Home Metabolism Carbonic Anhydrase Carbonic Anhydrase II-Selettivo Inhibitors

Carbonic Anhydrase II-Selettivo Inhibitors

  • Carbonic Anhydrase I
  • Carbonic Anhydrase II
  • Carbonic Anhydrase IV
  • Carbonic Anhydrase IX
  • Carbonic Anhydrase XII
N. Cat. Nome del prodotto Informazioni Selettivo / Pan IC50 / Ki
S1375 Dorzolamide HCl Dorzolamide HCl is a water-soluble, potent inhibitor of human carbonic anhydrase II and IV with Ki of 1.9 nM and 31 nM, respectively, used as anti-glaucoma agent. Selective Carbonic anhydrase II, Ki: 1.9 nM
S3178 Brinzolamide Brinzolamide is a potent carbonic anhydrase II inhibitor with IC50 of 3.19 nM. Selective CAII, IC50: 3.19 nM
S4039 Methazolamide Methazolamide is a carbonic anhydrase inhibitor with Ki of 50 nM, 14 nM and 36 nM for hCA I, hCA II and bCA IV isoforms, respectively. Pan hCAII, Ki: 14 nM
S2866 U-104 U-104 is a potent carbonic anhydrase (CA) inhibitor for CA IX and CA XII with Ki of 45.1 nM and 4.5 nM, respectively, very low inhibition for CA I and CA II. Pan CAII, Ki: 9.64 μM