Home Neuronal Signaling -GPCR & G Protein -Transmembrane Transporters AChR mAChR-Selectief Inhibitors | Agonists | Antagonists

mAChR-Selectief Inhibitors | Agonists | Antagonists

  • mAChR
  • nAChR
  • AChE
Cat.nr. Productnaam Informatie Selectief / Pan IC50 / Ki
S4031 Aclidinium Bromide Aclidinium Bromide inhibits human muscarinic AChR M1, M2, M3, M4 and M5 with Ki of 0.1 nM, 0.14 nM, 0.14 nM, 0.21 nM and 0.16 nM, respectively. Selective M5 mAChR, Ki: 0.16 nM; M4 mAChR, Ki: 0.21 nM; M3 mAChR, Ki: 0.14 nM; M2 mAChR, Ki: 0.14 nM; M1 mAChR, Ki: 0.1 nM
S3144 Darifenacin HBr Darifenacin is a selective M3 muscarinic receptor antagonist with pKi of 8.9. Selective M3 mAChR, pKi: 8.9
S2130 Atropine Atropine is a competitive muscarinic acetylcholine receptor antagonist with an IC50 of 2.5 nM. Selective mAChR, IC50: 2.5 nM
S1913 Tropicamide Tropicamide is an anticholinergic and a muscarinic receptor subtype M4-preferring antagonist with IC50 of 8.0 nM. Selective M4 mAChR, IC50: 8 nM
S2508 Scopolamine HBr Scopolamine HBr is a competitive muscarinic acetylcholine receptor with an IC50 of 55.3 nM. Selective mAChR, IC50: 55.3 nM
S4024 Homatropine Methylbromide Homatropine Methylbromide is muscarinic AChR antagonist, inhibits endothelial and smooth muscle muscarinic receptors of WKY-E and SHR-E with IC50 of 162.5 nM and 170.3 nM, respectively. Selective mAChR (SHR-E), IC50: 170.3 nM; mAChR (WKY-E), IC50: 162.5 nM
S4025 Homatropine Bromide Homatropine Bromide is an muscarinic AChR antagonist, inhibits endothelial and smooth muscle muscarinic receptors of WKY-E and SHR-E with IC50 of 162.5 nM and 170.3 nM, respectively. Selective mAChR (SHR-E), IC50: 170.3 nM; mAChR (WKY-E), IC50: 162.5 nM
S4027 Flavoxate HCl Flavoxate is a muscarinic AChR antagonist with IC50 of 12.2 μM. Selective mAChR, IC50: 12.2 μM
S1683 Ipratropium Bromide Ipratropium Bromide is a muscarinic antagonist, bronchodilator, N-Isopropyl salt of atropine. Selective
S1978 Methscopolamine Methscopolamine is a muscarinic acetylcholine receptor blocker. Selective
S4143 Pentoxyverine Citrate Pentoxyverine Citrate is an antitussive (cough suppressant) commonly used for cough associated with illnesses like common cold. Selective
S4034 Diphemanil Methylsulfate Diphemanil Methylsulfate is a quaternary ammonium anticholinergic, it binds muscarinic acetycholine receptors (mAchR). Selective
S4292 Diphenidol HCl Diphenidol HCl is a potent antagonist of muscarinic M2 and M3 receptor with pKb of 6.72 and 7.02, respectively, used in the treatment of vomiting and vertigo. Selective
S3048 Solifenacin succinate Solifenacin succinate is a urinary antispasmodic of the antimuscarinic class. Selective
S2614 Arecoline Arecoline is a muscarinic acetylcholine receptor agonist. Selective
S2455 Bethanechol chloride Bethanechol chloride is a selective muscarinic receptor agonist without any effect on nicotinic receptors. Selective
S3047 Otilonium Bromide Otilonium bromide is an antimuscarinic. Selective
S4231 Pilocarpine HCl Pilocarpine HCl is a nonselective muscarinic acetylcholine receptor agonist used to produce an experimental model of epilepsy. Selective
S3117 Oxybutynin chloride Oxybutynin is an anticholinergic medication used to relieve urinary and bladder difficulties. Selective
S1929 Irsogladine Irsogladine is an anti-gastric ulcer agent that facilitates gap-junctional intercellular communication through M1 muscarininc acetylcholine receptor binding. Selective