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PLK2 Inhibitors

  • PLK1
  • PLK2
  • PLK3
N. Cat. Nome del prodotto Informazioni Selettivo / Pan IC50 / Ki
S1109 BI 2536 BI2536 is a potent Plk1 inhibitor with IC50 of 0.83 nM. It shows 4- and 11-fold greater selectivity against Plk2 and Plk3. Phase 2. Pan PLK2, IC50: 3.5 nM
S7720 SBE 13 HCl SBE 13 HCl is a potent and selective PLK1 inhibitor with IC50 of 200 pM, >4000-fold selectivity over Aurora A kinase, Plk2 and Plk3. Pan PLK2, IC50: 66 μM