Home Apoptosis Bcl-2 Bfl-1 Inhibitors

Bfl-1 Inhibitors

  • Bcl-2
  • Bcl-B
  • Bcl-w
  • Bcl-xL
  • Mcl-1
  • A1
  • Bax
  • Bfl-1
N. Cat. Nome del prodotto Informazioni Selettivo / Pan IC50 / Ki
S8061 Sabutoclax Sabutoclax(BI-97C1) is a pan-Bcl-2 inhibitor, including Bcl-xL, Bcl-2, Mcl-1 and Bfl-1 with IC50 of 0.31 μM, 0.32 μM, 0.20 μM and 0.62 μM, respectively. Pan Bfl-1, IC50: 0.62 μM
S2448 Gambogic Acid Gambogic Acid activates caspases with EC50 of 0.78-1.64 μM and competitively inhibits Bcl-XL, Bcl-2, Bcl-W, Bcl-B, Bfl-1 and Mcl-1 with IC50 of 1.47, 1.21, 2.02, 0.66, 1.06 and 0.79 μM, respectively. Pan Bfl-1, IC50: 1.06 μM