μM. | 23094992 | ||
| HL-60(TB) | Growth inhibition assay | 48 hrs | Growth inhibition of human HL-60(TB) cells after 48 hrs by SRB assay, GI50 = 0.1 μM. | 23094992 | ||
| HL-60(TB) | Growth inhibition assay | 48 hrs | Growth inhibition of human HL-60(TB) cells after 48 hrs by SRB assay, TGI = 0.1 μM. | 23094992 | ||
| U251 | Growth inhibition assay | 48 hrs | Growth inhibition of human U251 cells after 48 hrs by SRB assay, TGI = 0.1 μM. | 23094992 | ||
| DU145 | Growth inhibition assay | 48 hrs | Growth inhibition of human DU145 cells after 48 hrs by SRB assay, TGI = 0.1 μM. | 23094992 | ||
| SKHEP1 | Growth inhibition assay | 48 hrs | Growth inhibition of human SKHEP1 cells after 48 hrs by SRB assay, TGI = 0.1 μM. | 23094992 | ||
| MCF7 | Growth inhibition assay | 48 hrs | Growth inhibition of human MCF7 cells after 48 hrs by SRB assay, TGI = 0.1 μM. | 23094992 | ||
| HCT15 | Growth inhibition assay | 48 hrs | Growth inhibition of human HCT15 cells after 48 hrs by SRB assay, TGI = 0.1 μM. | 23094992 | ||
| IGROV1 | Growth inhibition assay | 48 hrs | Growth inhibition of human IGROV1 cells after 48 hrs by SRB assay, TGI = 0.1 μM. | 23094992 | ||
| PC3 | Growth inhibition assay | 48 hrs | Growth inhibition of human PC3 cells after 48 hrs by SRB assay, TGI = 0.1 μM. | 23094992 | ||
| HCT116 | Growth inhibition assay | 48 hrs | Growth inhibition of human HCT116 cells after 48 hrs by SRB assay, TGI = 0.1 μM. | 23094992 | ||
| A549 | Cytotoxicity assay | Cytotoxicity against human A549 cells by MTT method, IC50 = 1.54 μM. | 23164710 | |||
| BGC823 | Cytotoxicity assay | Cytotoxicity against human BGC823 cells by MTT method, IC50 = 3.84 μM. | 23164710 | |||
| Bel7042 | Cytotoxicity assay | Cytotoxicity against human Bel7042 cells by MTT method, IC50 = 3.85 μM. | 23164710 | |||
| HCT8 | Cytotoxicity assay | Cytotoxicity against human HCT8 cells by MTT method, IC50 = 5.38 μM. | 23164710 | |||
| A2780 | Cytotoxicity assay | Cytotoxicity against human A2780 cells by MTT method, IC50 = 5.4 μM. | 23164710 | |||
| NIH-H460 | Cytotoxicity assay | Cytotoxicity against human NIH-H460 cells by MTT method, IC50 = 7.12 μM. | 23164710 | |||
| HepG2 | Cytotoxicity assay | 24 hrs | Cytotoxicity against human HepG2 cells after 24 hrs by MTT assay, IC50 = 29.87 μM. | 23202484 | ||
| PA1 | Cytotoxicity assay | 24 hrs | Cytotoxicity against human PA1 cells after 24 hrs by MTT assay, IC50 = 39.5 μM. | 23202484 | ||
| HCT15 | Cytotoxicity assay | 24 hrs | Cytotoxicity against human HCT15 cells after 24 hrs by MTT assay, IC50 = 45.01 μM. | 23202484 | ||
| MCF7 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay, IC50 = 17.2 μM. | 23279864 | ||
| HepG2 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay, IC50 = 21.9 μM. | 23279864 | ||
| SGC7901 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human SGC7901 cells after 72 hrs by MTT assay, IC50 = 28.5 μM. | 23279864 | ||
| HCT116 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human HCT116 cells assessed as inhibition cell proliferation after 48 hrs by Sulforhodamine B assay, IC50 = 3.56 μM. | 23305919 | ||
| B16F10 | Anticancer assay | 48 hrs | Anticancer activity against mouse B16F10 cells assessed as cell survival measured after 48 hrs by MTT assay, IC50 = 21.41 μM. | 23312949 | ||
| SGC7901 | Anticancer assay | 48 hrs | Anticancer activity against human SGC7901 cells assessed as cell survival measured after 48 hrs by MTT assay, IC50 = 46.35 μM. | 23312949 | ||
| HeLa | Antitumor assay | 48 hrs | Antitumor activity against human HeLa cells assessed as growth inhibition measured after 48 hrs by MTT assay, IC50 = 14.78 μM. | 23313635 | ||
| A549 | Growth inhibition assay | 48 hrs | Growth inhibition of human A549 cells after 48 hrs by MTT assay, IC50 = 5.64 μM. | 23353737 | ||
| QGY7701 | Growth inhibition assay | 48 hrs | Growth inhibition of human QGY7701 cells after 48 hrs by MTT assay, IC50 = 14.3 μM. | 23353737 | ||
| HuH7 | Growth inhibition assay | 48 hrs | Growth inhibition of human HuH7 cells after 48 hrs by MTT assay, IC50 = 15.85 μM. | 23353737 | ||
| HeLa | Growth inhibition assay | 48 hrs | Growth inhibition of human HeLa cells after 48 hrs by MTT assay, IC50 = 16.32 μM. | 23353737 | ||
| L02 | Growth inhibition assay | 48 hrs | Growth inhibition of human L02 cells after 48 hrs by MTT assay, IC50 = 46.57 μM. | 23353737 | ||
| EC109 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human EC109 cells assessed as growth inhibition after 72 hrs by MTT assay, IC50 = 3.34 μM. | 23353743 | ||
| MGC803 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human MGC803 cells assessed as growth inhibition after 72 hrs by MTT assay, IC50 = 7.01 μM. | 23353743 | ||
| MCF7 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human MCF7 cells assessed as growth inhibition after 72 hrs by MTT assay, IC50 = 7.54 μM. | 23353743 | ||
| PC3 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human PC3 cells assessed as growth inhibition after 72 hrs by MTT assay, IC50 = 27.07 μM. | 23353743 | ||
| colon cancer | Cytotoxicity assay | 48 hrs | Cytotoxicity against human colon cancer cells after 48 hrs by sulphorhodamine B assay, GI50 = 8.4 μM. | 23474899 | ||
| leukemia | Cytotoxicity assay | 48 hrs | Cytotoxicity against human leukemia cells after 48 hrs by sulphorhodamine B assay, GI50 = 15.1 μM. | 23474899 | ||
| prostate cancer | Cytotoxicity assay | 48 hrs | Cytotoxicity against human prostate cancer cells after 48 hrs by sulphorhodamine B assay, GI50 = 22.7 μM. | 23474899 | ||
| renal cancer | Cytotoxicity assay | 48 hrs | Cytotoxicity against human renal cancer cells after 48 hrs by sulphorhodamine B assay, GI50 = 45.6 μM. | 23474899 | ||
| MCF7 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay, IC50 = 16.7 μM. | 23490159 | ||
| HepG2 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay, IC50 = 22.8 μM. | 23490159 | ||
| SGC7901 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human SGC7901 cells after 48 hrs by MTT assay, IC50 = 28.9 μM. | 23490159 | ||
| THP1 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human THP1 cells after 48 hrs by sulforhodamine B assay, IC50 = 1 μM. | 23501113 | ||
| PC3 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human PC3 cells after 48 hrs by sulforhodamine B assay, IC50 = 2.2 μM. | 23501113 | ||
| Hep2 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human Hep2 cells after 48 hrs by sulforhodamine B assay, IC50 = 4.5 μM. | 23501113 | ||
| A549 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human A549 cells after 48 hrs by sulforhodamine B assay, IC50 = 4.9 μM. | 23501113 | ||
| K562 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human K562 cells after 72 hrs by MTT assay, IC50 = 28 μM. | 23535322 | ||
| CEM | Cytotoxicity assay | 72 hrs | Cytotoxicity against human CEM cells after 72 hrs by MTT assay, IC50 = 32 μM. | 23535322 | ||
| A375-S2 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human A375-S2 cells after 48 hrs by MTT assay, IC50 = 6.67 μM. | 23558238 | ||
| HeLa | Cytotoxicity assay | 48 hrs | Cytotoxicity against human HeLa cells after 48 hrs by MTT assay, IC50 = 7.34 μM. | 23558238 | ||
| HL60 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human HL60 cells after 48 hrs by MTT assay, IC50 = 10.05 μM. | 23558238 | ||
| MCF7 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay, IC50 = 11.5 μM. | 23558238 | ||
| K562 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human K562 cells after 48 hrs by MTT assay, IC50 = 23.55 μM. | 23558238 | ||
| U937 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human U937 cells after 48 hrs by MTT assay, IC50 = 23.93 μM. | 23558238 | ||
| HCT116 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human HCT116 cells after 48 hrs by MTT assay, IC50 = 27.76 μM. | 23558238 | ||
| HT1080 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human HT1080 cells after 48 hrs by MTT assay, IC50 = 35.62 μM. | 23558238 | ||
| HepG2 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay, IC50 = 40.34 μM. | 23558238 | ||
| A549 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human A549 cells after 48 hrs by MTT assay, IC50 = 44.05 μM. | 23558238 | ||
| EC9706 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human EC9706 cells after 72 hrs by MTT assay, IC50 = 0.32 μM. | 23644193 | ||
| MGC803 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human MGC803 cells after 72 hrs by MTT assay, IC50 = 7.14 μM. | 23644193 | ||
| MCF7 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay, IC50 = 7.33 μM. | 23644193 | ||
| SMMC7721 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human SMMC7721 cells after 72 hrs by MTT assay, IC50 = 26.71 μM. | 23644193 | ||
| HCT116 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human HCT116 cells after 48 hrs by sulforhodamine B assay, IC50 = 4.52 μM. | 23644215 | ||
| HT-29 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human HT-29 cells after 48 hrs by sulforhodamine B assay, IC50 = 6.35 μM. | 23644215 | ||
| A549 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human A549 cells after 72 hrs by MTT assay, IC50 = 3.52 μM. | 23665106 | ||
| HCT116 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay, IC50 = 5.53 μM. | 23665106 | ||
| HT-29 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human HT-29 cells after 72 hrs by MTT assay, IC50 = 24.5 μM. | 23665106 | ||
| MCF7 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay, IC50 = 32.18 μM. | 23665106 | ||
| HeLa | Antiproliferative assay | 72 hrs | Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay, IC50 = 43.71 μM. | 23665106 | ||
| colon cancer | Cytotoxicity assay | 48 hrs | Cytotoxicity against human colon cancer cells after 48 hrs by coulter counter analysis, GI50 = 8.4 μM. | 23683592 | ||
| leukemia | Cytotoxicity assay | 48 hrs | Cytotoxicity against human leukemia cells after 48 hrs by coulter counter analysis, GI50 = 15.1 μM. | 23683592 | ||
| prostate cancer | Cytotoxicity assay | 48 hrs | Cytotoxicity against human prostate cancer cells after 48 hrs by coulter counter analysis, GI50 = 22.7 μM. | 23683592 | ||
| renal cancer | Cytotoxicity assay | 48 hrs | Cytotoxicity against human renal cancer cells after 48 hrs by coulter counter analysis, GI50 = 45.6 μM. | 23683592 | ||
| SH-SY5Y | Cytotoxicity assay | 72 hrs | Cytotoxicity against human SH-SY5Y cells after 72 hrs by MTT assay, IC50 = 0.97 μM. | 23685571 | ||
| HCT116 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human HCT116 cells after 72 hrs by MTT assay, IC50 = 3.24 μM. | 23685571 | ||
| A549 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human A549 cells after 72 hrs by MTT assay, IC50 = 8.71 μM. | 23685571 | ||
| Vero | Cytotoxicity assay | 72 hrs | Cytotoxicity against African green monkey Vero cells after 72 hrs by MTT assay, IC50 = 9.71 μM. | 23685571 | ||
| MCF7 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay, IC50 = 10.14 μM. | 23685571 | ||
| HepG2 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay, IC50 = 24.96 μM. | 23685571 | ||
| PC3 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human PC3 cells expressing SKP2 after 72 hrs by MTT assay, IC50 = 27.07 μM. | 23735281 | ||
| PC3 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human PC3 cells expressing PCDNA after 72 hrs by MTT assay, IC50 = 31.44 μM. | 23735281 | ||
| COLO320DM | Cytotoxicity assay | 48 hrs | Cytotoxicity against human COLO320DM cells after 48 hrs by MTT assay, IC50 = 2 μM. | 23792352 | ||
| HeLa | Cytotoxicity assay | 72 hrs | Cytotoxicity against human HeLa cells after 72 hrs by MTT assay, IC50 = 3.4 μM. | 23792763 | ||
| MCF7 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay, IC50 = 3.6 μM. | 23792763 | ||
| SW480 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human SW480 cells after 72 hrs by MTT assay, IC50 = 8.1 μM. | 23792763 | ||
| MDA-MB-435S | Cytotoxicity assay | 72 hrs | Cytotoxicity against human MDA-MB-435S cells after 72 hrs by MTT assay, IC50 = 14.5 μM. | 23792763 | ||
| LM7 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human LM7 cells after 72 hrs by MTT assay, IC50 = 18.6 μM. | 23792763 | ||
| MGC803 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human MGC803 cells after 72 hrs by MTT assay, IC50 = 6.92 μM. | 23792764 | ||
| MCF7 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay, IC50 = 7.54 μM. | 23792764 | ||
| SMMC7721 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human SMMC7721 cells after 72 hrs by MTT assay, IC50 = 9.78 μM. | 23792764 | ||
| EC109 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human EC109 cells after 72 hrs by MTT assay, IC50 = 10.61 μM. | 23792764 | ||
| PC3 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human PC3 cells after 72 hrs by MTT assay, IC50 = 24.76 μM. | 23792764 | ||
| MCF7 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay, IC50 = 5 μM. | 23800391 | ||
| Vero | Antiproliferative assay | 48 hrs | Antiproliferative activity against african green monkey Vero cells after 48 hrs by MTT assay, IC50 = 8 μM. | 23800391 | ||
| WI38 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human WI38 cells after 48 hrs by MTT assay, IC50 = 10 μM. | 23800391 | ||
| HepG2 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay, IC50 = 10 μM. | 23800391 | ||
| HL60 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human HL60 cells after 48 hrs by MTT assay, IC50 = 22.3 μM. | 23867385 | ||
| H460 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human H460 cells after 48 hrs by MTT assay, IC50 = 26.7 μM. | 23867385 | ||
| KB | Cytotoxicity assay | 72 hrs | Cytotoxicity against human KB cells after 72 hrs by SRB assay, IC50 = 4.84 μM. | 23867603 | ||
| HeLa | Cytotoxicity assay | 72 hrs | Cytotoxicity against human HeLa cells after 72 hrs by SRB assay, IC50 = 6.23 μM. | 23867603 | ||
| MCF7 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human MCF7 cells after 72 hrs by SRB assay, IC50 = 6.53 μM. | 23867603 | ||
| OVCAR3 | Growth inhibition assay | 48 hrs | Growth inhibition of human OVCAR3 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.01 μM. | 23887055 | ||
| SR | Growth inhibition assay | 48 hrs | Growth inhibition of human SR cells after 48 hrs by sulforhodamine B assay, GI50 = 0.02 μM. | 23887055 | ||
| RPMI8226 | Growth inhibition assay | 48 hrs | Growth inhibition of human RPMI8226 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.04 μM. | 23887055 | ||
| MALME-3M | Growth inhibition assay | 48 hrs | Growth inhibition of human MALME-3M cells after 48 hrs by sulforhodamine B assay, GI50 = 0.05 μM. | 23887055 | ||
| HCC2998 | Growth inhibition assay | 48 hrs | Growth inhibition of human HCC2998 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.05 μM. | 23887055 | ||
| NCI-H460 | Growth inhibition assay | 48 hrs | Growth inhibition of human NCI-H460 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.05 μM. | 23887055 | ||
| SF539 | Growth inhibition assay | 48 hrs | Growth inhibition of human SF539 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.06 μM. | 23887055 | ||
| MCF7 | Growth inhibition assay | 48 hrs | Growth inhibition of human MCF7 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.07 μM. | 23887055 | ||
| CAKI-1 | Growth inhibition assay | 48 hrs | Growth inhibition of human CAKI-1 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.07 μM. | 23887055 | ||
| MDA-MB-435 | Growth inhibition assay | 48 hrs | Growth inhibition of human MDA-MB-435 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.07 μM. | 23887055 | ||
| HCT15 | Growth inhibition assay | 48 hrs | Growth inhibition of human HCT15 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.11 μM. | 23887055 | ||
| COLO205 | Growth inhibition assay | 48 hrs | Growth inhibition of human COLO205 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.15 μM. | 23887055 | ||
| HT-29 | Growth inhibition assay | 48 hrs | Growth inhibition of human HT-29 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.17 μM. | 23887055 | ||
| A549/ATCC | Growth inhibition assay | 48 hrs | Growth inhibition of human A549/ATCC cells after 48 hrs by sulforhodamine B assay, GI50 = 0.18 μM. | 23887055 | ||
| KM12 | Growth inhibition assay | 48 hrs | Growth inhibition of human KM12 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.21 μM. | 23887055 | ||
| HCT116 | Growth inhibition assay | 48 hrs | Growth inhibition of human HCT116 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.22 μM. | 23887055 | ||
| SF295 | Growth inhibition assay | 48 hrs | Growth inhibition of human SF295 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.22 μM. | 23887055 | ||
| LOXIMVI | Growth inhibition assay | 48 hrs | Growth inhibition of human LOXIMVI cells after 48 hrs by sulforhodamine B assay, GI50 = 0.24 μM. | 23887055 | ||
| ACHN | Growth inhibition assay | 48 hrs | Growth inhibition of human ACHN cells after 48 hrs by sulforhodamine B assay, GI50 = 0.29 μM. | 23887055 | ||
| NCI-ADR-RES | Growth inhibition assay | 48 hrs | Growth inhibition of human NCI-ADR-RES cells after 48 hrs by sulforhodamine B assay, GI50 = 0.31 μM. | 23887055 | ||
| NCI-H23 | Growth inhibition assay | 48 hrs | Growth inhibition of human NCI-H23 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.33 μM. | 23887055 | ||
| A498 | Growth inhibition assay | 48 hrs | Growth inhibition of human A498 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.35 μM. | 23887055 | ||
| MOLT4 | Growth inhibition assay | 48 hrs | Growth inhibition of human MOLT4 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.35 μM. | 23887055 | ||
| DU145 | Growth inhibition assay | 48 hrs | Growth inhibition of human DU145 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.36 μM. | 23887055 | ||
| HOP62 | Growth inhibition assay | 48 hrs | Growth inhibition of human HOP62 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.39 μM. | 23887055 | ||
| SK-MEL-5 | Growth inhibition assay | 48 hrs | Growth inhibition of human SK-MEL-5 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.46 μM. | 23887055 | ||
| SN12C | Growth inhibition assay | 48 hrs | Growth inhibition of human SN12C cells after 48 hrs by sulforhodamine B assay, GI50 = 0.49 μM. | 23887055 | ||
| UACC62 | Growth inhibition assay | 48 hrs | Growth inhibition of human UACC62 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.52 μM. | 23887055 | ||
| 786-0 | Growth inhibition assay | 48 hrs | Growth inhibition of human 786-0 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.72 μM. | 23887055 | ||
| U251 | Growth inhibition assay | 48 hrs | Growth inhibition of human U251 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.9 μM. | 23887055 | ||
| SW620 | Growth inhibition assay | 48 hrs | Growth inhibition of human SW620 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.92 μM. | 23887055 | ||
| M14 | Growth inhibition assay | 48 hrs | Growth inhibition of human M14 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.98 μM. | 23887055 | ||
| SK-MEL-28 | Growth inhibition assay | 48 hrs | Growth inhibition of human SK-MEL-28 cells after 48 hrs by sulforhodamine B assay, GI50 = 1.03 μM. | 23887055 | ||
| TK10 | Growth inhibition assay | 48 hrs | Growth inhibition of human TK10 cells after 48 hrs by sulforhodamine B assay, GI50 = 1.12 μM. | 23887055 | ||
| IGROV1 | Growth inhibition assay | 48 hrs | Growth inhibition of human IGROV1 cells after 48 hrs by sulforhodamine B assay, GI50 = 1.22 μM. | 23887055 | ||
| UO31 | Growth inhibition assay | 48 hrs | Growth inhibition of human UO31 cells after 48 hrs by sulforhodamine B assay, GI50 = 1.42 μM. | 23887055 | ||
| SF268 | Growth inhibition assay | 48 hrs | Growth inhibition of human SF268 cells after 48 hrs by sulforhodamine B assay, GI50 = 1.62 μM. | 23887055 | ||
| OVCAR8 | Growth inhibition assay | 48 hrs | Growth inhibition of human OVCAR8 cells after 48 hrs by sulforhodamine B assay, GI50 = 1.74 μM. | 23887055 | ||
| HL-60(TB) | Growth inhibition assay | 48 hrs | Growth inhibition of human HL-60(TB) cells after 48 hrs by sulforhodamine B assay, GI50 = 2.3 μM. | 23887055 | ||
| PC3 | Growth inhibition assay | 48 hrs | Growth inhibition of human PC3 cells after 48 hrs by sulforhodamine B assay, GI50 = 2.36 μM. | 23887055 | ||
| RXF393 | Growth inhibition assay | 48 hrs | Growth inhibition of human RXF393 cells after 48 hrs by sulforhodamine B assay, GI50 = 2.61 μM. | 23887055 | ||
| UACC257 | Growth inhibition assay | 48 hrs | Growth inhibition of human UACC257 cells after 48 hrs by sulforhodamine B assay, GI50 = 3.55 μM. | 23887055 | ||
| K562 | Growth inhibition assay | 48 hrs | Growth inhibition of human K562 cells after 48 hrs by sulforhodamine B assay, GI50 = 3.58 μM. | 23887055 | ||
| SNB19 | Growth inhibition assay | 48 hrs | Growth inhibition of human SNB19 cells after 48 hrs by sulforhodamine B assay, GI50 = 3.81 μM. | 23887055 | ||
| OVCAR4 | Growth inhibition assay | 48 hrs | Growth inhibition of human OVCAR4 cells after 48 hrs by sulforhodamine B assay, GI50 = 4.43 μM. | 23887055 | ||
| MDA-MB-231 | Growth inhibition assay | 48 hrs | Growth inhibition of human MDA-MB-231 cells after 48 hrs by sulforhodamine B assay, GI50 = 6.6 μM. | 23887055 | ||
| NCI-H522 | Growth inhibition assay | 48 hrs | Growth inhibition of human NCI-H522 cells after 48 hrs by sulforhodamine B assay, GI50 = 7.27 μM. | 23887055 | ||
| T47D | Growth inhibition assay | 48 hrs | Growth inhibition of human T47D cells after 48 hrs by sulforhodamine B assay, GI50 = 8.12 μM. | 23887055 | ||
| Hs 578T | Growth inhibition assay | 48 hrs | Growth inhibition of human Hs 578T cells after 48 hrs by sulforhodamine B assay, GI50 = 9.77 μM. | 23887055 | ||
| CCRF-CEM | Growth inhibition assay | 48 hrs | Growth inhibition of human CCRF-CEM cells after 48 hrs by sulforhodamine B assay, GI50 = 9.79 μM. | 23887055 | ||
| BT549 | Growth inhibition assay | 48 hrs | Growth inhibition of human BT549 cells after 48 hrs by sulforhodamine B assay, GI50 = 10.6 μM. | 23887055 | ||
| OVCAR5 | Growth inhibition assay | 48 hrs | Growth inhibition of human OVCAR5 cells after 48 hrs by sulforhodamine B assay, GI50 = 10.9 μM. | 23887055 | ||
| SKOV3 | Growth inhibition assay | 48 hrs | Growth inhibition of human SKOV3 cells after 48 hrs by sulforhodamine B assay, GI50 = 21.8 μM. | 23887055 | ||
| A549 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human A549 cells after 48 hrs by MTT assay, IC50 = 5.62 μM. | 23920246 | ||
| SGC7901 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human SGC7901 cells after 48 hrs by MTT assay, IC50 = 6.04 μM. | 23920246 | ||
| MDA-MB-231 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human MDA-MB-231 cells after 48 hrs by MTT assay, IC50 = 13.65 μM. | 23920246 | ||
| QGY7701 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human QGY7701 cells after 48 hrs by MTT assay, IC50 = 14.3 μM. | 23920246 | ||
| SW480 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human SW480 cells after 48 hrs by MTT assay, IC50 = 15.71 μM. | 23920246 | ||
| HeLa | Cytotoxicity assay | 48 hrs | Cytotoxicity against human HeLa cells after 48 hrs by MTT assay, IC50 = 16.52 μM. | 23920246 | ||
| A549 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human A549 cells after 72 hrs by SRB assay, GI50 = 3.6 μM. | 23964677 | ||
| SKOV3 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human SKOV3 cells after 48 hrs by MTT assay, IC50 = 24.43 μM. | 23988357 | ||
| HepG2 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay, IC50 = 29.98 μM. | 23988357 | ||
| A549 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human A549 cells after 48 hrs by MTT assay, IC50 = 34.33 μM. | 23988357 | ||
| NCI-H460 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human NCI-H460 cells after 48 hrs by MTT assay, IC50 = 44.04 μM. | 23988357 | ||
| leukemia | Cytotoxicity assay | 48 hrs | Cytotoxicity against human leukemia cells after 48 hrs by SRB assay, GI50 = 1.51 μM. | 23994328 | ||
| colon cancer | Cytotoxicity assay | 48 hrs | Cytotoxicity against human colon cancer cells after 48 hrs by SRB assay, GI50 = 8.4 μM. | 23994328 | ||
| prostate cancer | Cytotoxicity assay | 48 hrs | Cytotoxicity against human prostate cancer cells after 48 hrs by SRB assay, GI50 = 22.7 μM. | 23994328 | ||
| renal cancer | Cytotoxicity assay | 48 hrs | Cytotoxicity against human renal cancer cells after 48 hrs by SRB assay, GI50 = 45.6 μM. | 23994328 | ||
| A375-S2 | Growth inhibition assay | 48 hrs | Growth inhibition against human A375-S2 cells after 48 hrs by MTT assay, IC50 = 6.67 μM. | 23999046 | ||
| HeLa | Growth inhibition assay | 48 hrs | Growth inhibition against human HeLa cells after 48 hrs by MTT assay, IC50 = 7.34 μM. | 23999046 | ||
| HL60 | Growth inhibition assay | 48 hrs | Growth inhibition against human HL60 cells after 48 hrs by MTT assay, IC50 = 10.05 μM. | 23999046 | ||
| MCF7 | Growth inhibition assay | 48 hrs | Growth inhibition against human MCF7 cells after 48 hrs by MTT assay, IC50 = 11.5 μM. | 23999046 | ||
| K562 | Growth inhibition assay | 48 hrs | Growth inhibition against human K562 cells after 48 hrs by MTT assay, IC50 = 23.55 μM. | 23999046 | ||
| U937 | Growth inhibition assay | 48 hrs | Growth inhibition against human U937 cells after 48 hrs by MTT assay, IC50 = 23.93 μM. | 23999046 | ||
| HCT116 | Growth inhibition assay | 48 hrs | Growth inhibition against human HCT116 cells after 48 hrs by MTT assay, IC50 = 27.76 μM. | 23999046 | ||
| HT1080 | Growth inhibition assay | 48 hrs | Growth inhibition against human HT1080 cells after 48 hrs by MTT assay, IC50 = 35.62 μM. | 23999046 | ||
| HepG2 | Growth inhibition assay | 48 hrs | Growth inhibition against human HepG2 cells after 48 hrs by MTT assay, IC50 = 40.34 μM. | 23999046 | ||
| A549 | Growth inhibition assay | 48 hrs | Growth inhibition against human A549 cells after 48 hrs by MTT assay, IC50 = 44.05 μM. | 23999046 | ||
| QSG7701 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human QSG7701 cells after 48 hrs by CCK-8 assay, IC50 = 0.6 μM. | 24013415 | ||
| HepG2 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human HepG2 cells after 48 hrs by CCK-8 assay, IC50 = 12.48 μM. | 24013415 | ||
| SMMC7721 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human SMMC7721 cells after 48 hrs by CCK-8 assay, IC50 = 14.55 μM. | 24013415 | ||
| QGY7703 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human QGY7703 cells after 48 hrs by CCK-8 assay, IC50 = 15.66 μM. | 24013415 | ||
| Hep | Cytotoxicity assay | 48 hrs | Cytotoxicity against human Hep cells after 48 hrs by SRB assay, IC50 = 0.5 μM. | 24056146 | ||
| IMR32 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human IMR32 cells after 48 hrs by SRB assay, IC50 = 1.3 μM. | 24056146 | ||
| A549 | Cytotoxicity assay | 24 hrs | Cytotoxicity against human A549 cells after 24 hrs by MTT assay, IC50 = 1.1 μM. | 24060486 | ||
| HeLa | Cytotoxicity assay | 24 hrs | Cytotoxicity against human HeLa cells after 24 hrs by MTT assay, IC50 = 1.1 μM. | 24060486 | ||
| MCF7 | Cytotoxicity assay | 24 hrs | Cytotoxicity against human MCF7 cells after 24 hrs by MTT assay, IC50 = 1.2 μM. | 24060486 | ||
| DU145 | Cytotoxicity assay | 24 hrs | Cytotoxicity against human DU145 cells after 24 hrs by MTT assay, IC50 = 1.3 μM. | 24060486 | ||
| MGC803 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human MGC803 cells assessed as growth inhibition after 72 hrs by MTT assay, IC50 = 6.92 μM. | 24077182 | ||
| MCF7 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human MCF7 cells assessed as growth inhibition after 72 hrs by MTT assay, IC50 = 7.54 μM. | 24077182 | ||
| SMMC7721 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human SMMC7721 cells assessed as growth inhibition after 72 hrs by MTT assay, IC50 = 9.78 μM. | 24077182 | ||
| EC109 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human EC109 cells assessed as growth inhibition after 72 hrs by MTT assay, IC50 = 10.61 μM. | 24077182 | ||
| PC3 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human PC3 cells assessed as growth inhibition after 72 hrs by MTT assay, IC50 = 24.76 μM. | 24077182 | ||
| HCT8 | Antiproliferative assay | Antiproliferative activity against human HCT8 cells by MTT assay, IC50 = 6.92 μM. | 24095094 | |||
| Bel7402 | Antiproliferative assay | Antiproliferative activity against human Bel7402 cells by MTT assay, IC50 = 8.3 μM. | 24095094 | |||
| A549 | Antiproliferative assay | Antiproliferative activity against human A549 cells by MTT assay, IC50 = 8.92 μM. | 24095094 | |||
| SKOV3 | Cytotoxicity assay | 3 days | Cytotoxicity against human SKOV3 cells after 3 days by MTT assay, IC50 = 24.43 μM. | 24095745 | ||
| HepG2 | Cytotoxicity assay | 3 days | Cytotoxicity against human HepG2 cells after 3 days by MTT assay, IC50 = 29.98 μM. | 24095745 | ||
| A549 | Cytotoxicity assay | 3 days | Cytotoxicity against human A549 cells after 3 days by MTT assay, IC50 = 34.33 μM. | 24095745 | ||
| NCI-H460 | Cytotoxicity assay | 3 days | Cytotoxicity against human NCI-H460 cells after 3 days by MTT assay, IC50 = 44.04 μM. | 24095745 | ||
| MGC803 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human MGC803 cells after 48 hrs by MTT assay, IC50 = 3.68 μM. | 24119869 | ||
| HepG2 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay, IC50 = 4.35 μM. | 24119869 | ||
| Bcap37 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human Bcap37 cells after 48 hrs by MTT assay, IC50 = 5.58 μM. | 24119869 | ||
| SGC7901 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human SGC7901 cells after 48 hrs by MTT assay, IC50 = 7.37 μM. | 24119869 | ||
| DU145 | Cytotoxicity assay | Cytotoxic activity against human DU145 cells, IC50 = 3.4 μM. | 24195466 | |||
| NCI-H460 | Cytotoxicity assay | Cytotoxic activity against human NCI-H460 cells, IC50 = 8.5 μM. | 24195466 | |||
| HCT116 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human HCT116 cells after 72 hrs by MTT assay, IC50 = 8.32 μM. | 24211021 | ||
| MGC803 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human MGC803 cells after 72 hrs by MTT assay, IC50 = 15.32 μM. | 24211021 | ||
| HepG2 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay, IC50 = 19.45 μM. | 24211021 | ||
| A549 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human A549 cells after 72 hrs by MTT assay, IC50 = 20.13 μM. | 24211021 | ||
| NCI-H460 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human NCI-H460 cells after 72 hrs by MTT assay, IC50 = 23.32 μM. | 24211021 | ||
| SW1116 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human SW1116 cells after 48 hrs by MTT assay, IC50 = 5.26 μM. | 24286761 | ||
| HepG2 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay, IC50 = 7.43 μM. | 24286761 | ||
| BGC823 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human BGC823 cells after 48 hrs by MTT assay, IC50 = 7.48 μM. | 24286761 | ||
| MCF7 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay, IC50 = 9.79 μM. | 24286761 | ||
| MCF7 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay, IC50 = 3.5 μM. | 24332497 | ||
| B16 | Cytotoxicity assay | 48 hrs | Cytotoxicity against mouse B16 cells after 48 hrs by MTT assay, IC50 = 4.2 μM. | 24332497 | ||
| ME180 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human ME180 cells after 48 hrs by MTT assay, IC50 = 4.9 μM. | 24332497 | ||
| A549 | Cytotoxicity assay | 4 days | Cytotoxicity against human A549 cells after 4 days by MTT assay, IC50 = 3.1 μM. | 24359303 | ||
| Bel7402 | Cytotoxicity assay | 4 days | Cytotoxicity against human Bel7402 cells after 4 days by MTT assay, IC50 = 5.5 μM. | 24359303 | ||
| KB | Cytotoxicity assay | 4 days | Cytotoxicity against human KB cells after 4 days by MTT assay, IC50 = 8.1 μM. | 24359303 | ||
| HCT116 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human HCT116 cells after 48 hrs by MTT assay, IC50 = 5.78 μM. | 24378217 | ||
| HepG2 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay, IC50 = 29.98 μM. | 24378217 | ||
| HeLa | Cytotoxicity assay | 48 hrs | Cytotoxicity against human HeLa cells after 48 hrs by MTT assay, IC50 = 35.34 μM. | 24378217 | ||
| CNE | Cytotoxicity assay | 48 hrs | Cytotoxicity against human CNE cells after 48 hrs by MTT assay, IC50 = 40.21 μM. | 24378217 | ||
| SPCA2 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human SPCA2 cells after 48 hrs by MTT assay, IC50 = 42.2 μM. | 24378217 | ||
| colon cancer | Cytotoxicity assay | 10 uM | 48 hrs | Cytotoxicity against human colon cancer cells at 10 uM after 48 hrs, GI50 = 8.4 μM. | 24469112 | |
| leukemia | Cytotoxicity assay | 10 uM | 48 hrs | Cytotoxicity against human leukemia cells at 10 uM after 48 hrs, GI50 = 15.1 μM. | 24469112 | |
| prostate cancer | Cytotoxicity assay | 10 uM | 48 hrs | Cytotoxicity against human prostate cancer cells at 10 uM after 48 hrs, GI50 = 22.7 μM. | 24469112 | |
| renal cancer | Cytotoxicity assay | 10 uM | 48 hrs | Cytotoxicity against human renal cancer cells at 10 uM after 48 hrs, GI50 = 45.6 μM. | 24469112 | |
| EAC | Cytotoxicity assay | 48 hrs | Cytotoxicity against mouse EAC cells after 48 hrs by MTT assay, IC50 = 14.3 μM. | 24534537 | ||
| DLA | Cytotoxicity assay | 48 hrs | Cytotoxicity against mouse DLA cells after 48 hrs by trypan blue exclusion assay, IC50 = 14.3 μM. | 24534537 | ||
| DLA | Cytotoxicity assay | 48 hrs | Cytotoxicity against mouse DLA cells after 48 hrs by MTT assay, IC50 = 15.7 μM. | 24534537 | ||
| DLA | Cytotoxicity assay | 48 hrs | Cytotoxicity against mouse DLA cells after 48 hrs by LDH release assay, IC50 = 15.8 μM. | 24534537 | ||
| EAC | Cytotoxicity assay | 48 hrs | Cytotoxicity against mouse EAC cells after 48 hrs by LDH release assay, IC50 = 16.3 μM. | 24534537 | ||
| EAC | Cytotoxicity assay | 48 hrs | Cytotoxicity against mouse EAC cells after 48 hrs by trypan blue exclusion assay, IC50 = 16.4 μM. | 24534537 | ||
| HeLa | Cytotoxicity assay | 48 hrs | Cytotoxicity against human HeLa cells after 48 hrs by MTT assay, IC50 = 2.3 μM. | 24547794 | ||
| HepG2 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay, IC50 = 7.6 μM. | 24547794 | ||
| HCT116 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human HCT116 cells after 48 hrs by MTT assay, IC50 = 24.43 μM. | 24565905 | ||
| SKOV3 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human SKOV3 cells after 48 hrs by MTT assay, IC50 = 24.43 μM. | 24565905 | ||
| Bel7404 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human Bel7404 cells after 48 hrs by MTT assay, IC50 = 26.8 μM. | 24565905 | ||
| HepG2 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay, IC50 = 26.98 μM. | 24565905 | ||
| NCI-H460 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human NCI-H460 cells after 48 hrs by MTT assay, IC50 = 36.04 μM. | 24565905 | ||
| H3347 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human H3347 cells assessed as growth inhibition after 72 hrs by Alamar Blue assay, IC50 = 11.64 μM. | 24583355 | ||
| HT-29 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human HT-29 cells assessed as growth inhibition after 72 hrs by Alamar Blue assay, IC50 = 24.87 μM. | 24583355 | ||
| DLD1 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human DLD1 cells assessed as growth inhibition after 72 hrs by Alamar Blue assay, IC50 = 29.14 μM. | 24583355 | ||
| L1210 | Cytotoxicity assay | 48 hrs | Cytotoxicity against mouse L1210 cells assessed as reduction in cell number after 48 hrs by cell counting assay, IC50 = 0.33 μM. | 24631358 | ||
| HeLa | Cytotoxicity assay | 72 hrs | Cytotoxicity against human HeLa cells assessed as reduction in cell number after 72 hrs by cell counting assay, IC50 = 0.54 μM. | 24631358 | ||
| CCRF-CEM | Cytotoxicity assay | 72 hrs | Cytotoxicity against human CCRF-CEM cells assessed as reduction in cell number after 72 hrs by cell counting assay, IC50 = 18 μM. | 24631358 | ||
| HeLa | Cytotoxicity assay | 24 hrs | Cytotoxicity against human HeLa cells assessed as growth inhibition after 24 hrs by MTT assay, IC50 = 1.8 μM. | 24641975 | ||
| MCF7 | Cytotoxicity assay | 24 hrs | Cytotoxicity against human MCF7 cells assessed as growth inhibition after 24 hrs by MTT assay, IC50 = 1.8 μM. | 24641975 | ||
| A549 | Cytotoxicity assay | 24 hrs | Cytotoxicity against human A549 cells assessed as growth inhibition after 24 hrs by MTT assay, IC50 = 1.9 μM. | 24641975 | ||
| DU145 | Cytotoxicity assay | 24 hrs | Cytotoxicity against human DU145 cells assessed as growth inhibition after 24 hrs by MTT assay, IC50 = 1.9 μM. | 24641975 | ||
| COLO205 | Cytotoxicity assay | 24 hrs | Cytotoxicity against human COLO205 cells assessed as inhibition of tumor growth after 24 hrs, IC50 = 3.39 μM. | 24657568 | ||
| RPMI8226 | Antileukemic assay | 24 hrs | Antileukemic activity against human RPMI8226 cells assessed as inhibition of tumor growth after 24 hrs, IC50 = 3.55 μM. | 24657568 | ||
| HCC2998 | Cytotoxicity assay | 24 hrs | Cytotoxicity against human HCC2998 cells assessed as inhibition of tumor growth after 24 hrs, IC50 = 5.75 μM. | 24657568 | ||
| HCT15 | Cytotoxicity assay | 24 hrs | Cytotoxicity against human HCT15 cells assessed as inhibition of tumor growth after 24 hrs, IC50 = 6.61 μM. | 24657568 | ||
| KM12 | Cytotoxicity assay | 24 hrs | Cytotoxicity against human KM12 cells assessed as inhibition of tumor growth after 24 hrs, IC50 = 7.94 μM. | 24657568 | ||
| SW620 | Cytotoxicity assay | 24 hrs | Cytotoxicity against human SW620 cells assessed as inhibition of tumor growth after 24 hrs, IC50 = 18.6 μM. | 24657568 | ||
| NCI60 | Cytotoxicity assay | 24 hrs | Cytotoxicity against human NCI60 cells assessed as inhibition of tumor growth after 24 hrs, IC50 = 29.5 μM. | 24657568 | ||
| E0771 | Cytotoxicity assay | 3 days | Cytotoxicity against mouse E0771 cells after 3 days by SRB assay, IC50 = 0.28 μM. | 24704691 | ||
| HT-29 | Cytotoxicity assay | 3 days | Cytotoxicity against human HT-29 cells after 3 days by SRB assay, IC50 = 2.58 μM. | 24704691 | ||
| MCF7 | Cytotoxicity assay | 3 days | Cytotoxicity against human MCF7 cells after 3 days by SRB assay, IC50 = 2.86 μM. | 24704691 | ||
| SW480 | Cytotoxicity assay | 3 days | Cytotoxicity against human SW480 cells after 3 days by SRB assay, IC50 = 3.69 μM. | 24704691 | ||
| RKO | Cytotoxicity assay | 3 days | Cytotoxicity against human RKO cells after 3 days by SRB assay, IC50 = 4.39 μM. | 24704691 | ||
| MCF10A | Cytotoxicity assay | 3 days | Cytotoxicity against human MCF10A cells after 3 days by SRB assay, IC50 = 8.06 μM. | 24704691 | ||
| CCD-18Co | Cytotoxicity assay | 3 days | Cytotoxicity against human CCD-18Co cells after 3 days by SRB assay, IC50 = 9.26 μM. | 24704691 | ||
| T47D | Cytotoxicity assay | 3 days | Cytotoxicity against human T47D cells after 3 days by SRB assay, IC50 = 10.56 μM. | 24704691 | ||
| MDA-MB-231 | Cytotoxicity assay | 3 days | Cytotoxicity against human MDA-MB-231 cells after 3 days by SRB assay, IC50 = 18.12 μM. | 24704691 | ||
| A549 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human A549 cells assessed as growth inhibition measured at 48 hrs by SRB assay, IC50 = 0.98 μM. | 24727462 | ||
| HeLa | Cytotoxicity assay | 2 days | Cytotoxicity against human HeLa cells after 2 days by MTT assay, IC50 = 7.34 μM. | 24767839 | ||
| MCF7 | Cytotoxicity assay | 2 days | Cytotoxicity against human MCF7 cells after 2 days by MTT assay, IC50 = 11.5 μM. | 24767839 | ||
| HT-29 | Cytotoxicity assay | 2 days | Cytotoxicity against human HT-29 cells after 2 days by MTT assay, IC50 = 17.2 μM. | 24767839 | ||
| A549 | Cytotoxicity assay | 2 days | Cytotoxicity against human A549 cells after 2 days by MTT assay, IC50 = 44.05 μM. | 24767839 | ||
| A549 | Growth inhibition assay | 48 hrs | Growth inhibition of human A549 cells after 48 hrs by SRB assay, GI50 = 4.55 μM. | 24797798 | ||
| PC3 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human PC3 cells after 72 hrs by MTT assay, IC50 = 4.68 μM. | 24798098 | ||
| MCF7 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay, IC50 = 7.76 μM. | 24798098 | ||
| MGC803 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human MGC803 cells after 72 hrs by MTT assay, IC50 = 8.13 μM. | 24798098 | ||
| EC109 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human EC109 cells after 72 hrs by MTT assay, IC50 = 24.14 μM. | 24798098 | ||
| MCF7 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay, IC50 = 7.08 μM. | 24819956 | ||
| HCT116 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay, IC50 = 10.54 μM. | 24819956 | ||
| Bel7402 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human Bel7402 cells after 72 hrs by MTT assay, IC50 = 11.12 μM. | 24819956 | ||
| A549 | Cytotoxicity assay | 24 hrs | Cytotoxicity against human A549 cells after 24 hrs by MTT assay, IC50 = 1.3 μM. | 24835633 | ||
| HeLa | Cytotoxicity assay | 24 hrs | Cytotoxicity against human HeLa cells after 24 hrs by MTT assay, IC50 = 1.3 μM. | 24835633 | ||
| MCF7 | Cytotoxicity assay | 24 hrs | Cytotoxicity against human MCF7 cells after 24 hrs by MTT assay, IC50 = 1.4 μM. | 24835633 | ||
| DU145 | Cytotoxicity assay | 24 hrs | Cytotoxicity against human DU145 cells after 24 hrs by MTT assay, IC50 = 1.5 μM. | 24835633 | ||
| MCF7 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay, IC50 = 3.52 μM. | 24835817 | ||
| EC9706 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human EC9706 cells after 48 hrs by MTT assay, IC50 = 9.45 μM. | 24835817 | ||
| MGC803 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human MGC803 cells after 48 hrs by MTT assay, IC50 = 11.34 μM. | 24835817 | ||
| L1210 | Cytostatic activity assay | 48 hrs | Cytostatic activity against mouse L1210 cells assessed as inhibition of proliferation after 48 hrs by Coulter cell counting method, IC50 = 0.33 μM. | 24906510 | ||
| HeLa | Cytostatic activity assay | 72 hrs | Cytostatic activity against human HeLa cells assessed as inhibition of proliferation after 72 hrs by Coulter cell counting method, IC50 = 0.54 μM. | 24906510 | ||
| CEM | Cytostatic activity assay | 72 hrs | Cytostatic activity against human CEM cells assessed as inhibition of proliferation after 72 hrs by Coulter cell counting method, IC50 = 18 μM. | 24906510 | ||
| PC3 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human PC3 cells after 48 hrs by sulforhodamine B assay, IC50 = 2.2 μM. | 24910974 | ||
| HCT15 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human HCT15 cells after 48 hrs by sulforhodamine B assay, IC50 = 4.5 μM. | 24910974 | ||
| HeLa | Cytotoxicity assay | 48 hrs | Cytotoxicity against human HeLa cells after 48 hrs by sulforhodamine B assay, IC50 = 4.9 μM. | 24910974 | ||
| WM266.4 | Antiproliferative assay | 24 hrs | Antiproliferative activity against human WM266.4 cells after 24 hrs by MTT assay, GI50 = 28.76 μM. | 24934992 | ||
| HeLa | Antiproliferative assay | 24 hrs | Antiproliferative activity against human HeLa cells after 24 hrs by MTT assay, GI50 = 30.21 μM. | 24934992 | ||
| MDA-MB-231 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay, IC50 = 2.45 μM. | 24941129 | ||
| HeLa | Antiproliferative assay | 48 hrs | Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay, IC50 = 2.78 μM. | 24941129 | ||
| KCL22 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human KCL22 cells after 48 hrs by MTT assay, IC50 = 3.52 μM. | 24941129 | ||
| KB | Cytotoxicity assay | 48 hrs | Cytotoxicity against human KB cells after 48 hrs by MTT assay, IC50 = 1.23 μM. | 24953029 | ||
| HCT116 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human HCT116 cells after 48 hrs by MTT assay, IC50 = 10.05 μM. | 24953029 | ||
| HeLa | Cytotoxicity assay | 48 hrs | Cytotoxicity against human HeLa cells after 48 hrs by MTT assay, IC50 = 23.33 μM. | 24953029 | ||
| A549 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human A549 cells after 48 hrs by MTT assay, IC50 = 34.34 μM. | 24953029 | ||
| HepG2 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay, IC50 = 38.34 μM. | 24953029 | ||
| CNE | Cytotoxicity assay | 48 hrs | Cytotoxicity against human CNE cells after 48 hrs by MTT assay, IC50 = 45.1 μM. | 24953029 | ||
| NCI-H460 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human NCI-H460 cells after 48 hrs by MTT assay, IC50 = 45.14 μM. | 24953029 | ||
| MGC803 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human MGC803 cells after 48 hrs by MTT assay, IC50 = 46.93 μM. | 24953029 | ||
| A549 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human A549 cells after 48 hrs by sulforhodamine B assay, IC50 = 4.21 μM. | 24956552 | ||
| PC3 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human PC3 cells after 48 hrs by sulforhodamine B assay, IC50 = 12 μM. | 24956552 | ||
| A549 | Cytotoxicity assay | 24 to 48 hrs | Cytotoxicity against human A549 cells assessed as growth inhibition after 24 to 48 hrs by sulforhodamine B assay, IC50 = 1.65 μM. | 24996138 | ||
| MGC803 | Anticancer assay | 72 hrs | Anticancer activity against human MGC803 cells after 72 hrs by MTT assay, IC50 = 3.45 μM. | 25001482 | ||
| MCF7 | Anticancer assay | 72 hrs | Anticancer activity against human MCF7 cells after 72 hrs by MTT assay, IC50 = 7.12 μM. | 25001482 | ||
| EC9706 | Anticancer assay | 72 hrs | Anticancer activity against human EC9706 cells after 72 hrs by MTT assay, IC50 = 8.07 μM. | 25001482 | ||
| SSMC-7721 | Anticancer assay | 72 hrs | Anticancer activity against human SSMC-7721 cells after 72 hrs by MTT assay, IC50 = 15.08 μM. | 25001482 | ||
| MDA-MB-231 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human MDA-MB-231 cells after 48 hrs by MTT assay, IC50 = 24.6 μM. | 25016234 | ||
| A549 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human A549 cells after 48 hrs by MTT assay, IC50 = 35.41 μM. | 25016234 | ||
| MCF7 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay, IC50 = 39.88 μM. | 25016234 | ||
| HepG2 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay, IC50 = 46.83 μM. | 25016234 | ||
| HCT116 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human HCT116 cells after 72 hrs by MTS assay, IC50 = 0.5 μM. | 25066282 | ||
| SW620 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human SW620 cells after 72 hrs by MTS assay, IC50 = 5.3 μM. | 25066282 | ||
| MCF7 | Anticancer assay | 72 hrs | Anticancer activity against human MCF7 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay, IC50 = 4.6 μM. | 25086915 | ||
| EC9706 | Anticancer assay | 72 hrs | Anticancer activity against human EC9706 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay, IC50 = 4.7 μM. | 25086915 | ||
| MGC803 | Anticancer assay | 72 hrs | Anticancer activity against human MGC803 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay, IC50 = 10 μM. | 25086915 | ||
| HeLa | Anticancer assay | 72 hrs | Anticancer activity against human HeLa cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay, IC50 = 12 μM. | 25086915 | ||
| A549 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human A549 cells assessed as inhibition of cell viability after 48 hrs by MTT assay, IC50 = 7.62 μM. | 25113877 | ||
| MGC803 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human MGC803 cells assessed as inhibition of cell viability after 48 hrs by MTT assay, IC50 = 7.76 μM. | 25113877 | ||
| CNE | Antiproliferative assay | 48 hrs | Antiproliferative activity against human CNE cells assessed as inhibition of cell viability after 48 hrs by MTT assay, IC50 = 15.07 μM. | 25113877 | ||
| Bel7402 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human Bel7402 cells assessed as inhibition of cell viability after 48 hrs by MTT assay, IC50 = 19.84 μM. | 25113877 | ||
| HepG2 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay, IC50 = 29.98 μM. | 25151580 | ||
| HeLa | Cytotoxicity assay | 48 hrs | Cytotoxicity against human HeLa cells after 48 hrs by MTT assay, IC50 = 35.34 μM. | 25151580 | ||
| SMMC-7404 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human SMMC-7404 cells after 48 hrs by MTT assay, IC50 = 40.21 μM. | 25151580 | ||
| NCI-H460 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human NCI-H460 cells after 48 hrs by MTT assay, IC50 = 44.04 μM. | 25151580 | ||
| MGC803 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human MGC803 cells after 48 hrs by MTT assay, IC50 = 46.93 μM. | 25151580 | ||
| B16 | Antiproliferative assay | 48 hrs | Antiproliferative activity against mouse B16 cells after 48 hrs by MTT assay, IC50 = 17.85 μM. | 25164762 | ||
| HL60 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human HL60 cells after 48 hrs by MTT assay, IC50 = 27.01 μM. | 25164762 | ||
| Hep | Cytotoxicity assay | 48 hrs | Cytotoxicity against human Hep cells after 48 hrs by SRB assay, IC50 = 0.5 μM. | 25176329 | ||
| IMR32 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human IMR32 cells after 48 hrs by SRB assay, IC50 = 1.3 μM. | 25176329 | ||
| B16F10 | Cytotoxicity assay | 72 hrs | Cytotoxicity against mouse B16F10 cells assessed as inhibition of proliferation after 72 hrs by MTT assay, IC50 = 0.87 μM. | 25180925 | ||
| MGC803 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human MGC803 cells assessed as inhibition of proliferation after 72 hrs by MTT assay, IC50 = 7.69 μM. | 25180925 | ||
| MCF7 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human MCF7 cells assessed as inhibition of proliferation after 72 hrs by MTT assay, IC50 = 8.93 μM. | 25180925 | ||
| EC109 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human EC109 cells assessed as inhibition of proliferation after 72 hrs by MTT assay, IC50 = 10.81 μM. | 25180925 | ||
| HEK293 | Antiproliferative assay | 24 hrs | Antiproliferative activity against HEK293 cells after 24 hrs by MTT assay, IC50 = 48.7 μM. | 25198997 | ||
| Bel7402 | Cytotoxicity assay | 96 hrs | Cytotoxicity against human Bel7402 cells assessed as growth inhibition rate after 96 hrs by MTT assay, IC50 = 2.23 μM. | 25203783 | ||
| HCT8 | Cytotoxicity assay | 96 hrs | Cytotoxicity against human HCT8 cells assessed as growth inhibition rate after 96 hrs by MTT assay, IC50 = 3.54 μM. | 25203783 | ||
| C33A | Cytotoxicity assay | 96 hrs | Cytotoxicity against human C33A cells assessed as growth inhibition rate after 96 hrs by MTT assay, IC50 = 4.61 μM. | 25203783 | ||
| A549 | Cytotoxicity assay | 96 hrs | Cytotoxicity against human A549 cells assessed as growth inhibition rate after 96 hrs by MTT assay, IC50 = 6.69 μM. | 25203783 | ||
| A549 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human A549 cells after 48 hrs by SRB assay, IC50 = 0.01 μM. | 25259515 | ||
| THP1 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human THP1 cells after 48 hrs by SRB assay, IC50 = 0.04 μM. | 25259515 | ||
| EAC | Cytotoxicity assay | 48 hrs | Cytotoxicity against mouse EAC cells after 48 hrs by trypan blue dye exclusion method, IC50 = 14.6 μM. | 25261825 | ||
| DLA | Cytotoxicity assay | 48 hrs | Cytotoxicity against mouse DLA cells after 48 hrs by trypan blue dye exclusion method, IC50 = 15.3 μM. | 25261825 | ||
| EAC | Cytotoxicity assay | 48 hrs | Cytotoxicity against mouse EAC cells after 48 hrs by LDH release assay, IC50 = 15.4 μM. | 25261825 | ||
| DLA | Cytotoxicity assay | 48 hrs | Cytotoxicity against mouse DLA cells after 48 hrs by MTT method, IC50 = 15.6 μM. | 25261825 | ||
| EAC | Cytotoxicity assay | 48 hrs | Cytotoxicity against mouse EAC cells after 48 hrs by MTT method, IC50 = 16.3 μM. | 25261825 | ||
| DLA | Cytotoxicity assay | 48 hrs | Cytotoxicity against mouse DLA cells after 48 hrs by LDH release assay, IC50 = 16.8 μM. | 25261825 | ||
| L1210 | Cytostatic activity assay | 48 hrs | Cytostatic activity against mouse L1210 cells after 48 hrs by Coulter counting, IC50 = 0.33 μM. | 25435471 | ||
| HeLa | Cytostatic activity assay | 72 hrs | Cytostatic activity against human HeLa cells after 72 hrs by Coulter counting, IC50 = 2.6 μM. | 25435471 | ||
| CEM | Cytostatic activity assay | 72 hrs | Cytostatic activity against human CEM cells after 72 hrs by Coulter counting, IC50 = 18 μM. | 25435471 | ||
| SMMC7721 | Antiproliferative assay | Antiproliferative activity against human SMMC7721 cells assessed as inhibition of cell proliferation by CCK8 assay, IC50 = 5.62 μM. | 25442303 | |||
| A549 | Antiproliferative assay | Antiproliferative activity against human A549 cells assessed as inhibition of cell proliferation by CCK8 assay, IC50 = 8.13 μM. | 25442303 | |||
| MCF7 | Antiproliferative assay | Antiproliferative activity against human MCF7 cells assessed as inhibition of cell proliferation by CCK8 assay, IC50 = 14.26 μM. | 25442303 | |||
| LoVo | Antiproliferative assay | 48 hrs | Antiproliferative activity against human LoVo cells assessed as cell-growth inhibition after 48 hrs by MTT assay, IC50 = 12.7 μM. | 25453794 | ||
| MCF7 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human MCF7 cells assessed as cell-growth inhibition after 48 hrs by MTT assay, IC50 = 16.3 μM. | 25453794 | ||
| HeLa | Antiproliferative assay | 48 hrs | Antiproliferative activity against human HeLa cells assessed as cell-growth inhibition after 48 hrs by MTT assay, IC50 = 18.1 μM. | 25453794 | ||
| BGC823 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human BGC823 cells assessed as cell-growth inhibition after 48 hrs by MTT assay, IC50 = 35.6 μM. | 25453794 | ||
| HCT116 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human HCT116 cells assessed as cell-growth inhibition after 48 hrs by MTT assay, IC50 = 36.2 μM. | 25453794 | ||
| U87 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human U87 cells assessed as cell-growth inhibition after 48 hrs by MTT assay, IC50 = 38.2 μM. | 25453794 | ||
| MGC803 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human MGC803 cells after 48 hrs by MTT assay, IC50 = 30.45 μM. | 25462253 | ||
| NCI-H460 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human NCI-H460 cells after 48 hrs by MTT assay, IC50 = 36.04 μM. | 25462253 | ||
| HeLa | Cytotoxicity assay | 48 hrs | Cytotoxicity against human HeLa cells after 48 hrs by MTT assay, IC50 = 36.53 μM. | 25462253 | ||
| MCF7 | Anticancer assay | 48 hrs | Anticancer activity against human MCF7 cells after 48 hrs by MTT assay, IC50 = 26.9 μM. | 25462264 | ||
| GES-1 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human GES-1 cells after 48 hrs by MTT assay, IC50 = 30.9 μM. | 25462264 | ||
| K562 | Anticancer assay | 48 hrs | Anticancer activity against human K562 cells after 48 hrs by MTT assay, IC50 = 31.6 μM. | 25462264 | ||
| HCT116 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human HCT116 cells after 72 hrs by SRB assay, IC50 = 6 μM. | 25462277 | ||
| T47D | Cytotoxicity assay | 72 hrs | Cytotoxicity against human T47D cells after 72 hrs by SRB assay, IC50 = 7.9 μM. | 25462277 | ||
| HuH7 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human HuH7 cells after 72 hrs by SRB assay, IC50 = 30.7 μM. | 25462277 | ||
| MCF7 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human MCF7 cells assessed as cell growth inhibition after 48 hrs by WST-1 assay, IC50 = 34.48 μM. | 25466196 | ||
| SKBR3 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human SKBR3 cells overexpressing HER2 assessed as cell growth inhibition after 48 hrs by WST-1 assay, IC50 = 38.88 μM. | 25466196 | ||
| B16 | Cytotoxicity assay | 48 hrs | Cytotoxicity against mouse B16 cells assessed as cell survival after 48 hrs by MTT assay, IC50 = 7.64 μM. | 25506718 | ||
| MKN28 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human MKN28 cells assessed as cell survival after 48 hrs by MTT assay, IC50 = 9.67 μM. | 25506718 | ||
| HeLa | Cytotoxicity assay | 48 hrs | Cytotoxicity against human HeLa cells assessed as cell survival after 48 hrs by MTT assay, IC50 = 13.45 μM. | 25506718 | ||
| HeLa | Antiproliferative assay | 72 hrs | Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay, IC50 = 9.09 μM. | 25529742 | ||
| SF763 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human SF763 cells after 72 hrs by MTT assay, IC50 = 9.34 μM. | 25529742 | ||
| HL60 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human HL60 cells after 72 hrs by MTT assay, IC50 = 10.45 μM. | 25529742 | ||
| B16 | Antiproliferative assay | 72 hrs | Antiproliferative activity against mouse B16 cells after 72 hrs by MTT assay, IC50 = 10.52 μM. | 25529742 | ||
| Bel7402 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human Bel7402 cells after 72 hrs by MTT assay, IC50 = 11.78 μM. | 25529742 | ||
| MGC803 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human MGC803 cells after 48 hrs by MTT assay, IC50 = 3.71 μM. | 25554922 | ||
| Bcap37 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human Bcap37 cells after 48 hrs by MTT assay, IC50 = 5.18 μM. | 25554922 | ||
| SGC7901 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human SGC7901 cells after 48 hrs by MTT assay, IC50 = 6.56 μM. | 25554922 | ||
| BALB/3T3 | Antiproliferative assay | 72 hrs | Antiproliferative activity against mouse BALB/3T3 cells assessed as growth inhibition after 72 hrs by SRB method, IC50 = 3.23 μM. | 25644674 | ||
| LoVo | Antiproliferative assay | 72 hrs | Antiproliferative activity against human LoVo cells assessed as growth inhibition after 72 hrs by SRB method, IC50 = 4.69 μM. | 25644674 | ||
| doxorubicin-resistant LoVo/DX | Antiproliferative assay | 72 hrs | Antiproliferative activity against human doxorubicin-resistant LoVo/DX cells assessed as growth inhibition after 72 hrs by SRB method, IC50 = 6 μM. | 25644674 | ||
| SW707 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human SW707 cells assessed as growth inhibition after 72 hrs by SRB method, IC50 = 20.46 μM. | 25644674 | ||
| vincristine-resistant HL60/Vinc | Antiproliferative assay | 72 hrs | Antiproliferative activity against human vincristine-resistant HL60/Vinc cells assessed as growth inhibition after 72 hrs by MTT assay, IC50 = 21.15 μM. | 25644674 | ||
| HL60 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human HL60 cells assessed as growth inhibition after 72 hrs by MTT assay, IC50 = 22.54 μM. | 25644674 | ||
| HT-29 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human HT-29 cells assessed as growth inhibition after 72 hrs by SRB method, IC50 = 25.08 μM. | 25644674 | ||
| LS180 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human LS180 cells assessed as growth inhibition after 72 hrs by SRB method, IC50 = 38.92 μM. | 25644674 | ||
| B16F10 | Anticancer assay | 72 hrs | Anticancer activity against mouse B16F10 cells assessed as inhibition of proliferation after 72 hrs by MTT assay, IC50 = 1.43 μM. | 25655718 | ||
| MGC803 | Anticancer assay | 72 hrs | Anticancer activity against human MGC803 cells assessed as inhibition of proliferation after 72 hrs by MTT assay, IC50 = 8.43 μM. | 25655718 | ||
| MCF7 | Anticancer assay | 72 hrs | Anticancer activity against human MCF7 cells assessed as inhibition of proliferation after 72 hrs by MTT assay, IC50 = 9.12 μM. | 25655718 | ||
| EC109 | Anticancer assay | 72 hrs | Anticancer activity against human EC109 cells assessed as inhibition of proliferation after 72 hrs by MTT assay, IC50 = 11.61 μM. | 25655718 | ||
| HCT8 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human HCT8 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay, IC50 = 0.91 μM. | 25675144 | ||
| HCT8 | Antiproliferative assay | 72 hrs | Antiproliferative activity against 5-FU resistant human HCT8 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay, IC50 = 36.638 μM. | 25675144 | ||
| MGC803 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human MGC803 cells after 72 hrs by MTT assay, IC50 = 10.72 μM. | 25707012 | ||
| MCF7 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay, IC50 = 12.24 μM. | 25707012 | ||
| EC9706 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human EC9706 cells after 72 hrs by MTT assay, IC50 = 15.67 μM. | 25707012 | ||
| SMMC7721 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human SMMC7721 cells after 72 hrs by MTT assay, IC50 = 20.4 μM. | 25707012 | ||
| SW1573 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human SW1573 cells after 48 hrs by sulforhodamine B assay, GI50 = 4.3 μM. | 25752525 | ||
| HBL100 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human HBL100 cells after 48 hrs by sulforhodamine B assay, GI50 = 5.5 μM. | 25752525 | ||
| HeLa | Antiproliferative assay | 48 hrs | Antiproliferative activity against human HeLa cells after 48 hrs by sulforhodamine B assay, GI50 = 15 μM. | 25752525 | ||
| T47D | Antiproliferative assay | 48 hrs | Antiproliferative activity against human T47D cells after 48 hrs by sulforhodamine B assay, GI50 = 47 μM. | 25752525 | ||
| WiDr | Antiproliferative assay | 48 hrs | Antiproliferative activity against human WiDr cells after 48 hrs by sulforhodamine B assay, GI50 = 49 μM. | 25752525 | ||
| MGC803 | Anticancer assay | 48 hrs | Anticancer activity against human MGC803 cells assessed as cell survival after 48 hrs by MTT assay, IC50 = 3.58 μM. | 25812966 | ||
| SMMC7721 | Anticancer assay | 48 hrs | Anticancer activity against human SMMC7721 cells assessed as cell survival after 48 hrs by MTT assay, IC50 = 4.87 μM. | 25812966 | ||
| HepG2 | Anticancer assay | 48 hrs | Anticancer activity against human HepG2 cells assessed as cell survival after 48 hrs by MTT assay, IC50 = 5.86 μM. | 25812966 | ||
| SGC7901 | Anticancer assay | 48 hrs | Anticancer activity against human SGC7901 cells assessed as cell survival after 48 hrs by MTT assay, IC50 = 6.12 μM. | 25812966 | ||
| SKOV3 | Cytotoxicity assay | 2 days | Cytotoxicity against human SKOV3 cells after 2 days by MTT assay, IC50 = 27.34 μM. | 25841196 | ||
| HepG2 | Cytotoxicity assay | 2 days | Cytotoxicity against human HepG2 cells after 2 days by MTT assay, IC50 = 31.98 μM. | 25841196 | ||
| A549 | Cytotoxicity assay | 2 days | Cytotoxicity against human A549 cells after 2 days by MTT assay, IC50 = 38.23 μM. | 25841196 | ||
| T24 | Cytotoxicity assay | 2 days | Cytotoxicity against human T24 cells after 2 days by MTT assay, IC50 = 40.57 μM. | 25841196 | ||
| SPCA2 | Cytotoxicity assay | 2 days | Cytotoxicity against human SPCA2 cells after 2 days by MTT assay, IC50 = 44.1 μM. | 25841196 | ||
| NCI-H460 | Cytotoxicity assay | 2 days | Cytotoxicity against human NCI-H460 cells after 2 days by MTT assay, IC50 = 46.15 μM. | 25841196 | ||
| MGC803 | Cytotoxicity assay | 2 days | Cytotoxicity against human MGC803 cells after 2 days by MTT assay, IC50 = 47.39 μM. | 25841196 | ||
| HCT116 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human HCT116 cells assessed as cell viability after 48 hrs by MTT assay, IC50 = 29.58 μM. | 25841199 | ||
| HepG2 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human HepG2 cells assessed as cell viability after 48 hrs by MTT assay, IC50 = 30.79 μM. | 25841199 | ||
| A549 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human A549 cells assessed as cell viability after 48 hrs by MTT assay, IC50 = 36.34 μM. | 25841199 | ||
| T24 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human T24 cells assessed as cell viability after 48 hrs by MTT assay, IC50 = 37.56 μM. | 25841199 | ||
| MGC803 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human MGC803 cells assessed as cell viability after 48 hrs by MTT assay, IC50 = 40.94 μM. | 25841199 | ||
| MDA-MB-231 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human MDA-MB-231 cells after 48 hrs by MTT assay, IC50 = 5.82 μM. | 25870131 | ||
| DU145 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human DU145 cells after 48 hrs by MTT assay, IC50 = 6.37 μM. | 25870131 | ||
| A549 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human A549 cells after 48 hrs by MTT assay, IC50 = 7.51 μM. | 25870131 | ||
| A549 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human A549 cells after 72 hrs by WST8 assay, IC50 = 2.8 μM. | 25919052 | ||
| PANC1 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human PANC1 cells after 72 hrs by WST8 assay, IC50 = 3.7 μM. | 25919052 | ||
| PSN1 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human PSN1 cells after 72 hrs by WST8 assay, IC50 = 4.4 μM. | 25919052 | ||
| MDA-MB-231 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by WST8 assay, IC50 = 5.2 μM. | 25919052 | ||
| HeLa | Antiproliferative assay | 72 hrs | Antiproliferative activity against human HeLa cells after 72 hrs by WST8 assay, IC50 = 5.8 μM. | 25919052 | ||
| TIG3 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human TIG3 cells after 72 hrs by WST8 assay, IC50 = 8.4 μM. | 25919052 | ||
| HeLa | Antiproliferative assay | 48 hrs | Antiproliferative activity against human HeLa cells assessed as inhibition of cell proliferation incubated for 48 hrs by CCK8 assay, IC50 = 8.93 μM. | 25959813 | ||
| MCF7 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human MCF7 cells assessed as inhibition of cell proliferation incubated for 48 hrs by CCK8 assay, IC50 = 9.56 μM. | 25959813 | ||
| Bel7402 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human Bel7402 cells assessed as inhibition of cell proliferation incubated for 48 hrs by CCK8 assay, IC50 = 19.91 μM. | 25959813 | ||
| NIH/3T3 | Antiproliferative assay | 48 hrs | Antiproliferative activity against mouse NIH/3T3 cells assessed as inhibition of cell proliferation incubated for 48 hrs by CCK8 assay, IC50 = 22.36 μM. | 25959813 | ||
| A549 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human A549 cells assessed as inhibition of cell proliferation incubated for 48 hrs by CCK8 assay, IC50 = 40.38 μM. | 25959813 | ||
| HepG2 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay, IC50 = 8 μM. | 25969171 | ||
| L1210 | Cytotoxicity assay | Cytotoxicity against mouse L1210 cells assessed as inhibition of cell proliferation, IC50 = 0.33 μM. | 26001344 | |||
| HeLa | Cytotoxicity assay | Cytotoxicity against human HeLa cells assessed as inhibition of cell proliferation, IC50 = 0.54 μM. | 26001344 | |||
| CEM | Cytotoxicity assay | Cytotoxicity against human CEM cells assessed as inhibition of cell proliferation, IC50 = 18 μM. | 26001344 | |||
| PC3 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human PC3 cells assessed as growth inhibition after 48 hrs by sulphorhodamine B assay, IC50 = 2.2 μM. | 26222449 | ||
| HCT116 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human HCT116 cells assessed as growth inhibition after 48 hrs by sulphorhodamine B assay, IC50 = 4.5 μM. | 26222449 | ||
| A549 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human A549 cells assessed as growth inhibition after 48 hrs by sulphorhodamine B assay, IC50 = 4.9 μM. | 26222449 | ||
| HCT8 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human HCT8 cells after 72 hrs by MTT assay, IC50 = 6.3 μM. | 26227777 | ||
| Bel7402 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human Bel7402 cells after 72 hrs by MTT assay, IC50 = 10.07 μM. | 26227777 | ||
| A549 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human A549 cells after 72 hrs by MTT assay, IC50 = 14.15 μM. | 26227777 | ||
| HepG2 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay, IC50 = 16.42 μM. | 26227777 | ||
| A549 | Anticancer assay | 48 hrs | Anticancer activity against human A549 cells assessed as reduction in cell growth incubated for 48 hrs by MTT assay, IC50 = 2.13 μM. | 26231080 | ||
| MCF7 | Anticancer assay | 48 hrs | Anticancer activity against human MCF7 cells assessed as reduction in cell growth incubated for 48 hrs by MTT assay, IC50 = 2.36 μM. | 26231080 | ||
| HeLa | Anticancer assay | 48 hrs | Anticancer activity against human HeLa cells assessed as reduction in cell growth incubated for 48 hrs by MTT assay, IC50 = 4.6 μM. | 26231080 | ||
| HaCaT | Cytotoxicity assay | 48 hrs | Cytotoxic activity against human HaCaT cells assessed as reduction in cell growth incubated for 48 hrs by MTT assay, IC50 = 15.26 μM. | 26231080 | ||
| Hep3B | Cytotoxicity assay | 2 days | Cytotoxicity against human Hep3B cells assessed as induction of cell death incubated for 2 days by MTT assay, IC50 = 1.5 μM. | 26259802 | ||
| Bcap37 | Cytotoxicity assay | 2 days | Cytotoxicity against human Bcap37 cells assessed as induction of cell death incubated for 2 days by MTT assay, IC50 = 5.58 μM. | 26259802 | ||
| MCF7 | Cytotoxicity assay | 2 days | Cytotoxicity against human MCF7 cells assessed as induction of cell death incubated for 2 days by MTT assay, IC50 = 11.5 μM. | 26259802 | ||
| HepG2 | Cytotoxicity assay | 2 days | Cytotoxicity against human HepG2 cells assessed as induction of cell death incubated for 2 days by MTT assay, IC50 = 40.34 μM. | 26259802 | ||
| A549 | Cytotoxicity assay | 2 days | Cytotoxicity against human A549 cells assessed as induction of cell death incubated for 2 days by MTT assay, IC50 = 44.05 μM. | 26259802 | ||
| SW620 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human SW620 cells incubated for 72 hrs by MTT assay, IC50 = 0.79 μM. | 26291038 | ||
| MIAPaCa2 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human MIAPaCa2 cells incubated for 72 hrs by MTT assay, IC50 = 11.67 μM. | 26291038 | ||
| MCF7 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay, IC50 = 5.012 μM. | 26301558 | ||
| DU145 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human DU145 cells after 48 hrs by MTT assay, IC50 = 6.072 μM. | 26301558 | ||
| A549 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human A549 cells after 48 hrs by MTT assay, IC50 = 7.244 μM. | 26301558 | ||
| HeLa | Antiproliferative assay | 48 hrs | Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay, IC50 = 8.317 μM. | 26301558 | ||
| MCF7 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay, IC50 = 19.39 μM. | 26363869 | ||
| A549 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human A549 cells after 48 hrs by MTT assay, IC50 = 22.28 μM. | 26363869 | ||
| PC3 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human PC3 cells after 48 hrs by MTT assay, IC50 = 22.63 μM. | 26363869 | ||
| HepG2 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay, IC50 = 46.83 μM. | 26363869 | ||
| HT-29 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human HT-29 cells assessed as growth inhibition after 48 hrs by WST-1 assay, IC50 = 15.83 μM. | 26413725 | ||
| PA1 | Anticancer assay | 48 hrs | Anticancer activity against human PA1 cells after 48 hrs by MTT assay, IC50 = 7.59 μM. | 26413726 | ||
| BT549 | Anticancer assay | 48 hrs | Anticancer activity against human BT549 cells after 48 hrs by MTT assay, IC50 = 19.82 μM. | 26413726 | ||
| DU145 | Anticancer assay | 48 hrs | Anticancer activity against human DU145 cells after 48 hrs by MTT assay, IC50 = 39.17 μM. | 26413726 | ||
| MDA-MB-231 | Anticancer assay | 48 hrs | Anticancer activity against human MDA-MB-231 cells after 48 hrs by MTT assay, IC50 = 45.43 μM. | 26413726 | ||
| SH-SY5Y | Antiproliferative assay | 72 hrs | Antiproliferative activity against human SH-SY5Y cells after 72 hrs by MTT-based Mosmann assay relative to control, GI50 = 1.5 μM. | 26539626 | ||
| Caco2 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human Caco2 cells after 72 hrs by MTT-based Mosmann assay relative to control, GI50 = 2.2 μM. | 26539626 | ||
| A549 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human A549 cells after 72 hrs by MTT assay, IC50 = 6.76 μM. | 26595184 | ||
| SGC7901 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human SGC7901 cells after 72 hrs by MTT assay, IC50 = 11.9 μM. | 26595184 | ||
| MDA-MB-435S | Antiproliferative assay | 72 hrs | Antiproliferative activity against human MDA-MB-435S cells after 72 hrs by MTT assay, IC50 = 15.19 μM. | 26595184 | ||
| L02 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human L02 cells after 72 hrs by MTT assay, IC50 = 25.9 μM. | 26595184 | ||
| PC3 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay, IC50 = 42.5 μM. | 26595184 | ||
| PANC1 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human PANC1 cells after 72 hrs by WST-8 assay, IC50 = 0.4 μM. | 26606140 | ||
| MDA-MB-231 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by WST-8 assay, IC50 = 1.1 μM. | 26606140 | ||
| HeLa | Antiproliferative assay | 72 hrs | Antiproliferative activity against human HeLa cells after 72 hrs by WST-8 assay, IC50 = 6.4 μM. | 26606140 | ||
| PSN1 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human PSN1 cells after 72 hrs by WST-8 assay, IC50 = 8.7 μM. | 26606140 | ||
| A549 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human A549 cells after 72 hrs by WST-8 assay, IC50 = 9 μM. | 26606140 | ||
| MCF7 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay, IC50 = 0.09 μM. | 26617970 | ||
| SW620 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human SW620 cells after 72 hrs by MTT assay, IC50 = 0.79 μM. | 26617970 | ||
| A549 | Cytotoxicity assay | Cytotoxicity against human A549 cells assessed as cell growth inhibition by MTT assay, IC50 = 1.1 μM. | 26629861 | |||
| Neuro2a | Cytotoxicity assay | Cytotoxicity against mouse Neuro2a cells assessed as cell growth inhibition by MTT assay, IC50 = 1.2 μM. | 26629861 | |||
| HeLa | Cytotoxicity assay | Cytotoxicity against human HeLa cells assessed as cell growth inhibition by MTT assay, IC50 = 1.5 μM. | 26629861 | |||
| COLO205 | Cytotoxicity assay | Cytotoxicity against human COLO205 cells assessed as cell growth inhibition by MTT assay, IC50 = 1.8 μM. | 26629861 | |||
| A549 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human A549 cells after 72 hrs by MTS assay, IC50 = 3.52 μM. | 26703795 | ||
| HCT116 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human HCT116 cells after 72 hrs by MTS assay, IC50 = 5.53 μM. | 26703795 | ||
| HT-29 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human HT-29 cells after 72 hrs by MTS assay, IC50 = 24.5 μM. | 26703795 | ||
| MCF7 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human MCF7 cells after 72 hrs by MTS assay, IC50 = 32.18 μM. | 26703795 | ||
| HeLa | Antiproliferative assay | 72 hrs | Antiproliferative activity against human HeLa cells after 72 hrs by MTS assay, IC50 = 43.71 μM. | 26703795 | ||
| SKOV3 | Cytotoxicity assay | 48 hrs | Cytotoxic activity against human SKOV3 cells assessed as inhibition of cell growth after 48 hrs by MTT assay, IC50 = 22.43 μM. | 26706349 | ||
| HCT116 | Cytotoxicity assay | 48 hrs | Cytotoxic activity against human HCT116 cells assessed as inhibition of cell growth after 48 hrs by MTT assay, IC50 = 24.58 μM. | 26706349 | ||
| Bel7404 | Cytotoxicity assay | 48 hrs | Cytotoxic activity against human Bel7404 cells assessed as inhibition of cell growth after 48 hrs by MTT assay, IC50 = 30.23 μM. | 26706349 | ||
| A549 | Cytotoxicity assay | 48 hrs | Cytotoxic activity against human A549 cells assessed as inhibition of cell growth after 48 hrs by MTT assay, IC50 = 31.33 μM. | 26706349 | ||
| NCI-H460 | Cytotoxicity assay | 48 hrs | Cytotoxic activity against human NCI-H460 cells assessed as inhibition of cell growth after 48 hrs by MTT assay, IC50 = 35.52 μM. | 26706349 | ||
| MDST8 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human MDST8 cells after 72 hrs by CCK8 assay, IC50 = 0.064 μM. | 26725029 | ||
| MCF7 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human MCF7 cells after 72 hrs by CCK8 assay, IC50 = 0.52 μM. | 26725029 | ||
| KM12 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human KM12 cells after 48 hrs by sulforhodamine B assay, IC50 = 14.8 μM. | 26727215 | ||
| HT-29 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human HT-29 cells after 48 hrs by sulforhodamine B assay, IC50 = 14.8 μM. | 26727215 | ||
| HCC2998 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human HCC2998 cells after 48 hrs by sulforhodamine B assay, IC50 = 14.8 μM. | 26727215 | ||
| COLO205 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human COLO205 cells after 48 hrs by sulforhodamine B assay, IC50 = 14.8 μM. | 26727215 | ||
| HCT116 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human HCT116 cells after 48 hrs by sulforhodamine B assay, IC50 = 14.8 μM. | 26727215 | ||
| HCT15 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human HCT15 cells after 48 hrs by sulforhodamine B assay, IC50 = 14.8 μM. | 26727215 | ||
| SW620 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human SW620 cells after 48 hrs by sulforhodamine B assay, IC50 = 14.8 μM. | 26727215 | ||
| MCF7 | Antiproliferative assay | 96 hrs | Antiproliferative activity against human MCF7 cells assessed as cellular DNA content after 96 hrs by CyQUANT NF fluorescence assay, IC50 = 0.9 μM. | 26731300 | ||
| PC3 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human PC3 cells assessed as cellular DNA content after 72 hrs by CyQUANT NF fluorescence assay, IC50 = 4.9 μM. | 26731300 | ||
| HT-29 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human HT-29 cells assessed as cellular DNA content after 72 hrs by CyQUANT NF fluorescence assay, IC50 = 5.3 μM. | 26731300 | ||
| T84 | Antiproliferative assay | 96 hrs | Antiproliferative activity against human T84 cells assessed as cellular DNA content after 96 hrs by CyQUANT NF fluorescence assay, IC50 = 6.2 μM. | 26731300 | ||
| PC3 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human PC3 cells assessed as growth inhibition after 72 hrs by MTT assay, IC50 = 1.44 μM. | 26735909 | ||
| A549 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human A549 cells assessed as growth inhibition after 72 hrs by MTT assay, IC50 = 3.47 μM. | 26735909 | ||
| U87MG | Cytotoxicity assay | 72 hrs | Cytotoxicity against human U87MG cells assessed as growth inhibition after 72 hrs by MTT assay, IC50 = 3.61 μM. | 26735909 | ||
| L929 | Antiproliferative assay | 48 hrs | Antiproliferative activity against mouse L929 cells after 48 hrs by CCK8 assay, IC50 = 2.98 μM. | 26786698 | ||
| SMMC7721 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human SMMC7721 cells after 48 hrs by CCK8 assay, IC50 = 5.62 μM. | 26786698 | ||
| A549 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human A549 cells after 48 hrs by CCK8 assay, IC50 = 8.13 μM. | 26786698 | ||
| HeLa | Antiproliferative assay | 48 hrs | Antiproliferative activity against human HeLa cells after 48 hrs by CCK8 assay, IC50 = 17.21 μM. | 26786698 | ||
| A549 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human A549 cells after 48 hrs by MTT assay, IC50 = 1.4 μM. | 26854375 | ||
| THP1 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human THP1 cells after 48 hrs by MTT assay, IC50 = 1.7 μM. | 26854375 | ||
| MCF7 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay, IC50 = 2 μM. | 26854375 | ||
| HCT116 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human HCT116 cells after 48 hrs by MTT assay, IC50 = 2.3 μM. | 26854375 | ||
| HCT8 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human HCT8 cells assessed as growth inhibition after 48 hrs by MTT assay, IC50 = 32.31 μM. | 26873416 | ||
| WI38 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human WI38 cells assessed as growth inhibition after 48 hrs by MTT assay, IC50 = 38.91 μM. | 26873416 | ||
| HepG2 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human HepG2 cells assessed as growth inhibition after 48 hrs by MTT assay, IC50 = 41.62 μM. | 26873416 | ||
| Hep3B | Cytotoxicity assay | 48 hrs | Cytotoxicity against human Hep3B cells after 48 hrs by MTT assay, IC50 = 10.53 μM. | 26883148 | ||
| A549 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human A549 cells after 48 hrs by MTT assay, IC50 = 34.27 μM. | 26883148 | ||
| MCF7 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay, IC50 = 42.78 μM. | 26883148 | ||
| Bcap37 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human Bcap37 cells after 48 hrs by MTT assay, IC50 = 47.09 μM. | 26883148 | ||
| HepG2 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay, IC50 = 49.72 μM. | 26883148 | ||
| MCF7 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human MCF7 cells assessed as cell viability after 72 hrs by MTT assay, IC50 = 26.14 μM. | 26922223 | ||
| HeLa | Antiproliferative assay | 72 hrs | Antiproliferative activity against human HeLa cells assessed as cell viability after 72 hrs by MTT assay, IC50 = 26.18 μM. | 26922223 | ||
| HL60 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human HL60 cells assessed as cell viability after 72 hrs by MTT assay, IC50 = 27.43 μM. | 26922223 | ||
| HCT116 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human HCT116 cells assessed as cell viability after 72 hrs by MTT assay, IC50 = 38.3 μM. | 26922223 | ||
| HepG2 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human HepG2 cells assessed as cell viability after 72 hrs by MTT assay, IC50 = 49.02 μM. | 26922223 | ||
| HT-29 | Anticancer assay | 72 hrs | Anticancer activity against human HT-29 cells assessed as inhibition of cell growth after 72 hrs by MTT assay, IC50 = 6.3 μM. | 26922233 | ||
| RKO | Anticancer assay | 72 hrs | Anticancer activity against human RKO cells assessed as inhibition of cell growth after 72 hrs by MTT assay, IC50 = 6.8 μM. | 26922233 | ||
| HT-29 | Anticancer assay | 48 hrs | Anticancer activity against human HT-29 cells assessed as inhibition of cell growth after 48 hrs by MTT assay, IC50 = 25 μM. | 26922233 | ||
| HCT116 | Anticancer assay | 72 hrs | Anticancer activity against human HCT116 cells assessed as inhibition of cell growth after 72 hrs by MTT assay, IC50 = 27.8 μM. | 26922233 | ||
| RKO | Anticancer assay | 48 hrs | Anticancer activity against human RKO cells assessed as inhibition of cell growth after 48 hrs by MTT assay, IC50 = 41.1 μM. | 26922233 | ||
| KB | Cytotoxicity assay | 72 hrs | Cytotoxicity against human KB cells after 72 hrs by SRB assay, IC50 = 4.84 μM. | 27073055 | ||
| HeLa | Cytotoxicity assay | 72 hrs | Cytotoxicity against human HeLa cells after 72 hrs by SRB assay, IC50 = 6.23 μM. | 27073055 | ||
| MCF7 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human MCF7cells after 72 hrs by SRB assay, IC50 = 6.53 μM. | 27073055 | ||
| HepG2 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human HepG2 cells after 72 hrs by SRB assay, IC50 = 6.6 μM. | 27073055 | ||
| HDF | Cytotoxicity assay | 72 hrs | Cytotoxicity against HDF cells after 72 hrs by SRB assay, IC50 = 7.02 μM. | 27073055 | ||
| 143B | Cytotoxicity assay | 72 hrs | Cytotoxicity against human 143B cells after 72 hrs by SRB assay, IC50 = 13.01 μM. | 27073055 | ||
| thymidine kinase deficient 143B | Cytotoxicity assay | 72 hrs | Cytotoxicity against human thymidine kinase deficient 143B cells after 72 hrs by SRB assay, IC50 = 16.31 μM. | 27073055 | ||
| U87MG | Cytotoxicity assay | 72 hrs | Cytotoxicity against human U87MG cells assessed as reduction in cell viability after 72 hrs by Z2 coulter counter method, IC50 = 18.25 μM. | 27081742 | ||
| PC3 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay, IC50 = 2.76 μM. | 27092413 | ||
| HT-29 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human HT-29 cells after 48 hrs by MTT assay, IC50 = 2.8 μM. | 27092413 | ||
| U87MG | Antiproliferative assay | 48 hrs | Antiproliferative activity against human U87MG cells after 48 hrs by MTT assay, IC50 = 3.65 μM. | 27092413 | ||
| A549 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human A549 cells after 48 hrs by MTT assay, IC50 = 3.98 μM. | 27092413 | ||
| HaCaT | Antiproliferative assay | 48 hrs | Antiproliferative activity against human HaCaT cells after 48 hrs by MTT assay, IC50 = 16.15 μM. | 27092413 | ||
| MGC803 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human MGC803 cells assessed as cell growth inhibition after 72 hrs by MTT assay, IC50 = 1.25 μM. | 27105028 | ||
| EC109 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human EC109 cells assessed as cell growth inhibition after 72 hrs by MTT assay, IC50 = 3.17 μM. | 27105028 | ||
| SH-SY5Y | Antiproliferative assay | 72 hrs | Antiproliferative activity against human SH-SY5Y cells assessed as cell growth inhibition after 72 hrs by MTT assay, IC50 = 3.26 μM. | 27105028 | ||
| U87 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human U87 cells assessed as cell growth inhibition after 72 hrs by MTT assay, IC50 = 5.61 μM. | 27105028 | ||
| MCF7 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human MCF7 cells assessed as cell growth inhibition after 72 hrs by MTT assay, IC50 = 7.61 μM. | 27105028 | ||
| MDA-MB-231 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay, IC50 = 24.6 μM. | 27128180 | ||
| MCF7 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay, IC50 = 30.41 μM. | 27128180 | ||
| A549 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human A549 cells after 48 hrs by MTT assay, IC50 = 35.41 μM. | 27128180 | ||
| HepG2 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay, IC50 = 46.83 μM. | 27128180 | ||
| MCF7 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay, IC50 = 13.5 μM. | 27133593 | ||
| Bcap37 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human Bcap37 cells after 48 hrs by MTT assay, IC50 = 15.47 μM. | 27133593 | ||
| Hep3B | Cytotoxicity assay | 48 hrs | Cytotoxicity against human Hep3B cells after 48 hrs by MTT assay, IC50 = 17.53 μM. | 27133593 | ||
| A549 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human A549 cells after 48 hrs by MTT assay, IC50 = 21.58 μM. | 27133593 | ||
| U251 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human U251 cells after 48 hrs by MTT assay, IC50 = 24.69 μM. | 27133593 | ||
| HepG2 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay, IC50 = 25.17 μM. | 27133593 | ||
| LNCAP | Cytotoxicity assay | 24 hrs | Cytotoxicity against human LNCAP cells assessed as growth inhibition after 24 hrs by sulforhodamine B assay, IC50 = 0.03 μM. | 27156770 | ||
| PC3 | Cytotoxicity assay | 24 hrs | Cytotoxicity against human PC3 cells assessed as growth inhibition after 24 hrs by sulforhodamine B assay, IC50 = 0.03 μM. | 27156770 | ||
| Bcap37 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human Bcap37 cells assessed as growth inhibition after 48 hrs by MTT assay, IC50 = 5.18 μM. | 27189676 | ||
| MCF7 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human MCF7 cells assessed as growth inhibition after 48 hrs by MTT assay, IC50 = 11.5 μM. | 27189676 | ||
| Hep3B | Cytotoxicity assay | 48 hrs | Cytotoxicity against human Hep3B cells assessed as growth inhibition after 48 hrs by MTT assay, IC50 = 22.99 μM. | 27189676 | ||
| HepG2 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human HepG2 cells assessed as growth inhibition after 48 hrs by MTT assay, IC50 = 40.34 μM. | 27189676 | ||
| A549 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human A549 cells assessed as growth inhibition after 48 hrs by MTT assay, IC50 = 44.05 μM. | 27189676 | ||
| PA1 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human PA1 cells assessed as decrease in cell viability after 48 hrs by MTT assay, IC50 = 8.51 μM. | 27210438 | ||
| U87MG | Cytotoxicity assay | 48 hrs | Cytotoxicity against human U87MG cells assessed as decrease in cell viability after 48 hrs by MTT assay, IC50 = 15.48 μM. | 27210438 | ||
| MCF7 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human MCF7 cells assessed as decrease in cell viability after 48 hrs by MTT assay, IC50 = 32.27 μM. | 27210438 | ||
| LNCAP | Cytotoxicity assay | 48 hrs | Cytotoxicity against human LNCAP cells assessed as decrease in cell viability after 48 hrs by MTT assay, IC50 = 47.18 μM. | 27210438 | ||
| MCF7 | Cytotoxicity assay | 24 hrs | Cytotoxicity against human MCF7 cells assessed as cell survivability after 24 hrs by crystal violet staining based microscopic analysis, IC50 = 11.1 μM. | 27234893 | ||
| HepG2 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human HepG2 cells measured after 48 hrs by MTT assay, IC50 = 46.83 μM. | 27287368 | ||
| A375-S2 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human A375-S2 cells assessed as inhibition of cell viability after 48 hrs by MTT reduction assay, IC50 = 1.91 μM. | 27295506 | ||
| ACHN | Antiproliferative assay | 48 hrs | Antiproliferative activity against human ACHN cells assessed as inhibition of cell viability after 48 hrs by MTT reduction assay, IC50 = 2.73 μM. | 27295506 | ||
| 22Rv1 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human 22Rv1 cells assessed as inhibition of cell viability after 48 hrs by MTT reduction assay, IC50 = 3.83 μM. | 27295506 | ||
| C4-2B | Antiproliferative assay | 48 hrs | Antiproliferative activity against human C4-2B cells assessed as inhibition of cell viability after 48 hrs by MTT reduction assay, IC50 = 5.64 μM. | 27295506 | ||
| A498 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human A498 cells assessed as inhibition of cell viability after 48 hrs by MTT reduction assay, IC50 = 8.83 μM. | 27295506 | ||
| A549 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human A549 cells assessed as reduction in cell viability after 72 hrs by WST-8 assay, IC50 = 2.8 μM. | 27311895 | ||
| MDA-MB-231 | Antiproliferative assay | 72 hrs | Antiproliferation activity against human MDA-MB-231 cells assessed as reduction in cell viability after 72 hrs by WST-8 assay, IC50 = 5.2 μM. | 27311895 | ||
| HeLa | Antiproliferative assay | 72 hrs | Antiproliferation activity against human HeLa cells assessed as reduction in cell viability after 72 hrs by WST-8 assay, IC50 = 5.8 μM. | 27311895 | ||
| MCF7 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 48 hrs by MTT assay, IC50 = 3 μM. | 27343853 | ||
| WI38 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human WI38 cells assessed as reduction in cell viability after 48 hrs by MTT assay, IC50 = 4 μM. | 27343853 | ||
| HepG2 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human HepG2 cells assessed as reduction in cell viability after 48 hrs by MTT assay, IC50 = 8 μM. | 27343853 | ||
| UO31 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human UO31 cells measured after 48 hrs by SRB assay, GI50 = 6.76083 μM. | 27391135 | ||
| U251 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human U251 cells measured after 48 hrs by SRB assay, GI50 = 42.6579 μM. | 27391135 | ||
| HCT116 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human HCT116 cells assessed as cell growth inhibition after 48 hrs by MTT assay, IC50 = 15.38 μM. | 27448774 | ||
| MDA-MB-231 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human MDA-MB-231 cells assessed as cell growth inhibition after 48 hrs by MTT assay, IC50 = 35.91 μM. | 27448774 | ||
| A549 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human A549 cells assessed as cell growth inhibition after 48 hrs by MTT assay, IC50 = 39.86 μM. | 27448774 | ||
| Caco2 | Growth inhibition assay | 72 hrs | Growth inhibition of human Caco2 cells measured after 72 hrs by MTT assay, GI50 = 3.3 μM. | 27504537 | ||
| MCF7 | Growth inhibition assay | 72 hrs | Growth inhibition of human MCF7 cells measured after 72 hrs by MTT assay, GI50 = 3.6 μM. | 27504537 | ||
| PC3 | Growth inhibition assay | 72 hrs | Growth inhibition of human PC3 cells measured after 72 hrs by MTT assay, GI50 = 4.1 μM. | 27504537 | ||
| A549 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human A549 cells measured after 72 hrs by MTT assay, IC50 = 6.8 μM. | 27537924 | ||
| SGC7901 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human SGC7901 cells measured after 72 hrs by MTT assay, IC50 = 11.9 μM. | 27537924 | ||
| MDA-MB-435S | Cytotoxicity assay | 72 hrs | Cytotoxicity against human MDA-MB-435S cells measured after 72 hrs by MTT assay, IC50 = 15.2 μM. | 27537924 | ||
| PC3 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human PC3 cells measured after 72 hrs by MTT assay, IC50 = 42.5 μM. | 27537924 | ||
| colon cancer cell | Growth inhibition assay | 48 hrs | Growth inhibition of human colon cancer cells after 48 hrs by SRB assay, GI50 = 8.4 μM. | 27554444 | ||
| leukemia cell | Growth inhibition assay | 48 hrs | Growth inhibition of human leukemia cells after 48 hrs by SRB assay, GI50 = 15.1 μM. | 27554444 | ||
| prostate cancer cell | Growth inhibition assay | 48 hrs | Growth inhibition of human prostate cancer cells after 48 hrs by SRB assay, GI50 = 22.7 μM. | 27554444 | ||
| renal cancer cell | Growth inhibition assay | 48 hrs | Growth inhibition of human renal cancer cells after 48 hrs by SRB assay, GI50 = 45.6 μM. | 27554444 | ||
| DU145 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human DU145 cells assessed as reduction in cell viability after 48 hrs by MTT assay, IC50 = 26.1 μM. | 27561718 | ||
| HeLa | Cytotoxicity assay | 48 hrs | Cytotoxicity against human HeLa cells assessed as reduction in cell viability after 48 hrs by MTT assay, IC50 = 28.2 μM. | 27561718 | ||
| IOSE-144 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human IOSE-144 cells assessed as reduction in cell viability after 48 hrs by MTT assay, IC50 = 36.1 μM. | 27561718 | ||
| HepG2 | Cytotoxicity assay | Cytotoxicity against human HepG2 cells assessed as cell growth inhibition by MTT assay, IC50 = 1.3 μM. | 27561719 | |||
| DU145 | Cytotoxicity assay | Cytotoxicity against human DU145 cells assessed as cell growth inhibition by MTT assay, IC50 = 1.6 μM. | 27561719 | |||
| MDA-MB-231 | Cytotoxicity assay | Cytotoxicity against human MDA-MB-231 cells assessed as cell growth inhibition by MTT assay, IC50 = 1.8 μM. | 27561719 | |||
| HeLa | Cytotoxicity assay | Cytotoxicity against human HeLa cells assessed as cell growth inhibition by MTT assay, IC50 = 1.9 μM. | 27561719 | |||
| SW780 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human SW780 cells assessed as growth inhibition after 72 hrs by CCK8 assay, IC50 = 6.99 μM. | 27597411 | ||
| MGC803 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human MGC803 cells assessed as growth inhibition after 72 hrs by CCK8 assay, IC50 = 10.64 μM. | 27597411 | ||
| HL-7702 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human HL-7702 cells assessed as growth inhibition after 72 hrs by CCK8 assay, IC50 = 12.85 μM. | 27597411 | ||
| MCF7 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human MCF7 cells assessed as growth inhibition after 72 hrs by CCK8 assay, IC50 = 13.19 μM. | 27597411 | ||
| GES-1 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human GES-1 cells assessed as growth inhibition after 72 hrs by CCK8 assay, IC50 = 13.75 μM. | 27597411 | ||
| TE1 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human TE1 cells assessed as growth inhibition after 72 hrs by CCK8 assay, IC50 = 17.32 μM. | 27597411 | ||
| A549 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human A549 cells assessed as cell growth inhibition after 48 hrs by MTT assay, IC50 = 30.47 μM. | 27614408 | ||
| MDA-MB-231 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human MDA-MB-231 cells assessed as cell growth inhibition after 48 hrs by MTT assay, IC50 = 35.98 μM. | 27614408 | ||
| DU145 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human DU145 cells assessed as cell growth inhibition after 48 hrs by MTT assay, IC50 = 40.58 μM. | 27614408 | ||
| PC3 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human PC3 cells assessed as cell growth inhibition after 48 hrs by MTT assay, IC50 = 45.32 μM. | 27614408 | ||
| MCF7 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human MCF7 cells assessed as growth inhibition measured after 48 hrs by MTT assay, GI50 = 4.5 μM. | 27688184 | ||
| HepG2 | Function assay | 48 hrs | Hepatotoxicity against human HepG2 cells assessed as growth inhibition measured after 48 hrs by MTT assay, GI50 = 7 μM. | 27688184 | ||
| U87 | Function assay | 48 hrs | Neurotoxicity against human U87 cells assessed as growth inhibition measured after 48 hrs by MTT assay, GI50 = 13 μM. | 27688184 | ||
| HCT116 | Growth inhibition assay | 72 hrs | Growth inhibition of human HCT116 cells after 72 hrs by MTS assay, IC50 = 2.5 μM. | 27704811 | ||
| HeLa | Cytotoxicity assay | Cytotoxicity against human HeLa cells assessed as cell growth inhibition by MTT assay, IC50 = 1.6 μM. | 27720296 | |||
| PC3 | Cytotoxicity assay | Cytotoxicity against human PC3 cells assessed as cell growth inhibition by MTT assay, IC50 = 1.8 μM. | 27720296 | |||
| HepG2 | Cytotoxicity assay | Cytotoxicity against human HepG2 cells assessed as cell growth inhibition by MTT assay, IC50 = 1.8 μM. | 27720296 | |||
| MDA-MB-231 | Cytotoxicity assay | Cytotoxicity against human MDA-MB-231 cells assessed as cell growth inhibition by MTT assay, IC50 = 1.9 μM. | 27720296 | |||
| L1210 | Antiproliferative assay | 48 hrs | Anti-proliferative activity against mouse L1210 cells measured after 48 hrs by coulter counter method, IC50 = 0.33 μM. | 27750154 | ||
| HeLa | Antiproliferative assay | 4 days | Anti-proliferative activity against human HeLa cells measured after 4 days by coulter counter method, IC50 = 0.54 μM. | 27750154 | ||
| CEM | Antiproliferative assay | 72 hrs | Anti-proliferative activity against human CEM cells measured after 72 hrs by coulter counter method, IC50 = 18 μM. | 27750154 | ||
| PC9 | Cytotoxicity assay | Cytotoxicity against human PC9 cells assessed as growth inhibition by MTT assay, IC50 = 1.99 μM. | 27769034 | |||
| MGC803 | Cytotoxicity assay | Cytotoxicity against human MGC803 cells assessed as growth inhibition by MTT assay, IC50 = 10.14 μM. | 27769034 | |||
| A549 | Cytotoxicity assay | Cytotoxicity against human A549 cells assessed as growth inhibition by MTT assay, IC50 = 13.95 μM. | 27769034 | |||
| EC109 | Cytotoxicity assay | Cytotoxicity against human EC109 cells assessed as growth inhibition by MTT assay, IC50 = 25.99 μM. | 27769034 | |||
| MGC803 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay, IC50 = 7.35 μM. | 27771599 | ||
| MCF7 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay, IC50 = 9.25 μM. | 27771599 | ||
| EC109 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human EC109 cells after 72 hrs by MTT assay, IC50 = 10.59 μM. | 27771599 | ||
| HUCCA | Cytotoxicity assay | 24 hrs | Cytotoxicity against HUCCA cells assessed as decrease in cell viability after 24 hrs by MTT assay, IC50 = 13.4 μM. | 27825763 | ||
| QBC939 | Cytotoxicity assay | 24 hrs | Cytotoxicity against human QBC939 cells assessed as decrease in cell viability after 24 hrs by MTT assay, IC50 = 16.1 μM. | 27825763 | ||
| SW620 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human SW620 cells after 72 hrs by MTT assay, IC50 = 0.08 μM. | 27875779 | ||
| CFPAC-1 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human CFPAC-1 cells after 72 hrs by MTT assay, IC50 = 0.14 μM. | 27875779 | ||
| WI38 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human WI38 cells after 72 hrs by MTT assay, IC50 = 0.94 μM. | 27875779 | ||
| A549 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human A549 cells after 72 hrs by MTT assay, IC50 = 2.8 μM. | 27875779 | ||
| HeLa | Antiproliferative assay | 72 hrs | Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay, IC50 = 8.81 μM. | 27875779 | ||
| HepG2 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay, IC50 = 8.9 μM. | 27875779 | ||
| Hep3B | Cytotoxicity assay | Cytotoxicity against human Hep3B cells assessed as cell growth inhibition by MTT assay, IC50 = 9.36 μM. | 27913179 | |||
| A549 | Cytotoxicity assay | Cytotoxicity against human A549 cells assessed as cell growth inhibition by MTT assay, IC50 = 16.63 μM. | 27913179 | |||
| WISH | Cytotoxicity assay | 24 hrs | Cytotoxicity against human WISH cells assessed as reduction in cell viability after 24 hrs by MTT assay, IC50 = 7.1 μM. | 27951487 | ||
| WI38 | Cytotoxicity assay | 24 hrs | Cytotoxicity against human WI38 cells assessed as reduction in cell viability after 24 hrs by MTT assay, IC50 = 9.3 μM. | 27951487 | ||
| A549 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human A549 cells after 72 hrs by MTT assay, IC50 = 1.16 μM. | 27987485 | ||
| MDA-MB-231 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by MTT assay, IC50 = 5 μM. | 27987485 | ||
| HepG2 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay, IC50 = 5 μM. | 27987485 | ||
| MCF7 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay, IC50 = 7.12 μM. | 27987485 | ||
| Hep3B | Cytotoxicity assay | 48 hrs | Cytotoxic activity against human Hep3B cells assessed as growth inhibition after 48 hrs by MTT assay, IC50 = 10.53 μM. | 27993516 | ||
| HepG2 | Cytotoxicity assay | 48 hrs | Cytotoxic activity against human HepG2 cells assessed as growth inhibition after 48 hrs by MTT assay, IC50 = 32.6 μM. | 27993516 | ||
| HepG2 | Growth inhibition assay | 24 hrs | Growth inhibition of human HepG2 cells after 24 hrs by MTT assay, IC50 = 32.87 μM. | 28011220 | ||
| PA1 | Growth inhibition assay | 24 hrs | Growth inhibition of human PA1 cells after 24 hrs by MTT assay, IC50 = 39.5 μM. | 28011220 | ||
| HCT15 | Growth inhibition assay | 24 hrs | Growth inhibition of human HCT15 cells after 24 hrs by MTT assay, IC50 = 45.01 μM. | 28011220 | ||
| PC3 | Cytotoxicity assay | 72 hrs | Cytotoxic activity against human PC3 cells assessed as reduction in cell viability after 72 hrs by SRB assay, IC50 = 15.31 μM. | 28011223 | ||
| SKOV3 | Cytotoxicity assay | 72 hrs | Cytotoxic activity against human SKOV3 cells assessed as reduction in cell viability after 72 hrs by SRB assay, IC50 = 23.11 μM. | 28011223 | ||
| A549 | Cytotoxicity assay | 72 hrs | Cytotoxic activity against human A549 cells assessed as reduction in cell viability after 72 hrs by SRB assay, IC50 = 32.15 μM. | 28011223 | ||
| HepG2 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human HepG2 cells assessed as decrease in cell proliferation after 48 hrs by MTT colorimetric assay, IC50 = 10.17 μM. | 28038327 | ||
| Hep3B | Cytotoxicity assay | 48 hrs | Cytotoxicity against human Hep3B cells assessed as decrease in cell proliferation after 48 hrs by MTT colorimetric assay, IC50 = 10.53 μM. | 28038327 | ||
| A549 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human A549 cells assessed as decrease in cell proliferation after 48 hrs by MTT colorimetric assay, IC50 = 34.27 μM. | 28038327 | ||
| MCF7 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human MCF7 cells assessed as decrease in cell proliferation after 48 hrs by MTT colorimetric assay, IC50 = 42.78 μM. | 28038327 | ||
| Bcap37 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human Bcap37 cells assessed as decrease in cell proliferation after 48 hrs by MTT colorimetric assay, IC50 = 47.1 μM. | 28038327 | ||
| U251 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human U251 cells assessed as decrease in cell proliferation after 48 hrs by MTT colorimetric assay, IC50 = 48.68 μM. | 28038327 | ||
| MGC803 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human MGC803 cells assessed as inhibition of cell viability after 48 hrs by MTT assay, IC50 = 7.21 μM. | 28038329 | ||
| EC109 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human EC109 cells assessed as inhibition of cell viability after 48 hrs by MTT assay, IC50 = 10.3 μM. | 28038329 | ||
| PC3 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human PC3 cells assessed as inhibition of cell viability after 48 hrs by MTT assay, IC50 = 29.31 μM. | 28038329 | ||
| A549 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human A549 cells after 48 hrs by MTT assay, IC50 = 10.5 μM. | 28073676 | ||
| MCF7 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay, IC50 = 19.2 μM. | 28073676 | ||
| HCT116 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay, IC50 = 29.2 μM. | 28073676 | ||
| BGC823 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human BGC823 cells after 48 hrs by MTT assay, IC50 = 34.8 μM. | 28073676 | ||
| IOSE-144 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human IOSE-144 cells after 48 hrs by MTT assay, IC50 = 38.1 μM. | 28073676 | ||
| MCF7 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay, IC50 = 26.14 μM. | 28110871 | ||
| HCT116 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay, IC50 = 38.3 μM. | 28110871 | ||
| PANC1 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human PANC1 cells after 48 hrs by MTT assay, IC50 = 47.83 μM. | 28110871 | ||
| HepG2 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay, IC50 = 49.02 μM. | 28110871 | ||
| BCG823 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human BCG823 cells assessed as reduction in cell viability after 48 hrs by MTT assay, IC50 = 10.1 μM. | 28117202 | ||
| A549 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human A549 cells assessed as reduction in cell viability after 48 hrs by MTT assay, IC50 = 16.1 μM. | 28117202 | ||
| HepG2 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human HepG2 cells assessed as reduction in cell viability after 48 hrs by MTT assay, IC50 = 17.2 μM. | 28117202 | ||
| EC9706 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human EC9706 cells after 48 hrs by MTT assay, IC50 = 23.26 μM. | 28119200 | ||
| ECA109 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human ECA109 cells after 48 hrs by MTT assay, IC50 = 30.25 μM. | 28119200 | ||
| K562 | Growth inhibition assay | 48 hrs | Growth inhibition of human K562 cells after 48 hrs by WST1 assay, IC50 = 38.58 μM. | 28126436 | ||
| KKU-M214 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human KKU-M214 cells assessed as reduction in cell viability after 72 hrs by SRB assay, IC50 = 3.76 μM. | 28140592 | ||
| HL60 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human HL60 cells after 48 hrs by MTS assay, IC50 = 1.62 μM. | 28152430 | ||
| NCI-H1299 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human NCI-H1299 cells after 48 hrs by MTS assay, IC50 = 8.91 μM. | 28152430 | ||
| MCF7 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay, IC50 = 1.75 μM. | 28165738 | ||
| Bel7402 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human Bel7402 cells after 72 hrs by MTT assay, IC50 = 2.25 μM. | 28165738 | ||
| MGC803 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay, IC50 = 3.12 μM. | 28165738 | ||
| K562 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human K562 cells after 72 hrs by MTT assay, IC50 = 3.54 μM. | 28165738 | ||
| HepG2 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human HepG2 cells assessed as growth inhibition after 48 hrs by MTT assay, IC50 = 10.53 μM. | 28174107 | ||
| Hep3B | Cytotoxicity assay | 48 hrs | Cytotoxicity against human Hep3B cells assessed as growth inhibition after 48 hrs by MTT assay, IC50 = 49.72 μM. | 28174107 | ||
| MCF7 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human MCF7 cells assessed as growth inhibition after 72 hrs by SRB assay, IC50 = 1.4 μM. | 28219046 | ||
| HCT116 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human HCT116 cells assessed as growth inhibition after 72 hrs by SRB assay, IC50 = 18.4 μM. | 28219046 | ||
| HuH7 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human HuH7 cells assessed as growth inhibition after 72 hrs by SRB assay, IC50 = 21 μM. | 28219046 | ||
| A549 | Cytotoxicity assay | 24 hrs | Cytotoxicity against human A549 cells after 24 hrs by MTT assay, IC50 = 1.2 μM. | 28254697 | ||
| HeLa | Cytotoxicity assay | 24 hrs | Cytotoxicity against human HeLa cells after 24 hrs by MTT assay, IC50 = 1.4 μM. | 28254697 | ||
| HepG2 | Cytotoxicity assay | 24 hrs | Cytotoxicity against human HepG2 cells after 24 hrs by MTT assay, IC50 = 1.4 μM. | 28254697 | ||
| COLO205 | Cytotoxicity assay | 24 hrs | Cytotoxicity against human COLO205 cells after 24 hrs by MTT assay, IC50 = 1.9 μM. | 28254697 | ||
| HepG2 | Cytotoxicity assay | Cytotoxicity against human HepG2 cells by MTT assay, IC50 = 2.1 μM. | 28262527 | |||
| Hep3B | Cytotoxicity assay | Cytotoxicity against human Hep3B cells by MTT assay, IC50 = 2.66 μM. | 28262527 | |||
| Bel7402 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human Bel7402 cells after 72 hrs by CCK-8 assay, IC50 = 5.94 μM. | 28301815 | ||
| LO2 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human LO2 cells after 72 hrs by CCK-8 assay, IC50 = 32.546 μM. | 28301815 | ||
| HCT116 | Cytotoxicity assay | Cytotoxicity in human HCT116 cells assessed as reduction in cell viability by MTT assay, IC50 = 41 μM. | 28334654 | |||
| MCF7 | Cytotoxicity assay | Cytotoxicity in human MCF7 cells assessed as reduction in cell viability by MTT assay, IC50 = 41.5 μM. | 28334654 | |||
| HeLa | Antiproliferative assay | 48 hrs | Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay, IC50 = 9.02 μM. | 28363444 | ||
| HepG2 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay, IC50 = 13.31 μM. | 28363444 | ||
| BGC823 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human BGC823 cells after 48 hrs by MTT assay, IC50 = 17.37 μM. | 28363444 | ||
| SW1116 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human SW1116 cells after 48 hrs by MTT assay, IC50 = 18.52 μM. | 28363444 | ||
| Hep3B | Cytotoxicity assay | Cytotoxicity against human Hep3B cells by MTT assay, IC50 = 11.9 μM. | 28371676 | |||
| MCF7 | Cytotoxicity assay | Cytotoxicity against human MCF7 cells by MTT assay, IC50 = 30 μM. | 28371676 | |||
| HepG2 | Cytotoxicity assay | Cytotoxicity against human HepG2 cells by MTT assay, IC50 = 32.6 μM. | 28371676 | |||
| A549 | Cytotoxicity assay | Cytotoxicity against human A549 cells by MTT assay, IC50 = 38.2 μM. | 28371676 | |||
| MCF7 | Antiproliferative assay | 48 to 72 hrs | Antiproliferative activity against human MCF7 cells incubated for 48 to 72 hrs by MTT assay, IC50 = 7.67 μM. | 28395218 | ||
| A549 | Antiproliferative assay | 48 to 72 hrs | Antiproliferative activity against human A549 cells incubated for 48 to 72 hrs by MTT assay, IC50 = 10.65 μM. | 28395218 | ||
| SGC7901 | Antiproliferative assay | 48 to 72 hrs | Antiproliferative activity against human SGC7901 cells incubated for 48 to 72 hrs by MTT assay, IC50 = 13.25 μM. | 28395218 | ||
| HepG2 | Antiproliferative assay | 48 to 72 hrs | Antiproliferative activity against human HepG2 cells incubated for 48 to 72 hrs by MTT assay, IC50 = 17.44 μM. | 28395218 | ||
| PC3 | Antiproliferative assay | 48 to 72 hrs | Antiproliferative activity against human PC3 cells incubated for 48 to 72 hrs by MTT assay, IC50 = 38.61 μM. | 28395218 | ||
| MCF7 | Growth inhibition assay | 48 hrs | Growth inhibition of human MCF7 cells after 48 hrs by SRB assay, GI50 = 1.67 μM. | 28400235 | ||
| A549 | Growth inhibition assay | 48 hrs | Growth inhibition of human A549 cells after 48 hrs by SRB assay, GI50 = 2.09 μM. | 28400235 | ||
| DU145 | Growth inhibition assay | 48 hrs | Growth inhibition of human DU145 cells after 48 hrs by SRB assay, GI50 = 5.82 μM. | 28400235 | ||
| T47D | Antiproliferative assay | 48 hrs | Antiproliferative activity against human T47D cells after 48 hrs by MTT assay, IC50 = 12.1 μM. | 28400238 | ||
| A549 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human A549 cells after 48 hrs by MTT assay, IC50 = 15.1 μM. | 28400238 | ||
| HepG2 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay, IC50 = 20.1 μM. | 28400238 | ||
| HCT116 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay, IC50 = 26.2 μM. | 28400238 | ||
| MCF7 | Cytotoxicity assay | Cytotoxicity against human MCF7 cells, IC50 = 7.9 μM. | 28431341 | |||
| HepG2 | Cytotoxicity assay | Cytotoxicity against human HepG2 cells, IC50 = 8.1 μM. | 28431341 | |||
| HCT116 | Cytotoxicity assay | Cytotoxicity against human HCT116 cells, IC50 = 9.9 μM. | 28431341 | |||
| PC3 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human PC3 cells after 48 hrs by MTT assay, IC50 = 1.2 μM. | 28431881 | ||
| A549 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human A549 cells after 48 hrs by MTT assay, IC50 = 1.6 μM. | 28431881 | ||
| HeLa | Cytotoxicity assay | 48 hrs | Cytotoxicity against human HeLa cells after 48 hrs by MTT assay, IC50 = 1.86 μM. | 28431881 | ||
| DU145 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human DU145 cells after 48 hrs by MTT assay, IC50 = 2.18 μM. | 28431881 | ||
| MDA-MB-231 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human MDA-MB-231 cells after 48 hrs by MTT assay, IC50 = 4.33 μM. | 28431881 | ||
| HGC27 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human HGC27 cells after 48 hrs by MTT assay, IC50 = 14.72 μM. | 28431881 | ||
| MGC803 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay, IC50 = 6.56 μM. | 28456031 | ||
| HGC27 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human HGC27 cells after 72 hrs by MTT assay, IC50 = 8.22 μM. | 28456031 | ||
| NCI-H1650 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human NCI-H1650 cells after 72 hrs by MTT assay, IC50 = 12.52 μM. | 28456031 | ||
| HCT116 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay, IC50 = 4.16 μM. | 28458133 | ||
| PC3 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay, IC50 = 24.33 μM. | 28458133 | ||
| MCF7 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay, IC50 = 28.73 μM. | 28458133 | ||
| HepG2 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay, IC50 = 29.07 μM. | 28458133 | ||
| Caco2 | Cytotoxicity assay | 24 hrs | Cytotoxicity against human Caco2 cells assessed as cell viability after 24 hrs by MTT assay, IC50 = 31 μM. | 28463785 | ||
| HeLa | Cytotoxicity assay | 72 hrs | Cytotoxicity against human HeLa cells assessed as reduction in cell viability after 72 hrs by WST8 assay, IC50 = 13.9 μM. | 28488862 | ||
| HT-29 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human HT-29 cells after 72 hrs by MTT assay, IC50 = 4.9 μM. | 28494251 | ||
| PC3 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay, IC50 = 24.3 μM. | 28494251 | ||
| HepG2 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay, IC50 = 29.1 μM. | 28494251 | ||
| SW620 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human SW620 cells after 72 hrs by MTT assay, IC50 = 0.08 μM. | 28525845 | ||
| CFPAC-1 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human CFPAC-1 cells after 72 hrs by MTT assay, IC50 = 0.14 μM. | 28525845 | ||
| WI38 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human WI38 cells after 72 hrs by MTT assay, IC50 = 0.94 μM. | 28525845 | ||
| HeLa | Antiproliferative assay | 72 hrs | Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay, IC50 = 8.81 μM. | 28525845 | ||
| HepG2 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay, IC50 = 8.9 μM. | 28525845 | ||
| HCT116 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human HCT116 cells assessed as reduction in cell viability after 48 hrs by MTT assay, IC50 = 41.9 μM. | 28532669 | ||
| A549 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human A549 cells assessed as decrease in cell viability after 72 hrs by WST8 assay, IC50 = 4.7 μM. | 28558970 | ||
| HeLa | Cytotoxicity assay | 72 hrs | Cytotoxicity against human HeLa cells assessed as decrease in cell viability after 72 hrs by WST8 assay, IC50 = 5.3 μM. | 28558970 | ||
| MCF7 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human MCF7 cells assessed as decrease in cell viability after 72 hrs by WST8 assay, IC50 = 5.6 μM. | 28558970 | ||
| WI38 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human WI38 cells assessed as decrease in cell viability after 72 hrs by WST8 assay, IC50 = 6.8 μM. | 28558970 | ||
| HCT116 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human HCT116 cells assessed as decrease in cell viability after 48 hrs by MTT assay, IC50 = 4 μM. | 28623814 | ||
| MCF7 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human MCF7 cells assessed as decrease in cell viability after 48 hrs by MTT assay, IC50 = 4.3 μM. | 28623814 | ||
| HepG2 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human HepG2 cells assessed as decrease in cell viability after 48 hrs by MTT assay, IC50 = 5.3 μM. | 28623814 | ||
| W138 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human W138 cells assessed as decrease in cell viability after 48 hrs by MTT assay, IC50 = 5.73 μM. | 28623814 | ||
| P388 | Cytotoxicity assay | 72 hrs | Cytotoxicity against mouse P388 cells incubated for 72 hrs by alamar blue assay, IC50 = 5.8 μM. | 28648460 | ||
| MOLT4 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human MOLT4 cells incubated for 72 hrs by alamar blue assay, IC50 = 6.2 μM. | 28648460 | ||
| HT-29 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human HT-29 cells incubated for 72 hrs by alamar blue assay, IC50 = 7.2 μM. | 28648460 | ||
| K562 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human K562 cells incubated for 72 hrs by alamar blue assay, IC50 = 30.5 μM. | 28648460 | ||
| MCF7 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay, IC50 = 3.18 μM. | 28666860 | ||
| LNCAP | Antiproliferative assay | 48 hrs | Antiproliferative activity against human LNCAP cells after 48 hrs by MTT assay, IC50 = 5.21 μM. | 28666860 | ||
| PC3 | Cytotoxicity assay | Cytotoxic activity against human PC3 cells, IC50 = 1.6 μM. | 28697923 | |||
| HL60 | Cytotoxicity assay | Cytotoxic activity against human HL60 cells, IC50 = 2.8 μM. | 28697923 | |||
| HCT116 | Cytotoxicity assay | Cytotoxic activity against human HCT116 cells, IC50 = 17.01 μM. | 28697923 | |||
| HCT116 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human HCT116 cells after 48 hrs by sulforhodamine B assay, GI50 = 5.47 μM. | 28716495 | ||
| CRL1790 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human CRL1790 cells assessed as reduction in cell viability after 48 hrs by sulforhodamine B assay, GI50 = 10.3 μM. | 28716495 | ||
| SW1573 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human SW1573 cells after 48 hrs by SRB assay, GI50 = 4.3 μM. | 28728108 | ||
| HBL100 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human HBL100 cells after 48 hrs by SRB assay, GI50 = 5.5 μM. | 28728108 | ||
| hTERT-BJ | Antiproliferative assay | 48 hrs | Antiproliferative activity against human hTERT-BJ cells after 48 hrs by SRB assay, GI50 = 5.5 μM. | 28728108 | ||
| HeLa | Antiproliferative assay | 48 hrs | Antiproliferative activity against human HeLa cells after 48 hrs by SRB assay, GI50 = 15 μM. | 28728108 | ||
| T47D | Antiproliferative assay | 48 hrs | Antiproliferative activity against human T47D cells after 48 hrs by SRB assay, GI50 = 47 μM. | 28728108 | ||
| WiDr | Antiproliferative assay | 48 hrs | Antiproliferative activity against human WiDr cells after 48 hrs by SRB assay, GI50 = 49 μM. | 28728108 | ||
| A549 | Cytotoxicity assay | 48 hrs | Cytotoxicity in human A549 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay, IC50 = 34.47 μM. | 28754470 | ||
| T24 | Cytotoxicity assay | 48 hrs | Cytotoxicity in human T24 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay, IC50 = 40.14 μM. | 28754470 | ||
| SPCA2 | Cytotoxicity assay | 48 hrs | Cytotoxicity in human SPCA2 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay, IC50 = 44.34 μM. | 28754470 | ||
| HepG2 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay, IC50 = 28.8 μM. | 28756264 | ||
| SKOV3 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human SKOV3 cells after 48 hrs by MTT assay, IC50 = 32.5 μM. | 28756264 | ||
| NCI-H460 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human NCI-H460 cells after 48 hrs by MTT assay, IC50 = 36 μM. | 28756264 | ||
| MCF7 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay, IC50 = 38.5 μM. | 28756264 | ||
| HL-7702 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human HL-7702 cells after 48 hrs by MTT assay, IC50 = 46 μM. | 28756264 | ||
| EC109 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human EC109 cells after 72 hrs by MTT assay, IC50 = 5.01 μM. | 28759876 | ||
| MGC803 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay, IC50 = 6.89 μM. | 28759876 | ||
| MCF7 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay, IC50 = 7.21 μM. | 28759876 | ||
| GES-1 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human GES-1 cells assessed as reduction in cell viability after 72 hrs by MTT assay, IC50 = 8.59 μM. | 28759876 | ||
| HGC27 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human HGC27 cells after 72 hrs by MTT assay, IC50 = 11.02 μM. | 28759876 | ||
| MCF7 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 72 hrs by MTT assay, IC50 = 5.2 μM. | 28759877 | ||
| PC3 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human PC3 cells assessed as reduction in cell viability after 72 hrs by MTT assay, IC50 = 13.7 μM. | 28759877 | ||
| SKOV3 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human SKOV3 cells assessed as reduction in cell viability after 72 hrs by MTT assay, IC50 = 20.8 μM. | 28759877 | ||
| MDA-MB-231 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability after 72 hrs by MTT assay, IC50 = 24.5 μM. | 28759877 | ||
| MGC803 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human MGC803 cells after 48 hrs by MTT assay, IC50 = 9.79 μM. | 28763643 | ||
| PC3 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay, IC50 = 12.87 μM. | 28763643 | ||
| SH-SY5Y | Antiproliferative assay | 48 hrs | Antiproliferative activity against human SH-SY5Y cells after 48 hrs by MTT assay, GI50 = 12 μM. | 28763647 | ||
| K562 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human K562 cells after 48 hrs by MTT assay, GI50 = 19 μM. | 28763647 | ||
| AGS | Antiproliferative assay | 48 hrs | Antiproliferative activity against human AGS cells after 48 hrs by MTT assay, GI50 = 25 μM. | 28763647 | ||
| HeLa | Cytotoxicity assay | 24 hrs | Cytotoxicity against human HeLa cells assessed as reduction in cell viability after 24 hrs by MTT assay, IC50 = 2.9 μM. | 28838694 | ||
| EC109 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human EC109 cells after 48 hrs by MTT assay, IC50 = 6.21 μM. | 28838695 | ||
| MGC803 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human MGC803 cells after 48 hrs by MTT assay, IC50 = 7.52 μM. | 28838695 | ||
| MKN45 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human MKN45 cells after 48 hrs by MTT assay, IC50 = 8.89 μM. | 28838695 | ||
| NCI-H1650 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human NCI-H1650 cells after 48 hrs by MTT assay, IC50 = 14.25 μM. | 28838695 | ||
| EC109 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human EC109 cells after 48 hrs by MTT assay, IC50 = 6.21 μM. | 28863355 | ||
| MGC803 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human MGC803 cells after 48 hrs by MTT assay, IC50 = 7.52 μM. | 28863355 | ||
| MKN45 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human MKN45 cells after 48 hrs by MTT assay, IC50 = 8.89 μM. | 28863355 | ||
| GES-1 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human GES-1 cells after 48 hrs by MTT assay, IC50 = 9.02 μM. | 28863355 | ||
| A549 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human A549 cells after 48 hrs by MTT assay, IC50 = 12.92 μM. | 28863355 | ||
| NCI-H1650 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human NCI-H1650 cells after 48 hrs by MTT assay, IC50 = 14.25 μM. | 28863355 | ||
| A549 | Growth inhibition assay | 48 hrs | Growth inhibition of human A549 cells after 48 hrs by SRB assay, GI50 = 4.2 μM. | 28898082 | ||
| PC3 | Growth inhibition assay | 48 hrs | Growth inhibition of human PC3 cells after 48 hrs by SRB assay, GI50 = 11.7 μM. | 28898082 | ||
| PC3 | Cytotoxicity assay | 48 hrs | Cytotoxicity in human PC3 cells incubated for 48 hrs by MTT assay, IC50 = 1.2 μM. | 28923381 | ||
| DU145 | Cytotoxicity assay | 48 hrs | Cytotoxicity in human DU145 cells incubated for 48 hrs by MTT assay, IC50 = 2.18 μM. | 28923381 | ||
| HCT116 | Cytotoxicity assay | 48 hrs | Cytotoxicity in human HCT116 cells incubated for 48 hrs by MTT assay, IC50 = 8.62 μM. | 28923381 | ||
| HT-29 | Antitumor assay | 48 hrs | Antitumor activity against human HT-29 cells assessed as inhibition of cell viability incubated for 48 hrs by MTT assay, IC50 = 4.6 μM. | 28926764 | ||
| MCF7 | Antitumor assay | 48 hrs | Antitumor activity against human MCF7 cells assessed as inhibition of cell viability incubated for 48 hrs by MTT assay, IC50 = 5.7 μM. | 28926764 | ||
| WI38 | Cytotoxicity assay | 48 hrs | Cytotoxicity in human WI38 cells assessed as inhibition of cell viability incubated for 48 hrs by MTT assay, IC50 = 5.7 μM. | 28926764 | ||
| HepG2 | Antitumor assay | 48 hrs | Antitumor activity against human HepG2 cells assessed as inhibition of cell viability incubated for 48 hrs by MTT assay, IC50 = 6.9 μM. | 28926764 | ||
| L02 | Antiproliferative assay | 48 hrs | Anti-proliferative activity against human L02 cells after 48 hrs by MTT assay, IC50 = 19.1 μM. | 28947149 | ||
| AGS | Antiproliferative assay | 48 hrs | Anti-proliferative activity against human AGS cells after 48 hrs by MTT assay, IC50 = 29.6 μM. | 28947149 | ||
| B16 | Cytotoxicity assay | 72 hrs | Cytotoxicity in mouse B16 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay, IC50 = 1.19 μM. | 28987604 | ||
| A549 | Cytotoxicity assay | 72 hrs | Cytotoxicity in human A549 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay, IC50 = 8.9 μM. | 28987604 | ||
| HepG2 | Cytotoxicity assay | 72 hrs | Cytotoxicity in human HepG2 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay, IC50 = 10.4 μM. | 28987604 | ||
| MCF7 | Cytotoxicity assay | 72 hrs | Cytotoxicity in human MCF7 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay, IC50 = 14.7 μM. | 28987604 | ||
| HL60 | Antiproliferative assay | 24 hrs | Antiproliferative activity against human HL60 cells treated for 24 hrs measured after 72 hrs by MTT assay, IC50 = 3.69 μM. | 29037951 | ||
| THP1 | Antiproliferative assay | 24 hrs | Antiproliferative activity against human THP1 cells treated for 24 hrs measured after 72 hrs by MTT assay, IC50 = 4.87 μM. | 29037951 | ||
| PC3 | Antiproliferative assay | 24 hrs | Antiproliferative activity against human PC3 cells treated for 24 hrs measured after 72 hrs by MTT assay, IC50 = 23.94 μM. | 29037951 | ||
| HepG2 | Antiproliferative assay | 24 hrs | Antiproliferative activity against human HepG2 cells treated for 24 hrs measured after 72 hrs by MTT assay, IC50 = 30.48 μM. | 29037951 | ||
| SH-SY5Y | Antiproliferative assay | 48 hrs | Antiproliferative activity against human SH-SY5Y cells after 48 hrs by MTT assay, GI50 = 11.9 μM. | 29040954 | ||
| K562 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human K562 cells after 48 hrs by MTT assay, GI50 = 18.5 μM. | 29040954 | ||
| AGS | Antiproliferative assay | 48 hrs | Antiproliferative activity against human AGS cells after 48 hrs by MTT assay, GI50 = 24.6 μM. | 29040954 | ||
| EC109 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human EC109 cells assessed as decrease in cell viability after 48 hrs by MTT assay, IC50 = 6.21 μM. | 29113745 | ||
| MGC803 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human MGC803 cells assessed as decrease in cell viability after 48 hrs by MTT assay, IC50 = 7.52 μM. | 29113745 | ||
| MKN45 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human MKN45 cells assessed as decrease in cell viability after 48 hrs by MTT assay, IC50 = 8.89 μM. | 29113745 | ||
| NCI-H1650 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human NCI-H1650 cells assessed as decrease in cell viability after 48 hrs by MTT assay, IC50 = 14.25 μM. | 29113745 | ||
| HL60 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human HL60 cells after 72 hrs by tryphan blue staining based hematocytometric method, IC50 = 2.8 μM. | 29131616 | ||
| PC3 | Antiproliferative assay | Antiproliferative activity against human PC3 cells by MTT assay, IC50 = 22.02 μM. | 29131616 | |||
| EAC | Cytotoxicity assay | 48 hrs | Cytotoxicity against mouse EAC cells assessed as reduction in cell viability after 48 hrs by MTT assay, IC50 = 9.2 μM. | 29133037 | ||
| EAC | Cytotoxicity assay | 48 hrs | Cytotoxicity against mouse EAC cells assessed as reduction in cell viability after 48 hrs by trypan blue exclusion assay, IC50 = 9.6 μM. | 29133037 | ||
| MCF7 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 48 hrs by MTT assay, IC50 = 10.2 μM. | 29133037 | ||
| MCF7 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 48 hrs by trypan blue exclusion assay, IC50 = 10.6 μM. | 29133037 | ||
| DLA | Cytotoxicity assay | 48 hrs | Cytotoxicity against mouse DLA cells assessed as reduction in cell viability after 48 hrs by trypan blue exclusion assay, IC50 = 10.6 μM. | 29133037 | ||
| DLA | Cytotoxicity assay | 48 hrs | Cytotoxicity against mouse DLA cells assessed as reduction in cell viability after 48 hrs by MTT assay, IC50 = 10.8 μM. | 29133037 | ||
| A549 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human A549 cells assessed as reduction in cell viability after 48 hrs by trypan blue exclusion assay, IC50 = 11.2 μM. | 29133037 | ||
| A549 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human A549 cells assessed as reduction in cell viability after 48 hrs by MTT assay, IC50 = 11.4 μM. | 29133037 | ||
| MDA-MB-468 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human MDA-MB-468 cells assessed as reduction in cell viability after 48 hrs by trypan blue exclusion assay, IC50 = 44.6 μM. | 29133037 | ||
| MDA-MB-468 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human MDA-MB-468 cells assessed as reduction in cell viability after 48 hrs by MTT assay, IC50 = 44.9 μM. | 29133037 | ||
| SW620 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human SW620 cells after 72 hrs by MTT assay, IC50 = 0.08 μM. | 29133046 | ||
| CFPAC-1 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human CFPAC-1 cells after 72 hrs by MTT assay, IC50 = 0.14 μM. | 29133046 | ||
| WI38 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human WI38 cells after 72 hrs by MTT assay, IC50 = 0.94 μM. | 29133046 | ||
| A549 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human A549 cells after 72 hrs by MTT assay, IC50 = 2.8 μM. | 29133046 | ||
| HeLa | Antiproliferative assay | 72 hrs | Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay, IC50 = 8.81 μM. | 29133046 | ||
| K562 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human K562 cells assessed as reduction in cell viability after 48 hrs by MTT assay, IC50 = 9.49 μM. | 29133049 | ||
| WM9 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human WM9 cells assessed as reduction in cell viability after 48 hrs by MTT assay, IC50 = 15.8 μM. | 29133049 | ||
| HEL | Cytotoxicity assay | 48 hrs | Cytotoxicity against human HEL cells assessed as reduction in cell viability after 48 hrs by MTT assay, IC50 = 15.98 μM. | 29133049 | ||
| MDA-MB-231 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability after 48 hrs by MTT assay, IC50 = 17.74 μM. | 29133049 | ||
| PC3 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human PC3 cells assessed as reduction in cell viability after 48 hrs by MTT assay, IC50 = 19.87 μM. | 29133049 | ||
| PC3 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay, IC50 = 4.75 μM. | 29133051 | ||
| A549 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human A549 cells after 48 hrs by MTT assay, IC50 = 8.48 μM. | 29133051 | ||
| SGC7901 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human SGC7901 cells after 48 hrs by MTT assay, IC50 = 10.98 μM. | 29133051 | ||
| MGC803 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human MGC803 cells after 48 hrs by MTT assay, IC50 = 14.15 μM. | 29133051 | ||
| HT-29 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human HT-29 cells assessed as cell growth inhibition after 48 hrs by MTT assay, IC50 = 8.3 μM. | 29133061 | ||
| HCT15 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human HCT15 cells after 48 hrs by MTT assay, IC50 = 7.53 μM. | 29174813 | ||
| Bel7402 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human Bel7402 cells after 48 hrs by MTT assay, IC50 = 20.93 μM. | 29174813 | ||
| MCF7 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay, IC50 = 28.97 μM. | 29174813 | ||
| U937 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human U937 cells in presence of ubenimex after 48 hrs by MTT assay, IC50 = 9.56 μM. | 29202398 | ||
| HepG2 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human HepG2 cells in presence of ubenimex after 48 hrs by MTT assay, IC50 = 14.52 μM. | 29202398 | ||
| A549 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human A549 cells in presence of ubenimex after 48 hrs by MTT assay, IC50 = 15.93 μM. | 29202398 | ||
| A549 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human A549 cells after 48 hrs by MTT assay, IC50 = 17.02 μM. | 29202398 | ||
| H7402 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human H7402 cells in presence of ubenimex after 48 hrs by MTT assay, IC50 = 17.58 μM. | 29202398 | ||
| HepG2 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay, IC50 = 18.35 μM. | 29202398 | ||
| H7402 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human H7402 cells after 48 hrs by MTT assay, IC50 = 21.87 μM. | 29202398 | ||
| PLC/PRF/5 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human PLC/PRF/5 cells in presence of ubenimex after 48 hrs by MTT assay, IC50 = 22.81 μM. | 29202398 | ||
| U937 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human U937 cells after 48 hrs by MTT assay, IC50 = 28.76 μM. | 29202398 | ||
| PLC/PRF/5 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human PLC/PRF/5 cells after 48 hrs by MTT assay, IC50 = 35.66 μM. | 29202398 | ||
| ES2 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human ES2 cells in presence of ubenimex after 48 hrs by MTT assay, IC50 = 37.05 μM. | 29202398 | ||
| U266 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human U266 cells in presence of ubenimex after 48 hrs by MTT assay, IC50 = 43.48 μM. | 29202398 | ||
| HCT116 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human HCT116 cells in presence of ubenimex after 48 hrs by MTT assay, IC50 = 44.06 μM. | 29202398 | ||
| MCF7 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay, IC50 = 2.35 μM. | 29223098 | ||
| HCT116 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay, IC50 = 8.638 μM. | 29223717 | ||
| 143B | Antiproliferative assay | 48 hrs | Antiproliferative activity against human 143B cells after 48 hrs by MTT assay, IC50 = 25.216 μM. | 29223717 | ||
| MCF7 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay, IC50 = 32.626 μM. | 29223717 | ||
| HCT116 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay, IC50 = 29.5 μM. | 29232583 | ||
| SGC7901 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human SGC7901 cells after 72 hrs by MTT assay, IC50 = 34.4 μM. | 29232583 | ||
| SMMC7721 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human SMMC7721 cells after 72 hrs by MTT assay, IC50 = 37.8 μM. | 29232583 | ||
| HuH7 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human HuH7 cells after 72 hrs by MTT assay, IC50 = 5.63 μM. | 29316536 | ||
| HCT116 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay, IC50 = 11.29 μM. | 29316536 | ||
| MGC803 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay, IC50 = 25.54 μM. | 29316536 | ||
| MGC803 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay, IC50 = 7.86 μM. | 29407946 | ||
| NCI-H1650 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human NCI-H1650 cells after 72 hrs by MTT assay, IC50 = 14.63 μM. | 29407946 | ||
| PC3 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay, IC50 = 27.61 μM. | 29407946 | ||
| HL60 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human HL60 cells after 72 hrs by MTT assay, IC50 = 2.37 μM. | 29407983 | ||
| Bel7402 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human Bel7402 cells after 72 hrs by MTT assay, IC50 = 18.49 μM. | 29407983 | ||
| PC3 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay, IC50 = 23.86 μM. | 29407983 | ||
| EC9706 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human EC9706 cells after 72 hrs by MTT assay, IC50 = 5.13 μM. | 29475156 | ||
| EC109 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human EC109 cells after 72 hrs by MTT assay, IC50 = 6.02 μM. | 29475156 | ||
| PC3 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay, IC50 = 6.27 μM. | 29475156 | ||
| MGC803 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay, IC50 = 9.24 μM. | 29475156 | ||
| SMMC7721 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human SMMC7721 cells after 72 hrs by MTT assay, IC50 = 13.7 μM. | 29475156 | ||
| MCF7 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay, IC50 = 18.75 μM. | 29475156 | ||
| MCF7 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay, IC50 = 15.78 μM. | 29486954 | ||
| HCT116 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay, IC50 = 17.25 μM. | 29486954 | ||
| A549 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human A549 cells after 48 hrs by MTT assay, IC50 = 19.52 μM. | 29486954 | ||
| HepG2 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay, IC50 = 23.6 μM. | 29486954 | ||
| HeLa | Cytotoxicity assay | Cytotoxicity against human HeLa cells assessed as decrease in cell viability by MTT assay, IC50 = 28 μM. | 29489361 | |||
| A549 | Cytotoxicity assay | Cytotoxicity against human A549 cells assessed as decrease in cell viability by MTT assay, IC50 = 36.8 μM. | 29489361 | |||
| QSG7701 | Antiproliferative assay | 24 hrs | Antiproliferative activity against human QSG7701 cells after 24 hrs by CCK-8 assay, IC50 = 6.92 μM. | 29499490 | ||
| SMMC7721 | Antiproliferative assay | 24 hrs | Antiproliferative activity against human SMMC7721 cells after 24 hrs by CCK-8 assay, IC50 = 12.47 μM. | 29499490 | ||
| QGY7703 | Antiproliferative assay | 24 hrs | Antiproliferative activity against human QGY7703 cells after 24 hrs by CCK-8 assay, IC50 = 14.2 μM. | 29499490 | ||
| HepG2 | Antiproliferative assay | 24 hrs | Antiproliferative activity against human HepG2 cells after 24 hrs by CCK-8 assay, IC50 = 15.74 μM. | 29499490 | ||
| HL60 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human HL60 cells after 72 hrs by MTT assay, IC50 = 2.37 μM. | 29524728 | ||
| Bel7402 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human Bel7402 cells after 72 hrs by MTT assay, IC50 = 18.49 μM. | 29524728 | ||
| PC3 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay, IC50 = 23.86 μM. | 29524728 | ||
| MGC803 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay, IC50 = 8.66 μM. | 29635165 | ||
| PC3 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay, IC50 = 12.33 μM. | 29635165 | ||
| GES-1 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human GES-1 cells after 72 hrs by MTT assay, IC50 = 12.51 μM. | 29635165 | ||
| A549 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human A549 cells after 72 hrs by MTT assay, IC50 = 13.18 μM. | 29635165 | ||
| TE1 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human TE1 cells after 72 hrs by MTT assay, IC50 = 16.53 μM. | 29635165 | ||
| HL60 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human HL60 cells after 72 hrs by MTT assay, IC50 = 3.46 μM. | 29635169 | ||
| Bel7402 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human Bel7402 cells after 72 hrs by MTT assay, IC50 = 18.97 μM. | 29635169 | ||
| SGC7901 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human SGC7901 cells after 72 hrs by MTT assay, IC50 = 19.84 μM. | 29635169 | ||
| MCF7 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay, IC50 = 26.91 μM. | 29635169 | ||
| Caco2 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human Caco2 cells after 72 hrs by MTT assay, IC50 = 38.77 μM. | 29635169 | ||
| MCF7 | Cytotoxicity assay | 48 hrs | Cytotoxicity in human MCF7 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay, IC50 = 16.7 μM. | 29657100 | ||
| MDA-MB-231 | Cytotoxicity assay | 48 hrs | Cytotoxicity in human MDA-MB-231 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay, IC50 = 35.91 μM. | 29657100 | ||
| DU145 | Cytotoxicity assay | 48 hrs | Cytotoxicity in human DU145 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay, IC50 = 39.17 μM. | 29657100 | ||
| A549 | Cytotoxicity assay | 48 hrs | Cytotoxicity in human A549 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay, IC50 = 39.86 μM. | 29657100 | ||
| HepG2 | Cytotoxicity assay | 6 days | Cytotoxicity against human HepG2 cells after 6 days by MTT assay, IC50 = 12 μM. | 29786436 | ||
| SGC7901 | Cytotoxicity assay | 6 days | Cytotoxicity against human SGC7901 cells after 6 days by MTT assay, IC50 = 12 μM. | 29786436 | ||
| HepG2 | Antiproliferative assay | Antiproliferative activity against human HepG2 cells by MTT assay, IC50 = 1.7 μM. | 29798826 | |||
| HeLa | Antiproliferative assay | Antiproliferative activity against human HeLa cells by MTT assay, IC50 = 1.8 μM. | 29798826 | |||
| MCF7 | Antiproliferative assay | Antiproliferative activity against human MCF7 cells by MTT assay, IC50 = 1.8 μM. | 29798826 | |||
| COLO205 | Antiproliferative assay | Antiproliferative activity against human COLO205 cells by MTT assay, IC50 = 1.9 μM. | 29798826 | |||
| HEK293 | Antiproliferative assay | Antiproliferative activity against human HEK293 cells by MTT assay, IC50 = 19.6 μM. | 29798826 | |||
| A549 | Cytotoxicity assay | Cytotoxicity against human A549 cells by MTS assay, IC50 = 3.52 μM. | 29843103 | |||
| HCT116 | Cytotoxicity assay | Cytotoxicity against human HCT116 cells by MTS assay, IC50 = 5.53 μM. | 29843103 | |||
| HeLa | Cytotoxicity assay | 72 hrs | Cytotoxicity against human HeLa cells assessed as decrease in cell viability after 72 hrs by MTT assay, IC50 = 7 μM. | 29908443 | ||
| McCoy | Cytotoxicity assay | 72 hrs | Cytotoxicity against mouse McCoy cells assessed as decrease in cell viability after 72 hrs by MTT assay, IC50 = 15.7 μM. | 29908443 | ||
| PC3 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay, IC50 = 8.45 μM. | 29958763 | ||
| HT-29 | Antiproliferative assay | 48 hrs | Antiproliferative activity against human HT-29 cells after 48 hrs by MTT assay, IC50 = 22.23 μM. | 29958763 | ||
| HeLa | Cytotoxicity assay | 48 hrs | Cytotoxicity against human HeLa cells after 48 hrs by MTT assay, IC50 = 30.21 μM. | 30007564 | ||
| HepG2 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay, IC50 = 36.62 μM. | 30007564 | ||
| 2008 | Cytotoxicity assay | Cytotoxicity against human 2008 cells, IC50 = 6 μM. | 30035541 | |||
| IGROV1 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human IGROV1 cells after 72 hrs, IC50 = 10.6 μM. | 30035541 | ||
| C13 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human C13 cells after 72 hrs, IC50 = 12.1 μM. | 30035541 | ||
| HCT8 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human HCT8 cells after 72 hrs by MTT assay, IC50 = 28.9 μM. | 30037494 | ||
| DLD1 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human DLD1 cells after 72 hrs by MTT assay, IC50 = 33 μM. | 30037494 | ||
| CCD-841-CoN | Antiproliferative assay | 72 hrs | Antiproliferative activity against human CCD-841-CoN cells after 72 hrs by MTT assay, IC50 = 35.7 μM. | 30037494 | ||
| SKOV3 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human SKOV3 cells after 48 hrs by MTT assay, IC50 = 26.34 μM. | 30092368 | ||
| HepG2 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay, IC50 = 31.98 μM. | 30092368 | ||
| Bel7404 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human Bel7404 cells after 48 hrs by MTT assay, IC50 = 40.21 μM. | 30092368 | ||
| NCI-H460 | Cytotoxicity assay | 48 hrs | Cytotoxicity against human NCI-H460 cells after 48 hrs by MTT assay, IC50 = 45.44 μM. | 30092368 | ||
| RKO | Growth inhibition assay | 48 hrs | Growth inhibition of human RKO cells after 48 hrs by CCK-8 assay, IC50 = 10.2 μM. | 30106289 | ||
| LoVo | Growth inhibition assay | 48 hrs | Growth inhibition of human LoVo cells after 48 hrs by CCK-8 assay, IC50 = 11.5 μM. | 30106289 | ||
| MCF7 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay, IC50 = 26.14 μM. | 30142612 | ||
| MGC803 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay, IC50 = 31.04 μM. | 30142612 | ||
| HCT116 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay, IC50 = 38.3 μM. | 30142612 | ||
| HepG2 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay, IC50 = 47.97 μM. | 30142612 | ||
| A549 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human A549 cells after 72 hrs by MTT assay, IC50 = 2.05 μM. | 30243153 | ||
| Bel7402 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human Bel7402 cells after 72 hrs by MTT assay, IC50 = 18.65 μM. | 30243153 | ||
| MCF7 | Antiproliferative assay | 72 hrs | Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay, IC50 = 27.89 μM. | 30243153 | ||
| T84 | Antiproliferative assay | 3 days | Antiproliferative activity against human T84 cells after 3 days by sulforhodamine B assay, IC50 = 3.4 μM. | 30248657 | ||
| A549 | Antiproliferative assay | 3 days | Antiproliferative activity against human A549 cells after 3 days by sulforhodamine B assay, IC50 = 7.1 μM. | 30248657 | ||
| MCF7 | Antiproliferative assay | 3 days | Antiproliferative activity against human MCF7 cells after 3 days by sulforhodamine B assay, IC50 = 7.8 μM. | 30248657 | ||
| A549 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human A549 cells after 72 hrs by MTT assay, IC50 = 4.3 μM. | 30318440 | ||
| HeLa | Cytotoxicity assay | 72 hrs | Cytotoxicity against human HeLa cells after 72 hrs by MTT assay, IC50 = 10.75 μM. | 30318440 | ||
| HCT116 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human HCT116 cells after 72 hrs by MTT assay, IC50 = 11.56 μM. | 30318440 | ||
| NCI-H460 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human NCI-H460 cells after 72 hrs by MTT assay, IC50 = 11.75 μM. | 30318440 | ||
| HCT15 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human HCT15 cells after 72 hrs by MTT assay, IC50 = 11.87 μM. | 30318440 | ||
| MDA-MB-231 | Cytotoxicity assay | 72 hrs | Cytotoxicity against human MDA-MB-231 cells after 72 hrs by MTT assay, IC50 = 21.05 μM. | 30318440 | ||
| Clicca per visualizzare più dati sperimentali sulle linee cellulari | ||||||
Informazioni chimiche, conservazione e stabilità
| Peso molecolare | 130.08 | Formula | C4H3FN2O2 |
Conservazione (Dalla data di ricezione) | |
|---|---|---|---|---|---|
| N. CAS | 51-21-8 | Scarica SDF | Conservazione delle soluzioni stock |
|
|
| Sinonimi | Fluorouracil, NSC 19893 | Smiles | C1=C(C(=O)NC(=O)N1)F | ||
Solubilità
|
In vitro |
DMSO
: 26 mg/mL
(199.87 mM)
Water : 10 mg/mL Ethanol : Insoluble |
Calcolatore di Molarità
Calcolatore di Diluizione
Calcolatore del Peso Molecolare
|
In vivo |
|||||
Calcolatore di formulazione in vivo (Soluzione chiara)
Passo 1: Inserire le informazioni di seguito (Consigliato: Un animale aggiuntivo per tenere conto della perdita durante lesperimento)
mg/kg
g
μL
Passo 2: Inserire la formulazione in vivo (Questo è solo il calcolatore, non la formulazione. Contattateci prima se non cè una formulazione in vivo nella sezione Solubilità.)
% DMSO
%
% Tween 80
% ddH2O
%DMSO
%
Risultati del calcolo:
Concentrazione di lavoro: mg/ml;
Metodo per preparare il liquido master di DMSO: mg farmaco predissolto in μL DMSO ( Concentrazione del liquido master mg/mL, Vi preghiamo di contattarci prima se la concentrazione supera la solubilità del DMSO del lotto del farmaco. )
Metodo per preparare la formulazione in vivo: Prendere μL DMSO liquido master, quindi aggiungereμL PEG300, mescolare e chiarire, quindi aggiungereμL Tween 80, mescolare e chiarire, quindi aggiungere μL ddH2O, mescolare e chiarire.
Metodo per preparare la formulazione in vivo: Prendere μL DMSO liquido master, quindi aggiungere μL Olio di mais, mescolare e chiarire.
Nota: 1. Si prega di assicurarsi che il liquido sia limpido prima di aggiungere il solvente successivo.
2. Assicurarsi di aggiungere il/i solvente/i in ordine. È necessario assicurarsi che la soluzione ottenuta, nellaggiunta precedente, sia una soluzione limpida prima di procedere allaggiunta del solvente successivo. Metodi fisici come il vortex, gli ultrasuoni o il bagno dacqua calda possono essere utilizzati per facilitare la dissoluzione.
Meccanismo dazione
| Targets/IC50/Ki |
Thymidylate synthase
(Tumor cells) |
|---|---|
| In vitro |
Adrucil
h
un analogo dell'uracile con un atomo di fluoro nella posizione C-5 al posto dell'idrogeno. Entra rapidamente nella cellula utilizzando lo stesso meccanismo di trasporto facilitato dell'uracile. Adrucil viene convertito intracellolarmente in diversi metaboliti attivi: fluorodeossiuridina monofosfato (FdUMP), fluorodeossiuridina trifosfato (FdUTP) e fluorouridina trifosfato (FUTP). Il metabolita di Adrucil, FdUMP, si lega al sito di legame nucleotidico della TS, formando un complesso ternario stabile con l'enzima e CH2THF, bloccando cos
h
il legame del substrato normale dUMP e inibendo la sintesi di dTMP. Il metabolita di Adrucil pu
h
anche essere incorporato in modo errato nel DNA, portando a rotture del filamento di DNA e alla morte cellulare. Gli effetti pro-apoptotici di Adrucil possono essere correlati alla sua attivazione del soppressore tumorale p53. La perdita di funzione di p53 riduce la sensibilit
h
cellulare ad Adrucil. Adrucil
h
in grado di inibire la sopravvivenza e indurre l'apoptosi in un'ampia gamma di cellule tumorali. Adrucil sopprime la vitalit
h
delle linee cellulari di carcinoma nasofaringeo CNE2 e HONE1 , delle linee cellulari di cancro al pancreas Capan-1 e della linea cellulare di carcinoma del colon umano HT-29 con IC50 di 9
h
g/mL, 3
h
g/mL, 0,22
h
M, 2,5
h
M, rispettivamente.
|
| In vivo |
Adrucil
h
ampiamente utilizzato nel trattamento di una vasta gamma di tumori, inclusi i tumori colorettali e al seno. 100mg/kg di Adrucil sopprime significativamente la crescita tumorale dei carcinomi del colon murini Colon 38 con un tempo di raddoppio tumorale (TD), un fattore di ritardo della crescita (GDF) e un T/C di 26,5 giorni, 4,4 e 14%.
|
Riferimenti |
|
Applicazioni
| Metodi | Biomarcatori | Immagini | PMID |
|---|---|---|---|
| Western blot | p53 / PUMA / c-PARP |
|
25965911 |
| Immunofluorescence | caveolin-3 phospho-histone H3 p65 / p-p65(Ser536) / p53 / p-p53(Ser15) Sox2 / Oct4 / Nanog / ABCG2 β-catenin non-phospho β-catenin |
|
23646193 |
| Growth inhibition assay | Cell viability Cell proliferation |
|
25965911 |
Informazioni sullo studio clinico
(dati da https://clinicaltrials.gov, aggiornato il 2024-05-22)
| Numero NCT | Reclutamento | Condizioni | Sponsor/Collaboratori | Data di inizio | Fasi |
|---|---|---|---|---|---|
| NCT06361316 | Recruiting | Pancreatic Cancer|Adjuvant Therapy |
Kuirong Jiang|CSPC Ouyi Pharmaceutical Co. Ltd.|The First Affiliated Hospital with Nanjing Medical University |
April 8 2024 | Not Applicable |
| NCT05780684 | Recruiting | Colorectal Cancer|Esophagus Cancer|Appendix Cancer|Small Bowel Cancer|Ampullary Cancer |
Dartmouth-Hitchcock Medical Center |
July 14 2023 | Not Applicable |
| NCT05362955 | Active not recruiting | CIN 2/3|HIV Infections |
UNC Lineberger Comprehensive Cancer Center |
April 26 2023 | Phase 1 |
| NCT05620524 | Recruiting | TDM of 5-FU|Pharmacokinetic Observational Study |
Catharina Ziekenhuis Eindhoven |
December 19 2022 | -- |
| NCT05505539 | Withdrawn | Oral Leukoplakia |
University of California San Francisco |
September 30 2022 | Phase 1 |
Supporto tecnico
Istruzioni per la manipolazione
Tel: +1-832-582-8158 Ext:3
Per qualsiasi altra domanda, si prega di lasciare un messaggio.
Domande Frequenti
Domanda 1:
I was wondering if it is suitable to inject this compound into mice ?
Risposta:
It is suitable to inject (I.P.) into mice as indicated in this paper: http://www.ncbi.nlm.nih.gov/pubmed/8995503.
I prodotti sono solo per uso di ricerca. Non per uso umano. Non vendiamo a pazienti.
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