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AChE-Selectief Inhibitors

  • mAChR
  • nAChR
  • AChE
Cat.nr. Productnaam Informatie Selectief / Pan IC50 / Ki
S2251 (-)-Huperzine A (HupA) (-)-Huperzine A is a potent, highly specific and reversible inhibitor of acetylcholinesterase (AChE) with Ki of 7 nM, exhibiting 200-fold more selectivity for G4 AChE over G1 AChE. Also acts as an NMDA receptor antagonist. Phase 4. Selective AChE (G4 form), Ki: 7 nM
S2462 Donepezil HCl Donepezil is a specific and potent AChE inhibitor for bAChE and hAChE with IC50 of 8.12 nM and 11.6 nM , respectively. Selective hAChE, IC50: 11.6 nM; bAChE, IC50: 8.12 nM
S1339 Galanthamine HBr Galanthamine is an AChE inhibitor with IC50 of 0.35 μM, exhibits 50-fold selectivity against butyryl-cholinesterase. Selective AChE, IC50: 0.35 μM